Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge

scientific article published on October 1, 1994

Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.68.10.6578-6588.1994
P953full work available at URLhttps://jvi.asm.org/content/jvi/68/10/6578.full.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7521918/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7521918/pdf/?tool=EBI
http://jvi.asm.org/cgi/content/abstract/68/10/6578
https://europepmc.org/articles/PMC237078
https://europepmc.org/articles/PMC237078?pdf=render
https://journals.asm.org/doi/pdf/10.1128/jvi.68.10.6578-6588.1994
P932PMC publication ID237078
P698PubMed publication ID7521918

P2093author name stringD. C. Montefiori
M. Mancini
P. Tiollais
M. L. Michel
Y. Rivière
K. Schlienger
P2860cites workMacrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 geneQ41699910
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Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccinesQ36630114
Immune response of rhesus macaques to recombinant simian immunodeficiency virus gp130 does not protect from challenge infection.Q36640342
Both the V2 and V3 regions of the human immunodeficiency virus type 1 surface glycoprotein functionally interact with other envelope regions in syncytium formationQ36647416
Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.Q36649240
Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeysQ36650125
Probing the structure of the V2 domain of human immunodeficiency virus type 1 surface glycoprotein gp120 with a panel of eight monoclonal antibodies: human immune response to the V1 and V2 domainsQ36653730
Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120Q36690500
Characterization of B-Cell Epitopes in the Envelope Glycoproteins of Simian Immunodeficiency VirusQ36695972
Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees.Q36812220
Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteinsQ36827554
The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1Q36839199
Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndromeQ36860939
Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challengeQ36886112
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Protection of macaques with a simian immunodeficiency virus envelope peptide vaccine based on conserved human immunodeficiency virus type 1 sequencesQ37577555
Synthesis in animal cells of hepatitis B surface antigen particles carrying a receptor for polymerized human serum albuminQ37579934
Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibodyQ37603996
Functional role of the V1/V2 region of human immunodeficiency virus type 1 envelope glycoprotein gp120 in infection of primary macrophages and soluble CD4 neutralization.Q39143639
T- and B-lymphocyte responses to human immunodeficiency virus (HIV) type 1 in macaques immunized with hybrid HIV/hepatitis B surface antigen particlesQ40109002
Macrophage tropism determinants of human immunodeficiency virus type 1 in vivoQ40308974
Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodiesQ41621929
Production and of monoclonal antibodies to simian immunodeficiency virus envelope glycoproteinsQ41677477
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectSimian immunodeficiency virusQ1890246
P304page(s)6578-6588
P577publication date1994-10-01
P1433published inJournal of VirologyQ1251128
P1476titleVaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge
P478volume68

Reverse relations

cites work (P2860)
Q39879382Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals.
Q39577967Delayed infection after immunization with a peptide from the transmembrane glycoprotein of the feline immunodeficiency virus
Q35839932Enhancement of feline immunodeficiency virus infection after immunization with envelope glycoprotein subunit vaccines
Q39642374Identification of highly attenuated mutants of simian immunodeficiency virus
Q35897786Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virus.
Q33852720Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors
Q35838430Sequence diversity of V1 and V2 domains of gp120 from human immunodeficiency virus type 1: lack of correlation with viral phenotype.
Q33810277Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus
Q39874667Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.
Q35848231Vaccine-induced virus-neutralizing antibodies and cytotoxic T cells do not protect macaques from experimental infection with simian immunodeficiency virus SIVmac32H (J5)
Q39591825Variability and immunogenicity of caprine arthritis-encephalitis virus surface glycoprotein

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