A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis

scientific article published on June 1997

A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.17.6.3388
P932PMC publication ID232192
P698PubMed publication ID9154838

P2093author name stringF Osaka
T Seno
H Seino
F Yamao
P2860cites workA family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligaseQ24313174
CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transitionQ24316218
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53Q24317677
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosisQ24656114
A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosisQ27932478
The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzymeQ27933363
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzymeQ27933609
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclinsQ27937265
The recognition component of the N-end rule pathwayQ27937878
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiaeQ27939221
Cyclin is degraded by the ubiquitin pathwayQ28131704
Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeastQ28300714
The ubiquitin-proteasome proteolytic pathwayQ29618638
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like propertiesQ29620009
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin BQ29620071
Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.Q34365395
The role of cyclin synthesis and degradation in the control of maturation promoting factor activityQ34667889
Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor.Q34729839
Cut2 proteolysis required for sister-chromatid seperation in fission yeastQ34733084
The ubiquitin-conjugation systemQ35237882
Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies.Q35662119
A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transitionQ36797998
E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclinsQ37635419
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdownQ38583853
Ubiquitin, proteasomes, and the regulation of intracellular protein degradationQ40445002
Dominant mutants identify new roles for p34cdc2 in mitosis.Q40806692
Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25.Q41064205
Both cyclin A delta 60 and B delta 97 are stable and arrest cells in M-phase, but only cyclin B delta 97 turns on cyclin destructionQ41083910
Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organizationQ41577155
Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphaseQ41764313
Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesisQ42155564
nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamineQ42636951
Expression of a dominant negative allele of cdc2 prevents activation of the endogenous p34cdc2 kinaseQ44502430
The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.Q48075170
Methylated ubiquitin inhibits cyclin degradation in clam embryo extractsQ50797700
"Covalent affinity" purification of ubiquitin-activating enzymeQ55062459
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinaseQ56490708
Defective mitosis due to a mutation in the gene for a fission yeast 26S proteasesubunitQ59091728
The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombeQ67980916
Regulation of p34cdc2 protein kinase during mitosisQ69520047
TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibilityQ70536012
The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycleQ71056381
Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradationQ71301624
Schizosaccharomyces pombe and candida albicans cDNA homologues of the saccharomyces cerevisiae UBC4 geneQ72114922
Two new multi-purpose multicopy Schizosaccharomyces pombe shuttle vectors, pSP1 and pSP2Q72800804
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)3388-3397
P577publication date1997-06-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleA ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis
P478volume17

Reverse relations

cites work (P2860)
Q29547805A genome-wide transcriptional analysis of the mitotic cell cycle
Q40370214APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome
Q24291991APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex
Q36798089An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast
Q38486141Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome
Q30454298Cell cycle-regulated proteolysis of mitotic target proteins
Q27932131Functional analysis of the Saccharomyces cerevisiae UBC11 gene
Q59407339Molecular characterization of plant ubiquitin-conjugating enzymes belonging to the UbcP4/E2-C/UBCx/UbcH10 gene family
Q34787497Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast
Q43795334Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast
Q37863285Processive ubiquitin chain formation by the anaphase-promoting complex.
Q33331784Rapid regulation of protein activity in fission yeast
Q37015055Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1).
Q41678499Roles of ubiquitin-mediated proteolysis in cell cycle control
Q36867692State of the APC/C: organization, function, and structure
Q27638680Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10
Q37811107Structure, function and mechanism of the anaphase promoting complex (APC/C)
Q27934826The APC11 RING-H2 finger mediates E2-dependent ubiquitination
Q39618536The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region.
Q27860803The ubiquitin system
Q42928048The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.
Q27640544The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
Q35148624Two Ubiquitin-Conjugating Enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, Have Distinct Functions for Ubiquitination of Mitotic Cyclin
Q48372990Two WD repeat-containing TATA-binding protein-associated factors in fission yeast that suppress defects in the anaphase-promoting complex
Q64935679UBE2C overexpression in melanoma and its essential role in G2/M transition.
Q24324253UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit
Q36023888lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2.

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