scholarly article | Q13442814 |
P50 | author | Kirit Pindolia | Q42766691 |
P2093 | author name string | Sahn-Ho Kim | |
Yongbo Liu | |||
Subhash C Gautam | |||
Xiaohua Gao | |||
Ali S Arbab | |||
Dorrah Deeb | |||
P2860 | cites work | hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization | Q24310670 |
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells | Q24598974 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
On the road to immortality: hTERT upregulation in cancer cells | Q28257238 | ||
The RNA component of human telomerase | Q28288330 | ||
A survey of telomerase activity in human cancer | Q29614858 | ||
Beginning to understand the end of the chromosome | Q30312045 | ||
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines | Q33631239 | ||
Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer. | Q34332428 | ||
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms | Q34369723 | ||
Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179. | Q34568528 | ||
Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling | Q34913859 | ||
The significance of telomerase activation and cellular immortalization in human cancer | Q34999777 | ||
Evolving views of telomerase and cancer | Q35147354 | ||
Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer | Q35234294 | ||
Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells | Q35688777 | ||
Regulation of telomerase activity in immortal cell lines | Q36560197 | ||
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death | Q36742412 | ||
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. | Q36796876 | ||
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms | Q37368068 | ||
Chromosome first aid. | Q37430022 | ||
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). | Q38316509 | ||
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor | Q39376059 | ||
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice | Q40158424 | ||
Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling | Q40158789 | ||
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells | Q40314340 | ||
Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells. | Q40390493 | ||
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia | Q40497248 | ||
The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism | Q43578278 | ||
Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling | Q44370211 | ||
Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines | Q44817156 | ||
The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells | Q46523672 | ||
Telomerase activity in human germline and embryonic tissues and cells | Q49024139 | ||
The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling | Q53555135 | ||
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation | Q73322990 | ||
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit | Q77388144 | ||
Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors | Q77995579 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pancreatic cancer | Q212961 |
P304 | page(s) | 561-567 | |
P577 | publication date | 2012-05-16 | |
P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
P1476 | title | Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity | |
P478 | volume | 422 |
Q92237902 | Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review |
Q38736995 | Aphanin, a triterpenoid from Amoora rohituka inhibits K-Ras mutant activity and STAT3 in pancreatic carcinoma cells |
Q34415403 | Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties |
Q27002903 | Broad targeting of angiogenesis for cancer prevention and therapy |
Q38807055 | CDDO and Its Role in Chronic Diseases. |
Q53596121 | Dose-dependent cytotoxic effects of boldine in HepG-2 cells-telomerase inhibition and apoptosis induction. |
Q38903062 | Downregulation of telomerase activity by diclofenac and curcumin is associated with cell cycle arrest and induction of apoptosis in colon cancer |
Q34302954 | Gene therapy in pancreatic cancer |
Q36144711 | Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. |
Q35680729 | Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells |
Q34069749 | Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways |
Q36783439 | Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent |
Q37731917 | Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence. |
Q38817363 | Oleanolic acid derivatives for pharmaceutical use: a patent review |
Q41820952 | Oleanolic acid derivatives induce apoptosis in human leukemia K562 cell involved in inhibition of both Akt1 translocation and pAkt1 expression |
Q21245749 | Preclinical evidences toward the use of triterpenoid CDDO-Me for solid cancer prevention and treatment |
Q47265475 | Telomerase Inhibitors from Natural Products and Their Anticancer Potential |
Q36715258 | Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer |
Q42114458 | Time Course Expression Analysis of 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole Induction of Cytoprotection in Human Endothelial Cells |
Q38129642 | Triterpenoids as reversal agents for anticancer drug resistance treatment |
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