Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo

scientific article published on 30 January 2013

Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1044379747
P356DOI10.1038/SREP01165
P932PMC publication ID3558697
P698PubMed publication ID23372922
P5875ResearchGate publication ID235393596

P50authorChristian M ParobekQ55174923
Venkatachalam UdhayakumarQ60032286
Steven R. MeshnickQ62070963
P2093author name stringAntoinette K Tshefu
Michael Emch
Jonathan J Juliano
Steve M Taylor
Md Tauqeer Alam
Mark Janko
Alejandro L Antonia
P2860cites workMolecular malaria epidemiology: mapping and burden estimates for the Democratic Republic of the Congo, 2007Q21562114
Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction dataQ24532809
The neighbor-joining method: a new method for reconstructing phylogenetic treesQ25939010
Median-joining networks for inferring intraspecific phylogeniesQ27860619
Origin and evolution of sulfadoxine resistant Plasmodium falciparumQ28473479
High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581Q28474860
Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malariaQ28475195
Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Mali: a randomised, double-blind, placebo-controlled trialQ28477050
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Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic reviewQ33288230
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Molecular correlates of high-level antifolate resistance in Rwandan children with Plasmodium falciparum malariaQ33559071
Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey dataQ33805770
Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malariaQ33889085
Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populationsQ34134036
Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?Q34470236
Tracking Origins and Spread of Sulfadoxine-Resistant Plasmodium falciparum dhps Alleles in ThailandQ34483523
Selective sweeps and genetic lineages of plasmodium falciparum drug -resistant alleles in GhanaQ34763548
Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populationsQ35532863
Quantification of the burden and consequences of pregnancy-associated malaria in the Democratic Republic of the CongoQ36792779
Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central AfricaQ36949559
dhfr and dhps genotype and sulfadoxine-pyrimethamine treatment failure in children with falciparum malaria in the Democratic Republic of CongoQ37396146
Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trialsQ37600130
Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistanceQ38879770
Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda.Q38881371
Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo.Q38950001
Intercontinental spread of pyrimethamine-resistant malariaQ39408056
Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.Q40469006
Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso.Q41944962
Frequency distribution of antimalarial drug-resistant alleles among isolates of Plasmodium falciparum in Bangui, Central African Republic.Q41945894
A new statistic for detecting genetic differentiation.Q42552289
Sampling variances of heterozygosity and genetic distanceQ42973470
Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparumQ46282106
Therapeutic efficacy of sulfadoxine-pyrimethamine and the prevalence of molecular markers of resistance in under 5-year olds in Brazzaville, CongoQ46935373
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesArcGISQ513297
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
P304page(s)1165
P577publication date2013-01-30
P1433published inScientific ReportsQ2261792
P1476titlePlasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo
P478volume3

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cites work (P2860)
Q46688458A deep sequencing approach to estimate Plasmodium falciparum complexity of infection (COI) and explore apical membrane antigen 1 diversity
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Q35471937The geography of malaria genetics in the Democratic Republic of Congo: A complex and fragmented landscape
Q94474134The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC

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