DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor

scientific article published on 18 February 2013

DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...856869M
P356DOI10.1371/JOURNAL.PONE.0056869
P932PMC publication ID3575498
P698PubMed publication ID23441222
P5875ResearchGate publication ID235730776

P50authorShlomo WagnerQ37838185
P2093author name stringHarold Gainer
Liza Barki-Harrington
Rapita Sood
Hadar Shahar-Gold
Shimrat Mamrut
Hala Harony
Yi-Jun Shi
P2860cites workGenomic and epigenetic evidence for oxytocin receptor deficiency in autismQ21245265
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Oxytocin and experimental therapeutics in autism spectrum disordersQ28288567
Covalent modification of DNA regulates memory formationQ28576256
ERK2 mediates oxytocin-stimulated PGE2 synthesisQ28582779
The proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to g(q), but not g(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular storesQ28583525
The mammalian epigenomeQ29615763
DNA methylation landscapes: provocative insights from epigenomicsQ29617144
Structure and expression of the mouse oxytocin receptor geneQ30426451
Defective oxytocin function: a clue to understanding the cause of autism?Q33511680
Bovine endometrial epithelial cells as a model system to study oxytocin receptor regulationQ33535275
The role of sex steroids in the oxytocin hormone systemQ33690335
The role of epigenetic transcription repression and DNA methyltransferases in cancer.Q33718270
CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expressionQ33726245
The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behaviorQ33761364
The structure and regulation of the oxytocin receptorQ34295342
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Oxytocin, vasopressin and pair bonding: implications for autismQ34583424
Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexesQ34669282
5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapyQ34770609
Molecular regulation of the oxytocin receptor in peripheral organsQ35102785
DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoterQ35809619
Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF ) after acute psychosocial stress.Q36203425
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathwaysQ36970038
The role of Sp1 and Sp3 in normal and cancer cell biologyQ37784574
The contribution of oxytocin and vasopressin to mammalian social behavior: potential role in autism spectrum disorderQ37819758
Neuronal activity modifies the DNA methylation landscape in the adult brainQ38594616
Surface plasmon resonance study of cooperative interactions of estrogen receptor alpha and transcriptional factor Sp1 with composite DNA elementsQ39866613
Oxytocin Receptors: Triggers for Parturition and Lactation?Q40234281
Oxytocin and oxytocin receptor gene expression in the uterusQ40519056
Cloning, novel promoter sequence, and estrogen regulation of a rat oxytocin receptor geneQ42435130
Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements.Q42485846
Oxytocin receptor gene expression in rat mammary gland: structural characterization and regulationQ43743158
DNA methylation of the human oxytocin receptor gene promoter regulates tissue-specific gene suppressionQ43810854
Extracellular signal-regulated kinase 1/2 activation by myometrial oxytocin receptor involves Galpha(q)Gbetagamma and epidermal growth factor receptor tyrosine kinase activationQ44480609
Expression and region-specific regulation of the oxytocin receptor gene in rat brainQ48723098
Effects of estrogen on oxytocin receptor messenger ribonucleic acid expression in the uterus, pituitary, and forebrain of the female rat.Q48809799
DNA Methylation and CancerQ57239860
Oxytocin receptors in rat involuting mammary glandQ70168521
Oxytocin receptor gene expression in the rat uterus during pregnancy and the estrous cycle and in response to gonadal steroid treatmentQ71813148
Site-directed mutagenesis of double-stranded DNA by the polymerase chain reactionQ72427121
Oestradiol regulation of oxytocin receptor expression in cyclic bovine endometriumQ73919469
Sp1 binding sites and an estrogen response element half-site are involved in regulation of the human progesterone receptor A promoterQ73998131
A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppressionQ74250785
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectoxytocinQ169960
DNA methylationQ874745
P304page(s)e56869
P577publication date2013-02-18
P1433published inPLOS OneQ564954
P1476titleDNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor
P478volume8

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cites work (P2860)
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