The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cells

scientific article published on October 1995

The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.15.10.5499
P932PMC publication ID230800
P698PubMed publication ID7565701

P2093author name stringB Hoffman
D A Liebermann
K Krishnaraju
H Q Nguyen
P2860cites workA novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogensQ70388052
Regulation and role of different macrophage-and granulocyte-inducing proteins in normal and leukemic myeloid cellsQ72103395
Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-AQ72191159
Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseasesQ24562724
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variantsQ33253667
Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cellsQ33584643
A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequencesQ33658729
Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the geneQ34378250
Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-mycQ34599313
In vivo and in vitro effects of TGF-beta 1 on normal and neoplastic haemopoiesisQ36401829
A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.Q36472744
The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cellsQ36649630
Induction of the granulocyte-macrophage colony-stimulating factor (CSF) receptor by granulocyte CSF increases the differentiative options of a murine hematopoietic progenitor cellQ36724862
Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both proliferating and terminally differentiated myeloid cellsQ36759593
Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complexQ37001430
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cellsQ38202008
The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineageQ38322297
The molecular control of blood cell developmentQ39682109
Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesisQ40654963
Posttranscriptional regulation of the zinc finger-encoding EGR-1 gene by granulocyte-macrophage colony-stimulating factor in human U-937 monocytic leukemia cells: involvement of a pertussis toxin-sensitive G proteinQ41680263
Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-mycQ41685649
Retinoic acid increases zif268 early gene expression in rat preosteoblastic cellsQ41686536
Methylation of an immediate-early inducible gene as a mechanism for B cell tolerance inductionQ41715009
Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiationQ42736547
Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibitionQ44684637
Proto-oncogene expression and dissection of the myeloid growth to differentiation developmental cascade.Q52246654
Control of normal differentiation of myeloid leukemic cells. XI. Induction of a specific requirement for cell viability and growth during the differentiation of myeloid leukemic cellsQ67826835
Dissection of the immediate early response of myeloid leukemia cells to terminal differentiation and growth inhibitory stimuliQ68377499
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)5499-5507
P577publication date1995-10-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cells
P478volume15

Reverse relations

cites work (P2860)
Q33775064CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors
Q28144569CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control
Q91474368Commensal microbiota drive the functional diversification of colon macrophages
Q28372880Copper-induced apoptosis and immediate early gene expression in macrophages
Q41646082Differentiation of myeloid cells and 1,25-dihydroxyvitamin D3.
Q41539807Early growth response 2 and Egr3 are unique regulators in immune system
Q36992618Early growth response genes regulate B cell development, proliferation, and immune response
Q40114099Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia
Q40433116Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation
Q39592066Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation.
Q41839426Expression of Egr-1 in late stage emphysema
Q41089601Expression of bcl-6 protein in normal skin and epidermal neoplasms
Q48479991Expression of the zinc finger Egr1 gene during zebrafish embryonic development
Q40671016Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors
Q45746783Haemopoietic progenitor cell lines generated by the myeloproliferative leukaemia virus: a model system to analyse murine and human lineage-affiliated genes
Q40352561High salt culture conditions suppress proliferation of rat C6 glioma cell by arresting cell-cycle progression at S-phase
Q40251961Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.
Q46051764Induction of early growth response-1 mediates microglia activation in vitro but is dispensable in vivo.
Q36376794Induction of the early growth response (Egr) family of transcription factors during thymic selection
Q89132869Inflammation-Induced Epithelial-to-Mesenchymal Transition and GM-CSF Treatment Stimulate Mesenteric Mesothelial Cells to Transdifferentiate into Macrophages
Q38318442Involvement of the NGFI-A gene in the differentiation of neuroblastoma cells
Q34310928Krox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone mass
Q39957933Leukemia suppressor function of Egr-1 is dependent on transforming oncogene
Q31011463Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing
Q42378332Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia
Q44485595Metallothioneins: Emerging Modulators in Immunity and Infection.
Q27011850Molecular control of monocyte development
Q36206254Molecular signatures of peripheral blood mononuclear cells during chronic interferon-α treatment: relationship with depression and fatigue
Q38836822Molecular targets of curcumin for cancer therapy: an updated review.
Q35143143Monocyte to macrophage differentiation goes along with modulation of the plasmalogen pattern through transcriptional regulation
Q34658552Myeloid differentiation (MyD) primary response genes in hematopoiesis
Q28215099Myeloid differentiation (MyD)/growth arrest DNA damage (GADD) genes in tumor suppression, immunity and inflammation
Q24323086NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli
Q35870331Proinflammatory role of leukocyte-derived Egr-1 in the development of murine postoperative ileus
Q36382766Recent insights into the signals that control alphabeta/gammadelta-lineage fate.
Q42466258Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation
Q33743319Regulation of lactoferrin gene expression by estrogen and epidermal growth factor: molecular mechanism
Q30637674SZF1: a novel KRAB-zinc finger gene expressed in CD34+ stem/progenitor cells
Q34139409Signal transduction and the Ets family of transcription factors
Q47828906The Molecular Mechanisms of Plant-Derived Compounds Targeting Brain Cancer.
Q46527502The early growth response factor-1 contributes to interleukin-13 production by mast cells in response to stem cell factor stimulation
Q37310026The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
Q40358798The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells
Q37695727The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes
Q50741658The molecular basis for the role of zinc in developmental biology.
Q28200929The proto-oncogene c-myc in hematopoietic development and leukemogenesis
Q36401394The transcription factor early growth response 1 (Egr-1) advances differentiation of pre-B and immature B cells
Q38354496The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells
Q36970209Transcriptional control of granulocyte and monocyte development
Q34658545Transcriptional regulation of granulocyte and monocyte development
Q34401921Transcriptional regulation of hemopoiesis
Q34719237Transcriptional regulation of myelopoiesis
Q36561742Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1).
Q73934753p53-independent apoptosis associated with c-Myc-mediated block in myeloid cell differentiation

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