Assessing the cost-benefit effect of a Plasmodium falciparum drug resistance mutation on parasite growth in vitro

scientific article published on 3 December 2012

Assessing the cost-benefit effect of a Plasmodium falciparum drug resistance mutation on parasite growth in vitro is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00950-12
P932PMC publication ID3553735
P698PubMed publication ID23208719

P50authorJosé Pedro GilQ50907208
Pedro E. FerreiraQ54802189
Anders BjörkmanQ80329586
Andreas MårtenssonQ91539704
Gabrielle FröbergQ91670807
P2093author name stringAbdullah Ali
P2860cites workEvidence of Artemisinin-Resistant Malaria in Western CambodiaQ22061854
Fitness and its role in evolutionary geneticsQ22122004
Amodiaquine for treating malariaQ24248644
Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquineQ24807027
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparumQ27861931
PfMDR1: mechanisms of transport modulation by functional polymorphismsQ28476753
Epidemiology of drug-resistant malariaQ30830669
A molecular marker for chloroquine-resistant falciparum malariaQ31921233
No seasonal accumulation of resistant P. falciparum when high-dose chloroquine is usedQ33498521
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in UgandaQ33676088
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutationsQ34198094
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparumQ34767732
The mechanisms of resistance to antimalarial drugs in Plasmodium falciparumQ35095240
Population pharmacokinetics of artesunate and amodiaquine in African childrenQ35575394
Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria.Q35647706
Contribution of the pfmdr1 gene to antimalarial drug-resistanceQ36117630
A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malariaQ37190605
Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysisQ37350167
Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).Q37422462
pfmdr1 mutations associated with chloroquine resistance incur a fitness cost in Plasmodium falciparumQ38331106
Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquineQ38980065
Simple histidine-rich protein 2 double-site sandwich enzyme-linked immunosorbent assay for use in malaria drug sensitivity testing.Q39307574
Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosisQ40572948
Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasitesQ40616078
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implicationsQ41292997
Decreased prevalence of Plasmodium falciparum resistance markers to amodiaquine despite its wide scale use as ACT partner drug in ZanzibarQ41827965
A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.Q41912137
Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in MalawiQ41915777
Assessment of the association between three pfmdr1 point mutations and chloroquine resistance in vitro of Malaysian Plasmodium falciparum isolates.Q41932849
A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum.Q41946696
Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East AfricaQ43945880
Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, TanzaniaQ43947607
Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y.Q46791619
The evolution of multiple drug resistance in malaria parasitesQ47837189
Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in ThailandQ47858805
Validation of Pyrosequencing for accurate and high throughput estimation of allele frequencies in malaria parasites.Q48037283
The cost of antibiotic resistance from a bacterial perspectiveQ64129151
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
parasite growthQ122674855
P304page(s)887-892
P577publication date2012-12-03
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleAssessing the cost-benefit effect of a Plasmodium falciparum drug resistance mutation on parasite growth in vitro
P478volume57

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cites work (P2860)
Q34597342Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response
Q40075854Differential gene expression in Anopheles stephensi following infection with drug-resistant Plasmodium yoelii
Q58586501Emerging implications of policies on malaria treatment: genetic changes in the gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa
Q35107675Fitness cost of resistance for lumefantrine and piperaquine-resistant Plasmodium berghei in a mouse model
Q36344786Fitness of artemisinin-resistant Plasmodium falciparum in vitro
Q35874266Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1
Q48024028Impact of treatment and re-treatment with artemether-lumefantrine and artesunate-amodiaquine on selection of Plasmodium falciparum multidrug resistance gene-1 polymorphisms in the Democratic Republic of Congo and Uganda
Q56440042Modelling the impact of antimalarial quality on the transmission of sulfadoxine-pyrimethamine resistance in
Q41547525Molecular characterization of the cytochrome b gene and in vitro atovaquone susceptibility of Plasmodium falciparum isolates from Kenya
Q37538729Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy
Q42246640Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy
Q22061938Pumped up: reflections on PfATP6 as the target for artemisinins
Q37425838Selection for chloroquine-sensitive Plasmodium falciparum by wild Anopheles arabiensis in Southern Zambia
Q39206934pfmdr1 (Plasmodium falciparum multidrug drug resistance gene 1): a pivotal factor in malaria resistance to artemisinin combination therapies

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