Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae

scientific article published on May 1997

Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.17.5.2723
P932PMC publication ID232123
P698PubMed publication ID9111343

P2093author name stringX Li
M Cai
P2860cites workThe p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear divisionQ24555684
Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeastQ24564643
Transformation of intact yeast cells treated with alkali cationsQ24672708
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
WAF1, a potential mediator of p53 tumor suppressionQ27861121
The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiaeQ27931492
Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiaeQ27932554
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule functionQ27934127
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repairQ27935229
Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiaeQ27936499
Full activation of p34CDC28 histone H1 kinase activity is unable to promote entry into mitosis in checkpoint-arrested cells of the yeast Saccharomyces cerevisiaeQ27937833
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiaeQ27939221
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiaeQ27939590
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpointQ27939822
Multifunctional yeast high-copy-number shuttle vectorsQ28131605
Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeastQ28131609
Checkpoints: controls that ensure the order of cell cycle eventsQ28131705
p21 is a universal inhibitor of cyclin kinasesQ28257305
Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeastQ28300714
p53 mutations in human cancersQ28302973
Cell cycle control and cancerQ29617536
The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiaeQ29618309
Participation of p53 protein in the cellular response to DNA damageQ29618319
Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae.Q33951030
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.Q33960935
Control of the yeast cell cycle by the Cdc28 protein kinaseQ34366247
Creative blocks: cell-cycle checkpoints and feedback controlsQ35405693
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cellsQ35476763
Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damageQ36774976
Wild-type p53 is a cell cycle checkpoint determinant following irradiationQ37152060
The p53 tumour suppressor geneQ37751892
Checkpoints in the cell cycle of fission yeastQ40525065
The genetics of cell cycle checkpointsQ40525099
Exercising self-restraint: discouraging illicit acts of S and M in eukaryotesQ40831219
From DNA damage to cell cycle arrest and suicide: a budding yeast perspectiveQ41099898
Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiationQ41323588
S-phase feedback control in budding yeast independent of tyrosine phosphorylation of P34cdc28Q46009345
Analysis and manipulation of yeast mitochondrial genesQ67684858
Mitotic checkpoint control in fission yeastQ67893125
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replicationQ68929092
Ordering S phase and M phase in the cell cycleQ72790820
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
DNA damageQ5205747
P304page(s)2723-2734
P577publication date1997-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae
P478volume17

Reverse relations

cites work (P2860)
Q28144150A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2
Q42246352Adaptation to the spindle checkpoint is regulated by the interplay between Cdc28/Clbs and PP2ACdc55
Q52547709An essential function of yeast cyclin-dependent kinase Cdc28 maintains chromosome stability.
Q21203553An overview of Cdk1-controlled targets and processes
Q35022527BCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability
Q27930799CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint
Q36328318Cdc28 activates exit from mitosis in budding yeast.
Q37237633Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae.
Q64884281Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity.
Q27933316Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest
Q34282259Checking out the G(2)/M transition.
Q33824746Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.
Q27937263DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.
Q62657002DNA damage checkpoints update: getting molecular
Q33947036DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts
Q90350226Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing
Q34281241Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis
Q27934574Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80.
Q24336250Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
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Q55239937Mutation analysis of mitotic checkpoint genes (hBUB1 and hBUBR1) and microsatellite instability in adult T-cell leukemia/lymphoma.
Q44492139Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint
Q47715063NET1 and HFI1 genes of yeast mediate both chromosome maintenance and mitochondrial rho(-) mutagenesis
Q37653615Overcoming inhibition in the spindle checkpoint
Q36328322Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex
Q30448350RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast
Q78122354Recovery of the yeast cell cycle from heat shock-induced G(1) arrest involves a positive regulation of G(1) cyclin expression by the S phase cyclin Clb5
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Q27934148Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p
Q41348459The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase.
Q41678505The metaphase-to-anaphase transition: avoiding a mid-life crisis

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