Chaperone gp96 mediates ER-α36 cell membrane expression

scientific article published on 10 September 2015

Chaperone gp96 mediates ER-α36 cell membrane expression is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.5273
P932PMC publication ID4741645
P698PubMed publication ID26396174

P2093author name stringFeng Chen
Jing Wang
Xin Li
Songdong Meng
Weiwei Liu
Xiaoyu Chu
Junwei Hou
Mengmeng Deng
P2860cites workA positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cellsQ24302285
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERADQ24312778
ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathwaysQ33528959
Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiolQ33564705
Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cellsQ33576337
Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signalingQ33780210
Synuclein gamma stimulates membrane-initiated estrogen signaling by chaperoning estrogen receptor (ER)-alpha36, a variant of ER-alpha.Q34033382
A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signalingQ34694795
Human estrogen receptor-alpha: regulation by synthesis, modification and degradation.Q34712217
Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cellsQ35239546
A positive cross-regulation of HER2 and ER-α36 controls ALDH1 positive breast cancer cellsQ35563328
Membrane estrogen signaling enhances tumorigenesis and metastatic potential of breast cancer cells via estrogen receptor-α36 (ERα36)Q35802058
ER-α36, a novel isoform of ER-α66, is commonly over-expressed in apocrine and adenoid cystic carcinomas of the breast.Q36048992
A variant of estrogen receptor-alpha, ER-alpha36 is expressed in human gastric cancer and is highly correlated with lymph node metastasisQ36049050
Hepatitis B virus mRNA-mediated miR-122 inhibition upregulates PTTG1-binding protein, which promotes hepatocellular carcinoma tumor growth and cell invasionQ36607449
Placenta-derived gp96 as a multivalent prophylactic cancer vaccineQ36907244
Proteasome-dependent degradation of the human estrogen receptorQ37160826
Tamoxifen resistance in breast cancerQ37224555
Identification of the cellular sentinels for native immunogenic heat shock proteins in vivo.Q37240798
Expression of ER-{alpha}36, a novel variant of estrogen receptor {alpha}, and resistance to tamoxifen treatment in breast cancerQ37280705
A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cellsQ37387466
Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPARQ38891038
Cell membrane gp96 facilitates HER2 dimerization and serves as a novel target in breast cancerQ38924681
Involvement of ER-α36 in the malignant growth of gastric carcinoma cells is associated with GRP94 overexpressionQ39129957
Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66.Q40373157
Estrogen receptor-α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cellsQ41134570
ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomasQ41889851
"Dwarf" estrogen receptor in breast cancer and resistance to tamoxifen.Q45987225
Cell surface expression of the endoplasmic reticular heat shock protein gp96 is phylogenetically conservedQ56902083
Tumor-specific cell surface expression of the -KDEL containing endoplasmic reticular heat shock protein gp96Q60021885
The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulatorsQ74265958
Transcriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched normal colorectal tissuesQ81783904
Evidence for U.S. Preventive Services Task Force (USPSTF) recommendations against routine mammography for females between 40-49 years of ageQ95545050
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectmolecular chaperonesQ422496
P304page(s)31857-31867
P577publication date2015-09-10
P1433published inOncotargetQ1573155
P1476titleChaperone gp96 mediates ER-α36 cell membrane expression
P478volume6

Reverse relations

cites work (P2860)
Q87611783Concomitant high expression of ERα36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior
Q55256765Estrogen receptor-α36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Q59797790Externalized Keratin 8: A Target at the Interface of Microenvironment and Intracellular Signaling in Colorectal Cancer Cells

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