review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Adriano Aguzzi | Q375410 |
Mathias Heikenwalder | Q43369827 | ||
P2860 | cites work | A Toll-like receptor recognizes bacterial DNA | Q24290668 |
The prion protein gene in humans revisited: lessons from a worldwide resequencing study | Q24537613 | ||
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal | Q24541459 | ||
Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanism | Q24679391 | ||
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles | Q25257725 | ||
Agent replication dynamics in a long incubation period model of mouse scrapie | Q48431705 | ||
Presymptomatic detection of prions in blood. | Q48477099 | ||
Selective expression of prion protein in peripheral tissues of the adult mouse | Q48544898 | ||
A crucial role for B cells in neuroinvasive scrapie. | Q48574532 | ||
Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep | Q48598161 | ||
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain | Q48630602 | ||
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease | Q48691137 | ||
Coincident scrapie infection and nephritis lead to urinary prion excretion | Q48730761 | ||
Competition between Different Scrapie Agents in Mice | Q48752287 | ||
Very Early Replication of Scrapie in Lymphocytic Tissue | Q48882800 | ||
The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies | Q48913771 | ||
Complement facilitates early prion pathogenesis | Q48930440 | ||
Pre-symptomatic detection of prions by cyclic amplification of protein misfolding. | Q49113318 | ||
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. | Q51027456 | ||
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. | Q51037857 | ||
vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true? | Q51037865 | ||
Developmental expression of the prion protein gene in glial cells | Q52209886 | ||
Binding of disease-associated prion protein to plasminogen. | Q52541671 | ||
Migrating intestinal dendritic cells transport PrP(Sc) from the gut. | Q53676141 | ||
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. | Q54014234 | ||
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. | Q54037114 | ||
NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231). | Q54559823 | ||
Prion Diseases and a Penchant for Brains | Q57039333 | ||
PrPSc in mammary glands of sheep affected by scrapie and mastitis | Q57083648 | ||
Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes | Q57083650 | ||
Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions | Q57083652 | ||
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion | Q57083661 | ||
Cannibals and garbage piles | Q57083664 | ||
Transepithelial prion transport by M cells | Q57083694 | ||
PrP expression in B lymphocytes is not required for prion neuroinvasion | Q57083708 | ||
Ionising radiation has no influence on scrapie incubation period in mice | Q45210935 | ||
The physical basis of how prion conformations determine strain phenotypes | Q46092862 | ||
Complement protein C1q recognizes a conformationally modified form of the prion protein. | Q46377156 | ||
Pathogenesis of Scrapie in the Mouse: the Role of the Spleen | Q47670807 | ||
Passage of murine scrapie prion protein across the mouse vascular blood-brain barrier | Q47693977 | ||
Development of a human adaptive immune system in cord blood cell-transplanted mice | Q47819239 | ||
Protein-only transmission of three yeast prion strains | Q47929764 | ||
Murine scrapie infection causes an abnormal germinal centre reaction in the spleen | Q47994853 | ||
Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts | Q48038743 | ||
Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle | Q48101626 | ||
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease | Q48152236 | ||
Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie | Q48211578 | ||
Embryonic activation and developmental expression of the murine prion protein gene | Q48338009 | ||
Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly | Q48382521 | ||
NMR structure of the mouse prion protein domain PrP(121-231) | Q27733163 | ||
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells | Q28144723 | ||
The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
Mice devoid of PrP are resistant to scrapie | Q28249108 | ||
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen | Q28300225 | ||
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function | Q29617462 | ||
The nature of small-airway obstruction in chronic obstructive pulmonary disease | Q29618682 | ||
Development and maturation of secondary lymphoid tissues. | Q33652498 | ||
Topics in prion cell biology | Q33745335 | ||
Prion protein NMR structures of elk and of mouse/elk hybrids | Q33756704 | ||
Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells. | Q33844547 | ||
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells | Q33894673 | ||
A novel erythroid-specific marker of transmissible spongiform encephalopathies | Q33936308 | ||
Kuru in the 21st century--an acquired human prion disease with very long incubation periods | Q33997105 | ||
