Transdermal Delivery of siRNA through Microneedle Array

scientific article published on 18 February 2016

Transdermal Delivery of siRNA through Microneedle Array is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1031746570
P356DOI10.1038/SREP21422
P8608Fatcat IDrelease_g4chqk4qaveythw63tislvvxye
P932PMC publication ID4757825
P698PubMed publication ID26888011
P5875ResearchGate publication ID295089034

P50authorBruce K. GaleQ39476061
Li ZhangQ43714779
P2093author name stringYi Zhao
Jiao Chen
Yan Deng
Tao Tang
Jun Hu
Xiaohui Yan
Himanshu J Sant
Kwongwai Choy
P2860cites workInhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arraysQ30524055
Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array DeviceQ30578477
Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promotersQ33576601
Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studiesQ33712814
First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.Q33730680
Effect of microneedle design on pain in human volunteersQ34048990
Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD)Q34209790
Elimination pathways of systemically delivered siRNA.Q34556940
RNAi therapeutics: principles, prospects and challengesQ34621268
Permeation of antigen protein-conjugated nanoparticles and live bacteria through microneedle-treated mouse skinQ35090493
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Microneedles for drug and vaccine deliveryQ36164749
Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model.Q36482238
Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-conceptQ36674114
Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies.Q38177110
A survey on "Trojan Horse" peptides: opportunities, issues and controlled entry to "Troy".Q38242733
Therapeutic face of RNAi: in vivo challengesQ38268541
siRNA-mediated knock-down of COX-2 in melanocytes suppresses melanogenesisQ39364122
Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita modelQ39605490
Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivityQ40039657
Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting MitfQ40223081
A Wafer-Scale Etching Technique for High Aspect Ratio Implantable MEMS StructuresQ42016610
A microneedle roller for transdermal drug deliveryQ42972564
Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cellsQ45040403
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAsQ45147309
Therapeutic RNA interference targeting CKIP-1 with a cross-species sequence to stimulate bone formation.Q45242278
Development of quantitative molecular clinical end points for siRNA clinical trialsQ46205464
Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug deliveryQ46468179
Microneedle mediated delivery of nanoparticles into human skin.Q47331967
Clinical administration of microneedles: skin puncture, pain and sensation.Q47426250
A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy.Q54326868
Nanocomposite-Strengthened Dissolving Microneedles for Improved Transdermal Delivery to Human SkinQ61609395
Microfabricated microneedles: A novel approach to transdermal drug deliveryQ78232748
Modulation of scratching behavior by silencing an endogenous cyclooxygenase-1 gene in the skin through the administration of siRNAQ80805732
Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cellsQ81227736
Oncogenic BRAF is required for tumor growth and maintenance in melanoma modelsQ82310241
CXCL1 gene silencing in skin using liposome-encapsulated siRNA delivered by microprojection arrayQ85258344
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)21422
P577publication date2016-02-18
P1433published inScientific ReportsQ2261792
P1476titleTransdermal Delivery of siRNA through Microneedle Array
P478volume6

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cites work (P2860)
Q37380657An Improved Manufacturing Approach for Discrete Silicon Microneedle Arrays with Tunable Height-Pitch Ratio
Q55280847Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs.
Q90452289Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo
Q48331228Getting Drugs Across Biological Barriers.
Q88626468Improving siRNA Delivery In Vivo Through Lipid Conjugation
Q48531728Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles
Q37125566Local administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity.
Q51737325Oligonucleotide therapeutics in neurodegenerative diseases.
Q47189515Recent Advances in Wearable Transdermal Delivery Systems
Q47666014Recent advances of controlled drug delivery using microfluidic platforms.
Q47990517The self-recovery of facial skin barrier and erythema after nanochip treatment
Q64982493Tissue Interlocking Dissolving Microneedles for Accurate and Efficient Transdermal Delivery of Biomolecules.
Q45325246siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

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