The feline leukemia virus long terminal repeat contains a potent genetic determinant of T-cell lymphomagenicity

scientific article published on December 1997

The feline leukemia virus long terminal repeat contains a potent genetic determinant of T-cell lymphomagenicity is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID230290
P698PubMed publication ID9371646

P2093author name stringL S Levy
J Lenz
R M Beaty
J Pantginis
P2860cites workTissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequencesQ24645275
Virological events leading to spontaneous AKR thymomasQ28279811
Influence of enhancer sequences on thymotropism and leukemogenicity of mink cell focus-forming viruses.Q30452207
Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeatQ34255554
flvi-2, a target of retroviral insertional mutagenesis in feline thymic lymphosarcomas, encodes bmi-1.Q34356242
Feline leukemia virus: pathogenesis of neoplastic diseaseQ35233647
Feline leukemia virus infection and diseasesQ36465852
Virus-host interactions and the pathogenesis of murine and human oncogenic retrovirusesQ36468990
Oncogenicity of AKR endogenous leukemia virusesQ36521796
Escape from in vivo restriction of Moloney mink cell focus-inducing viruses driven by the Mo+PyF101 long terminal repeat (LTR) by LTR alterations.Q36655037
Two factors that bind to highly conserved sequences in mammalian type C retroviral enhancersQ36686005
Insertional mutagenesis of flvi-2 in tumors induced by infection with LC-FeLV, a myc-containing strain of feline leukemia virusQ36697386
Identification of the SL3-3 virus enhancer core as a T-lymphoma cell-specific elementQ36779962
Distinct segments within the enhancer region collaborate to specify the type of leukemia induced by nondefective Friend and Moloney virusesQ36780275
Differential protein binding in lymphocytes to a sequence in the enhancer of the mouse retrovirus SL3-3.Q36786744
Alignment of U3 region sequences of mammalian type C viruses: identification of highly conserved motifs and implications for enhancer designQ36800277
Relative importance of elements within the SL3-3 virus enhancer for T-cell specificityQ36804010
flvi-1, a common integration domain of feline leukemia virus in naturally occurring lymphomas of a particular typeQ36810891
Transcriptional initiation and postinitiation effects of murine leukemia virus long terminal repeat R-region sequencesQ36828988
Six distinct nuclear factors interact with the 75-base-pair repeat of the Moloney murine leukemia virus enhancerQ36836984
Disease specificity of nondefective Friend and Moloney murine leukemia viruses is controlled by a small number of nucleotidesQ36885330
Correlation of leukemogenic potential of murine retroviruses with transcriptional tissue preference of the viral long terminal repeats.Q36886343
Tissue-specific replication of Friend and Moloney murine leukemia viruses in infected miceQ36887187
A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virusQ36894915
Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific mannerQ36895296
The tandem direct repeats within the long terminal repeat of murine leukemia viruses are the primary determinant of their leukemogenic potentialQ36896896
Deregulation of the c-myc oncogene in virus-induced thymic lymphomas of AKR/J miceQ36900352
Nucleotide sequence of a transduced myc gene from a defective feline leukemia provirusQ36902841
Envelope gene and long terminal repeat determine the different biological properties of Rauscher, Friend, and Moloney mink cell focus-inducing virusesQ36902849
Early clonality and high-frequency proviral integration into the c-myc locus in AKR leukemiasQ36903499
Localization of the leukemogenic determinants of SL3-3, an ecotropic, XC-positive murine leukemia virus of AKR mouse originQ36907409
Thymotropism of murine leukemia virus is conferred by its long terminal repeatQ37341445
An enhancer variant of Moloney murine leukemia virus defective in leukemogenesis does not generate detectable mink cell focus-inducing virus in vivoQ37433347
Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomasQ37576088
A new class of murine leukemia virus associated with development of spontaneous lymphomasQ37582745
Tumorigenesis by slow-transforming retroviruses--an updateQ38012047
Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteinsQ38293060
Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer coresQ38296037
Detection of enhancer repeats in the long terminal repeats of feline leukemia viruses from cats with spontaneous neoplastic and nonneoplastic diseasesQ38327244
Long terminal repeat enhancer core sequences in proviruses adjacent to c-myc in T-cell lymphomas induced by a murine retrovirus.Q39868453
Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor: evidence for cooperativity with c-Myb.Q39875687
Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.Q39878116
Genetic determinants of feline leukemia virus-induced lymphoid tumors: patterns of proviral insertion and gene rearrangementQ40043158
SL3-3 enhancer factor 1 transcriptional activators are required for tumor formation by SL3-3 murine leukemia virusQ40106204
Structural diversity and nuclear protein binding sites in the long terminal repeats of feline leukemia virus.Q40108493
A DNA element responsible for the different tissue specificities of Friend and Moloney retroviral enhancersQ40114785
Sequences responsible for erythroid and lymphoid leukemia in the long terminal repeats of Friend-mink cell focus-forming and Moloney murine leukemia virusesQ40132598
Retroviral determinants of leukemogenesisQ40587932
Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activationQ41588412
Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificityQ43879286
Genetic determinants of feline leukemia virus-induced multicentric lymphomasQ45772215
Moloney virus induction of T-cell lymphomas in a plasmacytomagenic strain of E mu-v-abl transgenic mice.Q45774472
Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal regionQ45796591
Observations on lymphomagenesis and lymphoma in AKR mice. A description of prelymphoma changes in the thymus and phenotypic diversity of lymphomas induced by SL3-3 virusQ45872250
Conservation of the c-myc coding sequence in transduced feline v-myc genesQ48358178
Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertionQ48390929
A transgenic immunoglobulin mu gene prevents rearrangement of endogenous genes.Q53542857
Novel leukaemogenic retroviruses isolated from cell line derived from spontaneous AKR tumourQ57308162
Isolation of cDNA clones encoding T cell-specific membrane-associated proteinsQ59067678
Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcomaQ59098646
Spontaneous leukemia viruses: lymphomagenic ecotropic viruses of AKR miceQ72960590
Plaque assay techniques for murine leukemia virusesQ93694433
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
Feline leukemia virusQ769471
P304page(s)9786-9791
P577publication date1997-12-01
P1433published inJournal of VirologyQ1251128
P1476titleThe feline leukemia virus long terminal repeat contains a potent genetic determinant of T-cell lymphomagenicity
P478volume71

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cites work (P2860)
Q34328436Analysis of the disease potential of a recombinant retrovirus containing Friend murine leukemia virus sequences and a unique long terminal repeat from feline leukemia virus
Q39579211CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.
Q39551028Selection of reversions and suppressors of a mutation in the CBF binding site of a lymphomagenic retrovirus
Q33639086Sequence-specific and/or stereospecific constraints of the U3 enhancer elements of MCF 247-W are important for pathogenicity.
Q37747920Substitution of feline leukemia virus long terminal repeat sequences into murine leukemia virus alters the pattern of insertional activation and identifies new common insertion sites
Q39551832Suppressor mutations within the core binding factor (CBF/AML1) binding site of a T-cell lymphomagenic retrovirus.
Q39580918The secondary structure of the R region of a murine leukemia virus is important for stimulation of long terminal repeat-driven gene expression.
Q39642196Tumorigenic potential of a recombinant retrovirus containing sequences from Moloney murine leukemia virus and feline leukemia virus
Q35276737Viral determinants of FeLV infection and pathogenesis: lessons learned from analysis of a natural cohort

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