Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments.

scientific article published on 21 December 2012

Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1202639
P932PMC publication ID3552136
P698PubMed publication ID23264658
P5875ResearchGate publication ID233977692

P50authorCésar Nombela-ArrietaQ57433322
P2093author name stringLeslie E Silberstein
Hilary E Beggs
Shin-Young Park
Gregory Pivarnik
John Manis
Brendan Harley
Kimberly Canty
Peter Wolfram
P2860cites workNuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradationQ24307387
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient miceQ24681021
Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cellsQ28264835
FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophiesQ28511784
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesisQ28591107
Focal adhesion kinase: the first ten yearsQ28609173
Focal adhesion kinase: in command and control of cell motilityQ29615192
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Q29616092
Focal adhesion kinase as a regulator of cell tension in the progression of cancerQ30440310
Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoidsQ30491268
Focal adhesion kinase regulates pathogen-killing capability and life span of neutrophils via mediating both adhesion-dependent and -independent cellular signals.Q30636627
Direct quantitation of T cell signaling by laser scanning cytometry.Q30786559
Dynamics and localization of early B-lymphocyte precursor cells (pro-B cells) in the bone marrow of scid miceQ31169665
The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironmentQ77402792
SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cellsQ81037245
Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cellsQ81232006
B cell receptor signaling involves physical and functional association of FAK with Lyn and IgM.Q33292164
Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockoutQ33376946
The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleenQ33859887
B cell development pathwaysQ34178187
Hematopoiesis is severely altered in mice with an induced osteoblast deficiencyQ34290169
Essential role for focal adhesion kinase in regulating stress hematopoiesisQ34360298
CXC chemokine ligand 12-induced focal adhesion kinase activation and segregation into membrane domains is modulated by regulator of G protein signaling 1 in pro-B cellsQ34397166
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonistQ34412254
Microenvironmental niches in the bone marrow required for B-cell developmentQ34496406
Early B-lymphocyte precursor cells in mouse bone marrow: subosteal localization of B220+ cells during postirradiation regenerationQ34509312
The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) miceQ34926717
Testing gene function early in the B cell lineage in mb1-cre miceQ35025083
Molecular cloning and structure of a pre-B-cell growth-stimulating factorQ35106000
Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expressionQ35834713
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilizationQ35888155
The role of focal-adhesion kinase in cancer - a new therapeutic opportunityQ36216076
Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesisQ36370653
Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrinQ36589367
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrowQ36735787
Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathwaysQ36964283
B lymphocyte-specific, Cre-mediated mutagenesis in miceQ39719513
FAK silencing inhibits leukemogenesis in BCR/ABL-transformed hematopoietic cellsQ39862369
Generation and characterization of stromal cell independent IL-7 dependent B cell linesQ40113979
Distinctive developmental origins and specificities of murine CD5+ B cellsQ40390845
Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosisQ40559142
The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flowQ40857641
p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines.Q41003800
Stimulation of tyrosine phosphorylation after ligation of beta7 and beta1 integrins on human B cells.Q41223742
Changes in frequencies of clonable pre B cells during life in different lymphoid organs of miceQ41558447
Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.Q46842240
Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biologyQ47234546
Cellular niches controlling B lymphocyte behavior within bone marrow during development.Q47365661
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cellsQ50912728
Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.Q51604860
SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis.Q51971637
Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells.Q53568387
Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.Q54728973
Generation of Ly-1 B cells from developmentally distinct precursors. Enrichment by stromal-cell culture or cell sortingQ67536955
The growth of mouse bone marrow cells in vitroQ70071283
Characterization of murine colony-forming B cells. II. Limits to in vitro maturation, Lyb-2 expression, resolution of IgD+ subsets, and further population analysisQ72072943
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1094-1102
P577publication date2012-12-21
P1433published inJournal of ImmunologyQ3521441
P1476titleFocal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments
P478volume190

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cites work (P2860)
Q39245050A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes
Q33708583A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing.
Q38614733Adhesion receptors involved in HSC and early-B cell interactions with bone marrow microenvironment
Q35507605Beta-Chemokine CCL15 Affects the Adhesion and Migration of Hematopoietic Progenitor Cells
Q93049082Cell circuits and niches controlling B cell development
Q61999522Cell circuits between B cell progenitors and IL-7 mesenchymal progenitor cells control B cell development
Q26781919Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science
Q47155047Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription.
Q41000106Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia
Q64251661Influenza Virus Infections and Cellular Kinases
Q35827910Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia
Q42814208Microfluidic generation of gradient hydrogels to modulate hematopoietic stem cell culture environment.
Q37188090Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks
Q58789359Murine Bone Marrow Niches from Hematopoietic Stem Cells to B Cells
Q26862927Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling
Q89777925Quantification and three-dimensional microanatomical organization of the bone marrow
Q90639050Regulation of Energy Metabolism during Early B Lymphocyte Development
Q36027764Regulation of leucocyte homeostasis in the circulation.
Q53605588SPARC deficiency affects bone marrow stromal function, resulting in impaired B lymphopoiesis.
Q92606063Targeting the proviral host kinase, FAK, limits influenza a virus pathogenesis and NFkB-regulated pro-inflammatory responses
Q35998365The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel
Q53032974VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions.

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