The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.

scientific article published on 31 October 2012

The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01158-12
P932PMC publication ID3554085
P698PubMed publication ID23115300

P50authorPatrice CodognoQ30111804
P2093author name stringIsabelle Beau
Jacqueline Cotte-Laffitte
Audrey Esclatine
Marion Lussignol
Christophe Queval
Marie-Françoise Bernet-Camard
P2860cites workGuidelines for the use and interpretation of assays for monitoring autophagyQ21996341
The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domainQ24292276
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Q24304261
Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 proteinQ24538727
Autophagy in immunity and inflammationQ24595707
Inhibition of Cellular 2'-5' Oligoadenylate Synthetase by the Herpes Simplex Virus Type 1 Us11 ProteinQ27478374
Autophagy, Immunity, and Microbial AdaptationsQ27489075
Viruses and autophagyQ27491341
Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11Q27652185
Autophagy fights disease through cellular self-digestionQ27860902
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagyQ28131727
The dsRNA protein kinase PKR: virus and cell controlQ28298945
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisQ28510028
Autophagy: renovation of cells and tissuesQ29547206
Methods in mammalian autophagy researchQ29547276
Regulation mechanisms and signaling pathways of autophagyQ29547416
The role of Atg proteins in autophagosome formationQ29547418
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3Q29614176
Eaten alive: a history of macroautophagyQ29617841
Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1Q33195896
A herpesvirus ribosome-associated, RNA-binding protein confers a growth advantage upon mutants deficient in a GADD34-related function.Q33645237
Translation initiation: adept at adaptingQ33740230
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cellsQ33775637
The second-site mutation in the herpes simplex virus recombinants lacking the gamma134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2alphaQ33783719
The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.Q33785225
Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 proteinQ33827148
A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animalsQ33851852
Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathwayQ33897064
Unique motif for nucleolar retention and nuclear export regulated by phosphorylationQ34300344
Signal integration via PKR.Q34467907
Herpesviruses and autophagy: catch me if you can!Q35260271
Nucleolin interacts with US11 protein of herpes simplex virus 1 and is involved in its traffickingQ35689672
Cellular autophagy: surrender, avoidance and subversion by microorganismsQ35697536
The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1Q35826084
Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitroQ35859934
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-Q35964369
Eating oneself and uninvited guests: autophagy-related pathways in cellular defenseQ36023948
Analysis of the role of autophagy in replication of herpes simplex virus in cell cultureQ36315492
The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunitsQ36698109
Viral stress-inducible genes.Q36926779
Control of TANK-binding kinase 1-mediated signaling by the gamma(1)34.5 protein of herpes simplex virus 1Q37036514
Binding and relocalization of protein kinase R by murine cytomegalovirusQ37099753
Varicella-zoster virus infection induces autophagy in both cultured cells and human skin vesiclesQ37191976
Autophagy genes in immunityQ37273997
Macroautophagy signaling and regulationQ37608022
Subversion of the cellular autophagy pathway by virusesQ37608053
Viral subversion of the host protein synthesis machineryQ37946208
Binding and nuclear relocalization of protein kinase R by human cytomegalovirus TRS1.Q39321563
Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycleQ39997686
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy proteinQ40051258
The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomesQ40250494
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in cultureQ44460699
PKR-dependent autophagic degradation of herpes simplex virus type 1.Q45413954
Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.Q50603646
Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controlsQ57662953
Protection against heat and staurosporine mediated apoptosis by the HSV-1 US11 proteinQ81037405
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)859-871
P577publication date2012-10-31
P1433published inJournal of VirologyQ1251128
P1476titleThe herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
P478volume87

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