Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

scientific article published on 6 January 2013

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM.3056
P8608Fatcat IDrelease_bhp2k2vjevexjgwt5oeivavwu4
P932PMC publication ID3567215
P698PubMed publication ID23291629
P5875ResearchGate publication ID234067610

P50authorMatthias BlüherQ15431947
Stephen R FarmerQ37381270
Dominique LanginQ41580270
Cristina MallolQ42409757
Alessandro DoriaQ54241891
P2093author name stringChong Wee Liew
Jeremie Boucher
Rohit N Kulkarni
Jiang Hu
Ho-Jin Koh
Cecile Vernochet
Marc K Hellerstein
Dan Kawamori
Yu-Hua Tseng
Jit Kong Cheong
Stephen I-Hong Hsu
Kristy Townsend
Laurie Goodyear
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TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumorsQ37164834
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The PHD type zinc finger is an integral part of the CBP acetyltransferase domainQ39674188
Overexpression of SERTAD3, a putative oncogene located within the 19q13 amplicon, induces E2F activity and promotes tumor growthQ40177755
Transcriptional and subcellular regulation of the TRIP-Br familyQ40201734
CDCA4 is an E2F transcription factor family-induced nuclear factor that regulates E2F-dependent transcriptional activation and cell proliferationQ40229927
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cellsQ40232298
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Adipocyte lipases and defect of lipolysis in human obesityQ42485763
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Relation between glycaemic control, hyperinsulinaemia and plasma concentrations of soluble adhesion molecules in patients with impaired glucose tolerance or Type II diabetesQ43949023
Human alpha 2A-adrenergic receptor gene expressed in transgenic mouse adipose tissue under the control of its regulatory elements.Q44172038
Measurement of TG synthesis and turnover in vivo by 2H2O incorporation into the glycerol moiety and application of MIDA.Q44489677
A novel, noninvasive method for the measurement of intestinal fat absorptionQ44965228
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in miceQ45161342
Cyclophilin a protects Peg3 from hypermethylation and inactive histone modification.Q46036705
Understanding adipocyte differentiationQ46119331
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A war on obesity, not the obeseQ48606186
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.Q51555890
The TRIP-Br family of transcriptional regulators is essential for the execution of cyclin E-mediated cell cycle progression.Q53621334
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.Q54104864
Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia.Q54154717
Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysisQ57420163
Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2Q60192390
Reduction of dietary obesity in aP2-Ucp transgenic mice: mechanism and adipose tissue morphologyQ71897706
The role of leptin in human physiologyQ72989659
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
thermogenesisQ965695
insulin resistanceQ1053470
P304page(s)217-226
P577publication date2013-01-06
P1433published inNature MedicineQ1633234
P1476titleAblation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance
P478volume19

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