Pathogenesis of prion diseases: current status and future outlook

scientific article published on October 2006

Pathogenesis of prion diseases: current status and future outlook is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/NRMICRO1492
P698PubMed publication ID16980938
P5875ResearchGate publication ID6813215

P50authorAdriano AguzziQ375410
Mathias HeikenwalderQ43369827
P2860cites workA Toll-like receptor recognizes bacterial DNAQ24290668
The prion protein gene in humans revisited: lessons from a worldwide resequencing studyQ24537613
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewalQ24541459
Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanismQ24679391
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank volesQ25257725
Agent replication dynamics in a long incubation period model of mouse scrapieQ48431705
Presymptomatic detection of prions in blood.Q48477099
Selective expression of prion protein in peripheral tissues of the adult mouseQ48544898
A crucial role for B cells in neuroinvasive scrapie.Q48574532
Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheepQ48598161
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brainQ48630602
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob diseaseQ48691137
Coincident scrapie infection and nephritis lead to urinary prion excretionQ48730761
Competition between Different Scrapie Agents in MiceQ48752287
Very Early Replication of Scrapie in Lymphocytic TissueQ48882800
The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathiesQ48913771
Complement facilitates early prion pathogenesisQ48930440
Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.Q49113318
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.Q51037857
vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?Q51037865
Developmental expression of the prion protein gene in glial cellsQ52209886
Binding of disease-associated prion protein to plasminogen.Q52541671
Migrating intestinal dendritic cells transport PrP(Sc) from the gut.Q53676141
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.Q54014234
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.Q54037114
NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).Q54559823
Prion Diseases and a Penchant for BrainsQ57039333
PrPSc in mammary glands of sheep affected by scrapie and mastitisQ57083648
Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomesQ57083650
Chronic Lymphocytic Inflammation Specifies the Organ Tropism of PrionsQ57083652
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasionQ57083661
Cannibals and garbage pilesQ57083664
Transepithelial prion transport by M cellsQ57083694
PrP expression in B lymphocytes is not required for prion neuroinvasionQ57083708
Ionising radiation has no influence on scrapie incubation period in miceQ45210935
The physical basis of how prion conformations determine strain phenotypesQ46092862
Complement protein C1q recognizes a conformationally modified form of the prion protein.Q46377156
Pathogenesis of Scrapie in the Mouse: the Role of the SpleenQ47670807
Passage of murine scrapie prion protein across the mouse vascular blood-brain barrierQ47693977
Development of a human adaptive immune system in cord blood cell-transplanted miceQ47819239
Protein-only transmission of three yeast prion strainsQ47929764
Murine scrapie infection causes an abnormal germinal centre reaction in the spleenQ47994853
Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcriptsQ48038743
Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscleQ48101626
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob diseaseQ48152236
Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapieQ48211578
Embryonic activation and developmental expression of the murine prion protein geneQ48338009
Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularlyQ48382521
NMR structure of the mouse prion protein domain PrP(121-231)Q27733163
Impaired prion replication in spleens of mice lacking functional follicular dendritic cellsQ28144723
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
Mice devoid of PrP are resistant to scrapieQ28249108
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleenQ28300225
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated functionQ29617462
The nature of small-airway obstruction in chronic obstructive pulmonary diseaseQ29618682
Development and maturation of secondary lymphoid tissues.Q33652498
Topics in prion cell biologyQ33745335
Prion protein NMR structures of elk and of mouse/elk hybridsQ33756704
Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.Q33844547
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cellsQ33894673
A novel erythroid-specific marker of transmissible spongiform encephalopathiesQ33936308
Kuru in the 21st century--an acquired human prion disease with very long incubation periodsQ33997105
Sensitive detection of pathological prion protein by cyclic amplification of protein misfoldingQ34084209
Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemicsQ34190049
Prion pathogenesis in the absence of Toll-like receptor signallingQ34227964
Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native populationQ34242490
Balancing claims for balancing selectionQ34329282
Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patientQ34339769
A new variant of Creutzfeldt-Jakob disease in the UK.Q34374893
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.Q34403513
Detection of prions in bloodQ34446509
Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesisQ34480339
Evidence for a functional second thymus in miceQ34499243
Library subtraction of in vitro cDNA libraries to identify differentially expressed genes in scrapie infectionQ34580217
The most infectious prion protein particles.Q34805737
Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathwayQ34815328
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout miceQ35051960
