Gene disruption in mammals

scientific article published on August 1, 1991

Gene disruption in mammals is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0959-437X(05)80076-0
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0959437X05800760?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0959437X05800760?httpAccept=text/xml
P698PubMed publication ID1688005

P2093author name stringJ. Rossant
P2860cites workSubtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 HomeoboxQ24337933
Cloning of the T gene required in mesoderm formation in the mouseQ28236865
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1Q28508495
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locusQ28512134
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brainQ28586297
Novel myosin heavy chain encoded by murine dilute coat colour locusQ28590446
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar developmentQ28593581
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cellsQ29614545
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genesQ29618455
pp60c-src expression in the developing rat brainQ33573046
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombinationQ33825918
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptorQ34567286
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locusQ34776140
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cellsQ36958779
Using embryonic stem cells to introduce mutations into the mouse germ lineQ37679411
The new mouse genetics: altering the genome by gene targetingQ38646807
Towards a molecular-genetic analysis of mammalian developmentQ38727768
Homologous recombination in mammalian cellsQ38763375
Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesisQ39636157
Disruption of formin-encoding transcripts in two mutant limb deformity allelesQ41239288
Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cellsQ41710751
Murine developmental control genesQ43789032
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.Q46317908
Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel allelesQ48251836
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.Q52241373
Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination.Q52246995
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.Q52483113
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cellsQ57557434
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cellsQ59064557
Targetted correction of a mutant HPRT gene in mouse embryonic stem cellsQ59085795
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectgeneticsQ7162
mutagenesisQ149299
P304page(s)236-240
P577publication date1991-08-01
P1433published inCurrent Opinion in Genetics & DevelopmentQ13505684
P1476titleGene disruption in mammals
P478volume1

Reverse relations

cites work (P2860)
Q77327567Cytoarchitectural and metabolic adaptations in muscles with mitochondrial and cytosolic creatine kinase deficiencies
Q40861559Gene disruption in mice: models of development and disease
Q40382136Genetic knockouts in mice: an update
Q40901860Heat shock gene expression and development. II. An overview of mammalian and avian developmental systems
Q40585555More to learn from gene knockouts
Q36737130Of fin and fur: mutational analysis of vertebrate embryonic development
Q36333763Proto-oncogenes in mammalian development
Q73284728Use of gene targeting for compromising energy homeostasis in neuro-muscular tissues: the role of sarcomeric mitochondrial creatine kinase

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