Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations

scientific article published on 10 October 2015

Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1068965806
P356DOI10.2119/MOLMED.2015.00232
P932PMC publication ID4749491
P698PubMed publication ID26562150

P50authorLennart HammarströmQ5786999
Peter K. GregersenQ7175067
Piotr SzczudlikQ56506957
Janine A LambQ57008662
Anna Kostera-PruszczykQ61638820
Hanne F HarboQ90089338
Benedicte A LieQ90324535
Michael F SeldinQ107119154
Omar K AlkhairyQ125218742
Ritva Pirskanen-MatellQ125219775
P2093author name stringAnnette T Lee
Fredrik Piehl
Arthur Melms
Angelina H Maniaol
Nicholas Willcox
Henri-Jean Garchon
Jon Sussman
J J G M Verschuuren
David Mckee
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Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysisQ28141482
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetesQ28248848
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritisQ28267921
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.Q28273794
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Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotypeQ28305142
RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoterQ28567333
Novel associations for hypothyroidism include known autoimmune risk lociQ28730714
Late-onset myasthenia gravis - CTLA4(low) genotype association and low-for-age thymic output of naïve T cells.Q50800911
Estrogen receptor-alpha deficiency attenuates autoimmune disease in (NZB x NZW)F1 mice.Q52584591
A susceptibility region for myasthenia gravis extending into the HLA-class I sector telomeric to HLA-C.Q52916174
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Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravisQ72079873
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Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodiesQ77162347
Clonal expansions of CD4+ B helper T cells in autoimmune myasthenia gravisQ79833067
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Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08Q28943379
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Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.Q34039427
The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.Q34042062
Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic valueQ34068275
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritisQ34250412
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureQ34268288
Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian populationQ34270872
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulationQ34350941
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minimac2: faster genotype imputationQ34444539
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Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of boneQ35552797
Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritisQ35834701
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epitheliumQ36011240
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in EuropeansQ36365695
DNase I sensitivity QTLs are a major determinant of human expression variationQ36408973
A genome-wide association study of myasthenia gravisQ36869250
Lifetime course of myasthenia gravisQ37024294
Autoimmune myasthenia gravis: emerging clinical and biological heterogeneityQ37315963
The X chromosome and the sex ratio of autoimmunity.Q37966537
Genetic basis of myasthenia gravis - a comprehensive reviewQ38173147
IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3.Q40872798
The role of Sp1 and NF-kappa B in regulating CD40 gene expressionQ42514630
Correlating extent of neuromuscular instability with acetylcholine receptor antibodiesQ46101147
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis.Q46912103
Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.Q48292937
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesgenome-wide association studyQ1098876
P407language of work or nameEnglishQ1860
P921main subjectmyasthenia gravisQ8285
genome-wide association studyQ1098876
P577publication date2015-10-10
P1433published inMolecular MedicineQ6895961
P1476titleGenome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations

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cites work (P2860)
Q26765172Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society
Q37191879Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma
Q47192132Immunopathogenesis in Myasthenia Gravis and Neuromyelitis Optica
Q42696048Juvenile myasthenia gravis in Norway: HLA-DRB1*04:04 is positively associated with prepubertal onset.
Q36715524Sonic Hedgehog regulates thymic epithelial cell differentiation
Q33714351TNFAIP3 gene rs7749323 polymorphism is associated with late onset myasthenia gravis.
Q46094020The immunogenetics of neurological disease.

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