Lymphotoxin/light, lymphoid microenvironments and autoimmune diseaseQ35219029
Prions and the immune system: a journey through gut, spleen, and nervesQ35622996
Mammalian prion biology: one century of evolving conceptsQ35639302
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytesQ35749282
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion proteinQ35764516
Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsyQ57093007
cDNA cloning of turtle prion proteinQ58856615
Complement activation in human prion diseaseQ59691562
Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in VivoQ61463936
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapieQ64447657
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cellsQ64447658
Transmission of chronic spongiform encephalopathy with kuru plaques from humans to small rodentsQ66895954
Follicular dendritic cells in Hodgkin's diseaseQ68192221
Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in miceQ68951739
The role of the spleen in the neuroinvasion of scrapie in miceQ69203477
Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleensQ70495892
Host-genotype and agent effects in scrapie incubation: Change in allelic interaction with different strains of agentQ70727514
High level expression of Ricinus communis casbene synthase in Escherichia coli and characterization of the recombinant enzymeQ71859005
Transmission of the BSE agent to mice in the absence of detectable abnormal prion proteinQ71970964
Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed HypersensitivityQ72246984
Detection of PrPSc in lymphoid tissues of lambs experimentally exposed to the scrapie agentQ73119639
Follicular dendritic cells: a license to tangle with scrapieQ73247220
The immunophenotypic characterization of bovine lymphomasQ73367789
Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapieQ73398036
Role of spleen macrophages in the clearance of scrapie agent early in pathogenesisQ73504538
Prp-c and Prp-Sc at the fetal-maternal interfaceQ73684853
Lymphoid neogenesis in rheumatoid synovitisQ74147962
14-3-3 protein, neuron-specific enolase, and S-100 protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob diseaseQ74587325
PrP(Sc) deposition in nervous tissues without lymphoid tissue involvement is frequently found in ARQ/ARQ Sarda breed sheep preclinically affected with natural scrapieQ83178031
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant alleleQ93870994
Antiprion immunotherapy: to suppress or to stimulate?Q35877214
Diagnosing prion diseases: needs, challenges and hopesQ35892062
Major histocompatibility complex genes have an increased brain expression after scrapie infectionQ36030884
Prions, cytokines, and chemokines: a meeting in lymphoid organsQ36050784
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prionsQ36161465
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapieQ36167962
Chronic inflammation caused by lymphotoxin is lymphoid neogenesisQ36366337
Prions and their lethal journey to the brainQ36389302
Lymphoid organ development: from ontogeny to neogenesisQ36426808
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous systemQ36688984
Follicular dendritic cells in non-Hodgkin lymphomas: Localisation, characterisation and pathophysiological aspectsQ37105341
A 'unified theory' of prion propagationQ37257816
Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreasQ37263532
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administrationQ38345478
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.Q39321575
Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymusQ39628890
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegenerationQ39646511
Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brainQ39683541
Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routesQ39714788
Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibilityQ39756940
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob diseaseQ40113593
Follicular dendritic cells carry MHC class II-expressing microvesicles at their surfaceQ40867441
Progress and problems in the biology, diagnostics, and therapeutics of prion diseasesQ41062579
Epithelial M cells: gateways for mucosal infection and immunizationQ41075139
Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteriaQ41094317
Retrovirus infection strongly enhances scrapie infectivity release in cell cultureQ41445328
Scrapie-Infected Spleens: Analysis of Infectivity, Scrapie-Associated Fibrils, and Protease-Resistant ProteinsQ41876639
Scrapie and cellular PrP isoforms are encoded by the same chromosomal geneQ41982232
Humanized mice: are we there yet?Q42972285
Prions in skeletal muscles of deer with chronic wasting diseaseQ43219831
Postexposure prophylaxis against prion disease with a stimulator of innate immunityQ43490953
Normal development and behaviour of mice lacking the neuronal cell-surface PrP proteinQ43522858
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasionQ43702721
Molecular cloning of the cDNA coding for Xenopus laevis prion proteinQ43806024
PrP(CWD) lymphoid cell targets in early and advanced chronic wasting disease of mule deerQ44141188
Transmission of prion diseases by blood transfusionQ44186164
Conformational variations in an infectious protein determine prion strain differencesQ44187524
The sympathetic nervous system is involved in variant Creutzfeldt-Jakob diseaseQ44560871
Pathogenesis of Scrapie Virus Infection in the MouseQ44956310
Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infectionQ45111644
Transmission of BSE by blood transfusion in sheepQ45186151
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectprion protein familyQ24724413
P304page(s)765-775
P577publication date2006-10-01
P1433published inNature Reviews MicrobiologyQ1071797
P1476titlePathogenesis of prion diseases: current status and future outlook
P478volume4

Reverse relations

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