Epigenetics of early-life lead exposure and effects on brain development

scientific article published on December 2012

Epigenetics of early-life lead exposure and effects on brain development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.2217/EPI.12.58
P932PMC publication ID3555228
P698PubMed publication ID23244311
P5875ResearchGate publication ID233938089

P2093author name stringHelmut Hirsch
Adele Kruger
Steven T Suhr
Pablo Cingolani
Douglas Ruden
Arko Sen
Asra Shaik
Marie-Claude Senut
P2860cites workDecreased brain volume in adults with childhood lead exposureQ21144652
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Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult ratsQ35843110
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Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to agingQ36074468
Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure levelQ36402061
Low-level human equivalent gestational lead exposure produces sex-specific motor and coordination abnormalities and late-onset obesity in year-old miceQ36490893
MicroRNAs in neuronal function and dysfunctionQ36589809
Gender differences in the disposition and toxicity of metalsQ36601386
Epigenetic regulation of neural gene expression and neuronal functionQ36783152
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.Q36793926
Gender specific differences in neurodevelopmental effects of prenatal exposure to very low-lead levels: the prospective cohort study in three-year oldsQ37050721
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Chronic lead exposure alters presynaptic calcium regulation and synaptic facilitation in Drosophila larvaeQ37486027
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Epigenetic targets of some toxicologically relevant metals: a review of the literatureQ37984019
Crosstalk among Epigenetic Pathways Regulates NeurogenesisQ38010167
DNA methylation and its basic functionQ38025275
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testingQ38504903
Protective effect of 17-beta-estradiol in human neurocellular models of lead exposureQ40283077
Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memoryQ40888422
Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's diseaseQ42727070
Epigenetic assessment of environmental chemicals detected in maternal peripheral and cord blood samplesQ42733648
p16 promoter methylation in Pb2+ -exposed individualsQ43144175
The fetal and infant origins of adult diseaseQ43172631
In vitro differentiation of transplantable neural precursors from human embryonic stem cellsQ43814659
Histone deacetylase activity is necessary for oligodendrocyte lineage progression.Q44228541
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal.Q44743806
The impact of early childhood lead exposure on brain organization: a functional magnetic resonance imaging study of language functionQ48429930
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Co-exposure to environmental lead and manganese affects the intelligence of school-aged children.Q51818036
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P433issue6
P407language of work or nameEnglishQ1860
P921main subjectleadQ708
P304page(s)665-674
P577publication date2012-12-01
P1433published inEpigenomicsQ20737165
P1476titleEpigenetics of early-life lead exposure and effects on brain development
P478volume4

Reverse relations

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Q28392345Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood
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Q37265405Original Research: The expression of MMP2 and MMP9 in the hippocampus and cerebral cortex of newborn mice under maternal lead exposure
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