Antidotes for poisoning by alcohols that form toxic metabolites

scientific article published on 9 November 2015

Antidotes for poisoning by alcohols that form toxic metabolites is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/BCP.12824
P932PMC publication ID4767193
P698PubMed publication ID26551875
P5875ResearchGate publication ID283639389

P2093author name stringKenneth McMartin
Dag Jacobsen
Knut Erik Hovda
P2860cites workFulminant ascending paralysis as a delayed sequela of diethylene glycol (Sterno) ingestionQ78504651
Extremely slow formate elimination in severe methanol poisoning: a fatal case reportQ80337846
Kinetics of fomepizole in pregnant ratsQ84793217
Outbreak of acute renal failure in Panama in 2006: a case-control studyQ24646767
Fomepizole for ethylene glycol and methanol poisoningQ28245655
Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?Q28262357
Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizoleQ28287715
2013 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 31st Annual ReportQ30882807
Fomepizole for the treatment of methanol poisoningQ31921338
Methanol poisoning and long term sequelae - a six years follow-up after a large methanol outbreakQ33423222
Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning.Q33840544
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study GroupQ33855295
American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc CommitteeQ33875038
Severe ethylene glycol poisoning treated wtih fomepizole (4-methylpyrazole)Q33962754
Osmol gaps revisited: normal values and limitations.Q34061735
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisoningsQ34123226
American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoningQ34148248
Severe methanol poisoning. Application of a pharmacokinetic model for ethanol therapy and hemodialysisQ34227691
Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signsQ34433918
Epidemic of pediatric deaths from acute renal failure caused by diethylene glycol poisoning. Acute Renal Failure Investigation TeamQ34465188
Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitroQ34631751
Diethylene glycol poisoningQ34991269
Medication-associated diethylene glycol mass poisoning: a review and discussion on the origin of contaminationQ34992120
What Are the Adverse Effects of Ethanol Used as an Antidote in the Treatment of Suspected Methanol Poisoning in Children?Q35122477
Long-term renal and neurologic outcomes among survivors of diethylene glycol poisoningQ35991251
Current recommendations for treatment of severe toxic alcohol poisoningsQ35997305
1987 Annual report of the American Association of Poison Control Centers National Data Collection SystemQ36455436
Acute experimental poisoning by diethylene glycol: acid base balance and histological data in male ratsQ36517621
Massive ethylene glycol ingestion treated with fomepizole alone-a viable therapeutic optionQ36549089
A systematic review of ethanol and fomepizole use in toxic alcohol ingestionsQ36616148
Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoningQ37284361
Fomepizole: a critical assessment of current dosing recommendationsQ37323969
Clinical, laboratory, diagnostic, and histopathologic features of diethylene glycol poisoning--Panama, 2006.Q38179646
Recommendations for the role of extracorporeal treatments in the management of acute methanol poisoning: a systematic review and consensus statementQ38286063
Diagnosis of toxic alcohols: limitations of present methodsQ38538412
A novel bedside diagnostic test for methanol poisoning using dry chemistry for formateQ38981864
Methanol poisoning I. The role of formic acid in the development of metabolic acidosis in the monkey and the reversal by 4-methylpyrazoleQ39074137
Metabolism of pyrazole. Structure elucidation of urinary metabolitesQ39144239
Methanol poisoning: ocular toxicity produced by formateQ39620837
Acute methyl alcohol poisoning. (A review of an outbreak of 89 cases)Q40065273
Czech mass methanol outbreak 2012: epidemiology, challenges and clinical featuresQ40231013
Long-term visual damage after acute methanol poisonings: Longitudinal cross-sectional study in 50 patients.Q40312820
Standardized treatment of severe methanol poisoning with ethanol and hemodialysisQ40347959
Methanol half-life during ethanol administration: implications for management of methanol poisoning.Q40449296
Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreakQ40799398
Non-linear kinetics of 4-methylpyrazole in healthy human subjects.Q41896817
Fluctuations in serum ethanol concentration in the treatment of acute methanol poisoning: a prospective study of 21 patients.Q42158081
Methanol mass poisoning in Iran: role of case finding in outbreak management.Q42209860
Role of tissue metabolite accumulation in the renal toxicity of diethylene glycolQ42728584
Inhibition of metabolism of diethylene glycol prevents target organ toxicity in ratsQ43041981
Renal toxicity of ethylene glycol results from internalization of calcium oxalate crystals by proximal tubule cellsQ43237329
Treatment of acute methanol poisoning with fomepizole.Q43712089
Childhood methanol ingestion treated with fomepizole and hemodialysisQ43753684