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding | Q34084209 | ||
Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics | Q34190049 | ||
Prion pathogenesis in the absence of Toll-like receptor signalling | Q34227964 | ||
Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population | Q34242490 | ||
Balancing claims for balancing selection | Q34329282 | ||
Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient | Q34339769 | ||
A new variant of Creutzfeldt-Jakob disease in the UK. | Q34374893 | ||
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. | Q34403513 | ||
Detection of prions in blood | Q34446509 | ||
Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis | Q34480339 | ||
Evidence for a functional second thymus in mice | Q34499243 | ||
Library subtraction of in vitro cDNA libraries to identify differentially expressed genes in scrapie infection | Q34580217 | ||
The most infectious prion protein particles. | Q34805737 | ||
Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway | Q34815328 | ||
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice | Q35051960 | ||
Lymphotoxin/light, lymphoid microenvironments and autoimmune disease | Q35219029 | ||
Prions and the immune system: a journey through gut, spleen, and nerves | Q35622996 | ||
Mammalian prion biology: one century of evolving concepts | Q35639302 | ||
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes | Q35749282 | ||
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein | Q35764516 | ||
Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy | Q57093007 | ||
cDNA cloning of turtle prion protein | Q58856615 | ||
Complement activation in human prion disease | Q59691562 | ||
Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo | Q61463936 | ||
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie | Q64447657 | ||
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells | Q64447658 | ||
Transmission of chronic spongiform encephalopathy with kuru plaques from humans to small rodents | Q66895954 | ||
Follicular dendritic cells in Hodgkin's disease | Q68192221 | ||
Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice | Q68951739 | ||
The role of the spleen in the neuroinvasion of scrapie in mice | Q69203477 | ||
Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens | Q70495892 | ||
Host-genotype and agent effects in scrapie incubation: Change in allelic interaction with different strains of agent | Q70727514 | ||
High level expression of Ricinus communis casbene synthase in Escherichia coli and characterization of the recombinant enzyme | Q71859005 | ||
Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein | Q71970964 | ||
Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity | Q72246984 | ||
Detection of PrPSc in lymphoid tissues of lambs experimentally exposed to the scrapie agent | Q73119639 | ||
Follicular dendritic cells: a license to tangle with scrapie | Q73247220 | ||
The immunophenotypic characterization of bovine lymphomas | Q73367789 | ||
Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie | Q73398036 | ||
Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis | Q73504538 | ||
Prp-c and Prp-Sc at the fetal-maternal interface | Q73684853 | ||
Lymphoid neogenesis in rheumatoid synovitis | Q74147962 | ||
14-3-3 protein, neuron-specific enolase, and S-100 protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease | Q74587325 | ||
PrP(Sc) deposition in nervous tissues without lymphoid tissue involvement is frequently found in ARQ/ARQ Sarda breed sheep preclinically affected with natural scrapie | Q83178031 | ||
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele | Q93870994 | ||
Antiprion immunotherapy: to suppress or to stimulate? | Q35877214 | ||
Diagnosing prion diseases: needs, challenges and hopes | Q35892062 | ||
Major histocompatibility complex genes have an increased brain expression after scrapie infection | Q36030884 | ||
Prions, cytokines, and chemokines: a meeting in lymphoid organs | Q36050784 | ||
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions | Q36161465 | ||
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie | Q36167962 | ||
Chronic inflammation caused by lymphotoxin is lymphoid neogenesis | Q36366337 | ||
Prions and their lethal journey to the brain | Q36389302 | ||
Lymphoid organ development: from ontogeny to neogenesis | Q36426808 | ||
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system | Q36688984 | ||
Follicular dendritic cells in non-Hodgkin lymphomas: Localisation, characterisation and pathophysiological aspects | Q37105341 | ||
A 'unified theory' of prion propagation | Q37257816 | ||
Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas | Q37263532 | ||
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration | Q38345478 | ||
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. | Q39321575 | ||
Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymus | Q39628890 | ||
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration | Q39646511 | ||
Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain | Q39683541 | ||
Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes | Q39714788 | ||
Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility | Q39756940 | ||
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease | Q40113593 | ||
Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface | Q40867441 | ||
Progress and problems in the biology, diagnostics, and therapeutics of prion diseases | Q41062579 | ||
Epithelial M cells: gateways for mucosal infection and immunization | Q41075139 | ||
Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria | Q41094317 | ||
Retrovirus infection strongly enhances scrapie infectivity release in cell culture | Q41445328 | ||
Scrapie-Infected Spleens: Analysis of Infectivity, Scrapie-Associated Fibrils, and Protease-Resistant Proteins | Q41876639 | ||
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene | Q41982232 | ||
Humanized mice: are we there yet? | Q42972285 | ||
Prions in skeletal muscles of deer with chronic wasting disease | Q43219831 | ||
Postexposure prophylaxis against prion disease with a stimulator of innate immunity | Q43490953 | ||
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion | Q43702721 | ||
Molecular cloning of the cDNA coding for Xenopus laevis prion protein | Q43806024 | ||
PrP(CWD) lymphoid cell targets in early and advanced chronic wasting disease of mule deer | Q44141188 | ||
Transmission of prion diseases by blood transfusion | Q44186164 | ||
Conformational variations in an infectious protein determine prion strain differences | Q44187524 | ||
The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease | Q44560871 | ||
Pathogenesis of Scrapie Virus Infection in the Mouse | Q44956310 | ||
Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infection | Q45111644 | ||
Transmission of BSE by blood transfusion in sheep | Q45186151 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | prion protein family | Q24724413 |
P304 | page(s) | 765-775 | |
P577 | publication date | 2006-10-01 | |
P1433 | published in | Nature Reviews Microbiology | Q1071797 |
P1476 | title | Pathogenesis of prion diseases: current status and future outlook | |
P478 | volume | 4 |
Q57014330 | 3D-RISM-KH approach for biomolecular modelling at nanoscale: thermodynamics of fibril formation and beyond |
Q55268338 | A quantitative characterization of interaction between prion protein with nucleic acids. |
Q37080692 | A structural overview of the vertebrate prion proteins |
Q33373345 | AA-amyloidosis can be transferred by peripheral blood monocytes |
Q21089612 | Aerosols transmit prions to immunocompetent and immunodeficient mice |
Q28539753 | Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease |
Q42091975 | All quiet on the neuronal front: NMDA receptor inhibition by prion protein |
Q57261117 | Altered lymphocyte homeostasis after oral prion infection in mouse |
Q40071129 | Analysis of miRNA Signatures in Neurodegenerative Prion Disease. |
Q56768795 | Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microglia |
Q36579822 | Antiprion prophylaxis by gene transfer of a soluble prion antagonist |
Q56740033 | Bovine spongiform encephalopathy (BSE) associated polymorphisms of the prion-like protein gene (PRND) in Korean dairy cattle and Hanwoo |
Q34146362 | CD36 participates in PrP(106-126)-induced activation of microglia |
Q34873055 | Can misfolded proteins be beneficial? The HAMLET case |
Q59029285 | Cell biology: Infectious Alzheimer's disease? |
Q37520006 | Cells and prions: a license to replicate |
Q39722913 | Changing the solvent accessibility of the prion protein disulfide bond markedly influences its trafficking and effect on cell function |
Q34629949 | Chemistry and biology of mammalian metallothioneins. |
Q37981836 | Copper-dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders. |
Q48297400 | Current strategies to prevent transmission of prions by human plasma derivatives |
Q33847248 | Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders |
Q84293672 | Development of an ultra-rapid diagnostic method based on heart-type fatty acid binding protein levels in the CSF of CJD patients |
Q36985644 | Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo |
Q33303678 | Direct detection of soil-bound prions |
Q51007413 | Enhanced neural progenitor/stem cells self-renewal via the interaction of stress-inducible protein 1 with the prion protein. |
Q38267191 | Enhancement of immunohistochemical staining of scrapie proteins and immune cells within lymph nodes of early scrapie-infected sheep |
Q35194917 | Establishment and characterization of Prnp knockdown neuroblastoma cells using dual microRNA-mediated RNA interference |
Q27026606 | Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics |
Q21129257 | Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? |
Q58696119 | Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein |
Q50878634 | FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice. |
