Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma

scientific article published on 12 October 2015

Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.5556
P932PMC publication ID4741883
P698PubMed publication ID26473286
P5875ResearchGate publication ID282910406

P50authorHans Guenter DrexlerQ66431272
P2093author name stringCorinna Meyer
Maren Kaufmann
Stefan Nagel
Roderick A F MacLeod
P2860cites workTHE EVOLUTION OF ADAPTIVE IMMUNITYQ22255631
MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell linesQ24303516
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factorsQ24519076
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2CQ24532869
Identification of transcriptional regulators in the mouse immune systemQ24609000
Expression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomasQ24675877
A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In VivoQ27660498
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Transcriptional regulation of cranial sensory placode developmentQ28081644
Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulationQ28586846
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factorsQ28588872
An early haematopoietic defect in mice lacking the transcription factor GATA-2Q28593072
Evo-devo: variations on ancestral themesQ28755209
Classification and nomenclature of all human homeobox genes.Q30481102
NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cellsQ33511055
Molecular anatomy of placode development in Xenopus laevisQ47273875
Otx expression during lamprey embryogenesis provides insights into the evolution of the vertebrate head and jaw.Q48274586
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.Q51549649
Transcriptional deregulation of oncogenic myocyte enhancer factor 2C in T-cell acute lymphoblastic leukemia.Q51890625
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.Q52085890
Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor.Q52085976
Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma.Q53388471
Characterization of Early Stages of Human B Cell Development by Gene Expression ProfilingQ57599453
Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cellsQ73453075
β-Catenin signaling: no relevance in Hodgkin lymphoma?Q82173635
Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphomaQ33626623
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemiaQ33797115
Chordate evolution and the origin of craniates: an old brain in a new headQ33906919
Six family genes--structure and function as transcription factors and their roles in developmentQ33957333
Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.Q34112913
Gene expression profiling of microdissected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphomaQ34407534
Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes.Q34478174
Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.Q34520814
Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphomaQ34528341
Hox genes in hematopoiesis and leukemogenesis.Q34700749
Deregulated homeobox gene expression in cancer: cause or consequence?Q34932292
The sudden appearance of diverse animal body plansduring the Cambrian explosionQ34989235
Array-comparative genomic hybridization profiling of immunohistochemical subgroups of diffuse large B-cell lymphoma shows distinct genomic alterationsQ35051460
Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacityQ35078505
MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genomeQ35083272
The evolution of multicellularity and early animal genomesQ35592988
Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin LymphomaQ35788374
VLR-based adaptive immunityQ36478330
Bone marrow-induced Mef2c deficiency delays B-cell development and alters the expression of key B-cell regulatory proteins.Q36564419
Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determinationQ37259798
The six family of homeobox genes in development and cancerQ37341015
The biology of Hodgkin's lymphomaQ37349652
Pax5: a master regulator of B cell development and leukemogenesisQ37942333
Early embryonic specification of vertebrate cranial placodesQ38240042
Repressed BMP signaling reactivates NKL homeobox gene MSX1 in a T-ALL subsetQ38306982
Comparative expressed sequence hybridization studies of high-hyperdiploid childhood acute lymphoblastic leukemia.Q38521676
Deregulated FOX genes in Hodgkin lymphomaQ38973626
Oncogenic deregulation of NKL homeobox gene MSX1 in mantle cell lymphomaQ39062834
Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphomaQ39444125
Cytogenetic analysis of cancer cell linesQ39553835
Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcomeQ39722611
Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profilingQ39741184
Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.Q40200343
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphomaQ40337542
Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiationQ40435172
The early transcription factor GATA-2 is expressed in classical Hodgkin's lymphomaQ40493273
Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expressionQ42086899
Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysisQ42097322
P433issue37
P407language of work or nameEnglishQ1860
P304page(s)40112-40126
P577publication date2015-10-12
P1433published inOncotargetQ1573155
P1476titleAberrant expression of homeobox gene SIX1 in Hodgkin lymphoma
P478volume6

Reverse relations

cites work (P2860)
Q55281297Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset.
Q54987213Aberrant expression of NKL homeobox gene HLX in Hodgkin lymphoma.
Q64264591Deregulated expression of NKL homeobox genes in T-cell lymphomas
Q90352766Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9
Q61455094NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma
Q61807849Sine oculis homeobox 1 promotes proliferation and migration of human colorectal cancer cells through activation of Wnt/β-catenin signaling
Q57802286Use of flow cytometry in the phenotypic diagnosis of hodgkin's lymphoma

Search more.