Oral administration of fomepizole produces similar blood levels as identical intravenous doseQ43938790
Epidemic Methanol Poisoning: Clinical and Biochemical Analysis of a Recent EpisodeQ44032941
Ethanol therapy for methanol poisoning: duration and problemsQ44190351
Inhalational methanol toxicity in pregnancy treated twice with fomepizoleQ44312977
Methanol contamination of Romanian home-distilled alcoholQ44368046
An epidemic of antifreeze poisoningQ44590192
Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patientsQ44969379
Treatment of severe pediatric ethylene glycol intoxication without hemodialysisQ45054996
Effect of ethanol on ethylene glycol oxidation by mammalian liver enzymes.Q45175568
The pharmacokinetics of methanol in the presence of ethanol: a case studyQ46089431
Ethanol: tastes great! Fomepizole: less filling!Q46262626
Delayed neurologic sequelae resulting from epidemic diethylene glycol poisoningQ46498085
Methanol and formate kinetics during treatment with fomepizoleQ46611672
Increased serum formate in the diagnosis of methanol poisoningQ46707619
Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven casesQ46714203
Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes--a multicenter study.Q46876693
Methanol mass poisoning in Estonia: outbreak in 154 patientsQ48239106
Ethylene glycol poisoning: experiences from an epidemic in SwedenQ48583901
Studies on ethylene glycol poisoning: one patient - 154 admissionsQ48810064
Massive ethylene glycol poisoning triggers osmotic demyelination syndromeQ48916549
Studies on ethylene glycol poisoning.Q49041237
Kinetics and metabolism of fomepizole in healthy humans.Q51372194
Hemodialysis for methanol intoxication.Q52108873
The osmolal gap in renal failure.Q52706887
Acetone in diabetic ketoacidosis.Q53942402
The use of an ethanol- and phosphate-enriched dialysate to maintain stable serum ethanol levels during haemodialysis for methanol intoxication.Q54207998
Methanol metabolism in the monkeyQ54403252
Fomepizole in treatment of uncomplicated ethylene glycol poisoning.Q55033287
Human liver alcohol dehydrogenase: inhibition by pyrazole and pyrazole analogsQ68598844
Increased osmolal gap in alcoholic ketoacidosis and lactic acidosisQ68919383
Comparison of the effects of ethanol and 4-methylpyrazole on the pharmacokinetics and toxicity of ethylene glycol in the dogQ69767529
Clinical Studies of Alcoholic KetoacidosisQ69767845
Considerations for the treatment of ethylene glycol poisoning based on analysis of two casesQ70191173
Studies on methanol poisoningQ70467613
Glycolate causes the acidosis in ethylene glycol poisoning and is effectively removed by hemodialysisQ70728199
Pulmonary excretion of methanol in manQ71117693
4-methylpyrazole monitoring during haemodialysis of ethylene glycol intoxicated patientsQ71149790
Ethylene glycol poisoning: pharmacokinetics during therapy with ethanol and hemodialysisQ71373094
Studies on the metabolic interactions between 4-methylpyrazole and methanol using the monkey as an animal modelQ71496472
4-Methylpyrazole (4-MP) is effectively removed by haemodialysis in the pig modelQ71503362
Predictive value of serum osmolality in shock following major traumaQ71688526
Osmolal and anion gaps in patients admitted to an emergency medical departmentQ72674286
Intravenous 4-methylpyrazole as an antidote for diethylene glycol and triethylene glycol poisoning: a case reportQ73000982
Methanol poisoning during late pregnancyQ73272791
Osmolal gap in alcoholic ketoacidosisQ73566030
Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysisQ73740110
Treatment of acute methanol intoxication with hemodialysis using an ethanol-enriched, bicarbonate-based dialysateQ73782151
Preparation of ethanol-enriched, bicarbonate-based hemodialysatesQ74459821
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)505-515
P577publication date2015-11-09
P1433published inBritish Journal of Clinical PharmacologyQ176044
P1476titleAntidotes for poisoning by alcohols that form toxic metabolites
P478volume81

Reverse relations

cites work (P2860)
Q93008884Acute toxic kidney injury
Q37322623Case Report of a Fatal Antifreeze Ingestion with a Record High Level and Impressive Renal Crystal Deposition.
Q90429601Early dialysis in a rare case of combined toxic alcohols ingestion
Q38668658Intermittent versus continuous renal replacement therapy in acute methanol poisoning: comparison of clinical effectiveness in mass poisoning outbreaks
Q89481558Methanol as an Unlisted Ingredient in Supposedly Alcohol-Based Hand Rub Can Pose Serious Health Risk
Q40273035Positive serum ethanol concentration on admission to hospital as the factor predictive of treatment outcome in acute methanol poisoning
Q92606177The Diagnosis and Management of Toxic Alcohol Poisoning in the Emergency Department: A Review Article
Q35974818The Methanol Poisoning Outbreaks in Libya 2013 and Kenya 2014
Q42591705Therapeutics in clinical toxicology: in the absence of strong evidence how do we choose between antidotes, supportive care and masterful inactivity
Q50089562Toxic alcohol diagnosis and management: an emergency medicine review

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