Q39474448 | Functional genomics approach for identification of molecular processes underlying neurodegenerative disorders in prion diseases |
Q37529488 | Gene expression profiling of mesenteric lymph nodes from sheep with natural scrapie |
Q38028523 | Gene expression profiling to identify druggable targets in prion diseases. |
Q27314808 | Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila |
Q39609406 | Glycosylation of PrPC determines timing of neuroinvasion and targeting in the brain following transmissible spongiform encephalopathy infection by a peripheral route |
Q44789133 | High levels of cellular prion protein improve astrocyte development |
Q36957378 | Hydration effects on the HET-s prion and amyloid-beta fibrillous aggregates, studied with three-dimensional molecular theory of solvation |
Q64897506 | IVIG Delays Onset in a Mouse Model of Gerstmann-Sträussler-Scheinker Disease. |
Q34648779 | Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism |
Q39431937 | Implications of peptide assemblies in amyloid diseases |
Q35499246 | Infectious prion protein alters manganese transport and neurotoxicity in a cell culture model of prion disease |
Q57083613 | Introduction to Prion Disorders |
Q40413509 | Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission |
Q33838378 | Mammalian Metallothionein-3: New Functional and Structural Insights |
Q33856313 | Manganese upregulates cellular prion protein and contributes to altered stabilization and proteolysis: relevance to role of metals in pathogenesis of prion disease |
Q84414747 | Mapping the interaction site of prion protein and Sho |
Q48308847 | Molecular dynamics studies on the structural stability of wild-type dog prion protein |
Q33772925 | Mouse neuronal cells expressing exogenous bovine PRNP and simultaneous downregulation of endogenous mouse PRNP using siRNAs |
Q33425214 | Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles |
Q33631161 | Paradoxical role of prion protein aggregates in redox-iron induced toxicity |
Q42874098 | Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice |
Q44641001 | PrP 106-126 altered PrP mRNA gene expression in mouse microglia BV-2 cells |
Q28476111 | Preclinical deposition of pathological prion protein in muscle of experimentally infected primates |
Q49957320 | Prion Proteins Without the Glycophosphatidylinositol Anchor: Potential Biomarkers in Neurodegenerative Diseases |
Q37075786 | Prion diseases: from protein to cell pathology |
Q37080541 | Prion interference with multiple prion isolates |
Q42068269 | Prion pathogenesis is independent of caspase-12. |
Q44728173 | Prion protein and its ligand stress inducible protein 1 regulate astrocyte development |
Q34570047 | Prion protein in Caenorhabditis elegans: Distinct models of anti-BAX and neuropathology |
Q37087487 | Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis |
Q36895918 | Prion proteins: a biological role beyond prion diseases |
Q37162363 | Prions: Beyond a Single Protein |
Q54242204 | Prolonged follicular helper T cell responses in ME7 scrapie-infected mice. |
Q34023019 | Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate |
Q90697402 | Protein Aggregation and Dysfunction of Autophagy-Lysosomal Pathway: A Vicious Cycle in Lysosomal Storage Diseases |
Q36796856 | Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation |
Q37184038 | Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease |
Q24607278 | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells |
Q36579439 | Strain-dependent profile of misfolded prion protein aggregates |
Q45258419 | Studies on the structural stability of rabbit prion probed by molecular dynamics simulations |
Q33554002 | The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair |
Q53167444 | The catalytic redox activity of prion protein-Cu(II) is controlled by metal exchange with the Zn(II) -thiolate clusters of Zn(7) metallothionein-3. |
Q37595526 | The long term immunological response of swine after two exposures to a salmon thrombin and fibrinogen hemostatic bandage |
Q37080450 | The prion protein knockout mouse: a phenotype under challenge |
Q37326706 | The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration |
Q38511739 | The secret life of extracellular vesicles in metal homeostasis and neurodegeneration |
Q46077844 | The structural stability of wild-type horse prion protein |
Q37549830 | Therapy for prion diseases: Insights from the use of RNA interference. |
Q37779740 | Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application |
Q24289511 | Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples |
Q47368173 | Translational Research in Alzheimer's and Prion Diseases |
Q35143098 | Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation. |
Q58273929 | Variable Levels of 37-kDa/67-kDa Laminin Receptor (RPSA) mRNA in Ovine Tissues: Potential Contribution to the Regulatory Processes of PrPScPropagation? |
Q35055085 | Wound healing and the immune response in swine treated with a hemostatic bandage composed of salmon thrombin and fibrinogen |
Search more.