review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Aguan Wei | |
Lawrence Salkoff | |||
Alice Butler | |||
Gonzalo Ferreira | |||
Celia Santi | |||
P2860 | cites work | Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog | Q22009115 |
Cloning and functional expression of two families of beta-subunits of the large conductance calcium-activated K+ channel | Q22253909 | ||
A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin | Q22254019 | ||
Cloning, expression, and distribution of functionally distinct Ca(2+)-activated K+ channel isoforms from human brain | Q24310769 | ||
Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel | Q24311958 | ||
A novel calcium-sensing domain in the BK channel | Q24532903 | ||
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency | Q24563081 | ||
A family of potassium channel genes related to eag in Drosophila and mammals | Q24563554 | ||
Large conductance voltage- and calcium-dependent K+ channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus | Q24617750 | ||
The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting states | Q24642378 | ||
Gating mechanism of BK (Slo1) channels: so near, yet so far | Q24644547 | ||
Gating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH(2)- and COOH termini | Q24653429 | ||
Crystal structure and mechanism of a calcium-gated potassium channel | Q27639064 | ||
Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit | Q28144481 | ||
A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans | Q28191512 | ||
Cloning and characterization of human and mouse homologs of the Drosophila calcium-activated potassium channel gene, slowpoke | Q28242311 | ||
Genetic modification of potassium channels in Drosophila Shaker mutants | Q28264139 | ||
Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel | Q28289958 | ||
mSlo , a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels | Q28298176 | ||
Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel | Q28507619 | ||
The sodium-activated potassium channel is encoded by a member of the Slo gene family | Q28570518 | ||
Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release | Q28573459 | ||
Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP | Q28574688 | ||
Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice | Q28593899 | ||
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss | Q28595088 | ||
Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes | Q28609289 | ||
Alternative splicing of potassium channels: a dynamic switch of cellular excitability. | Q30328570 | ||
Mechanisms of hair cell tuning | Q33547276 | ||
Molecular basis for the inactivation of Ca2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells | Q33865667 | ||
hKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calcium-activated potassium channel beta subunit family | Q33903332 | ||
Rectification and rapid activation at low Ca2+ of Ca2+-activated, voltage-dependent BK currents: consequences of rapid inactivation by a novel beta subunit. | Q33906724 | ||
SLO-2, a K+ channel with an unusual Cl- dependence | Q33910474 | ||
Opening and closing transitions for BK channels often occur in two steps via sojourns through a brief lifetime subconductance state | Q34019526 | ||
Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+. | Q34038735 | ||
Modeling hair cell tuning by expression gradients of potassium channel beta subunits | Q34179631 | ||
Functional role of the β subunit of high conductance calcium-activated potassium channels | Q34307062 | ||
Protein kinases: tuners of the BKCa channel in smooth muscle. | Q34389011 | ||
Opposite regulation of Slick and Slack K+ channels by neuromodulators. | Q34524090 | ||
Modulation of calcium-activated potassium channels. | Q34580307 | ||
A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification | Q35171476 | ||
Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation | Q35313534 | ||
Calcium-activated potassium channels: multiple contributions to neuronal function. | Q35738854 | ||
Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels | Q35918554 | ||
Reconstitution in planar lipid bilayers of a Ca2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle | Q36280150 | ||
Intra- and intersubunit cooperativity in activation of BK channels by Ca2+ | Q36295837 | ||
Dendritic control of spontaneous bursting in cerebellar Purkinje cells. | Q47798394 | ||
Na+-activated K+ channels in small dorsal root ganglion neurones of rat. | Q47858801 | ||
Electrophysiological properties of BK channels in Xenopus motor nerve terminals | Q47870928 | ||
Control of alternative splicing of potassium channels by stress hormones. | Q48038386 | ||
Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochlea | Q48042092 | ||
Molecular constituents of maxi KCa channels in human coronary smooth muscle: predominant alpha + beta subunit complexes | Q48046480 | ||
The Drosophila erg K+ channel polypeptide is encoded by the seizure locus | Q48054809 | ||
Ionic Mechanisms of Burst Firing in Dissociated Purkinje Neurons | Q48164908 | ||
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels | Q48181699 | ||
A Component of Calcium-activated Potassium Channels Encoded by the Drosophila slo Locus | Q48215777 | ||
K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse | Q48267286 | ||
Molecular analysis of the para locus, a sodium channel gene in Drosophila | Q48287063 | ||
Properties and modulation of a calcium-activated potassium channel in rat olfactory bulb neurons | Q48293481 | ||
Selective activation of Ca2+-activated K+ channels by co-localized Ca2+ channels in hippocampal neurons | Q48357057 | ||
Localization of the Slack potassium channel in the rat central nervous system | Q48443004 | ||
Somatostatin stimulates Ca2+-activated K+ channels through protein dephosphorylation | Q48707748 | ||
Na(+)-activated K+ channels and voltage-evoked ionic currents in brain stem and parasympathetic neurones of the chick | Q48761480 | ||
Electrostatic tuning of ion conductance in potassium channels | Q48824034 | ||
Localization of the Na+-activated K+ channel Slick in the rat central nervous system | Q49038111 | ||
Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals | Q49158543 | ||
Mechanism of magnesium activation of calcium-activated potassium channels. | Q50486860 | ||
Differential distribution of Ca2+-activated K+ channel splice variants among hair cells along the tonotopic axis of the chick cochlea. | Q50507448 | ||
A large, sustained Na(+)- and voltage-dependent K+ current in spinal neurons of the frog embryo. | Q51671064 | ||
A Na+-activated K+ current in cultured brain stem neurones from chicks. | Q51755915 | ||
Long-lasting reduction of excitability by a sodium-dependent potassium current in cat neocortical neurons. | Q51756970 | ||
Sodium-activated potassium current in cultured avian neurones. | Q51820645 | ||
Allosteric linkage between voltage and Ca(2+)-dependent activation of BK-type mslo1 K(+) channels. | Q53900509 | ||
Intracellular Na+ activates a K+ channel in mammalian cardiac cells | Q53910978 | ||
A family of calcium-dependent potassium channels from rat brain. | Q54116987 | ||
Single channel recordings of Ca2+-activated K+ currents in rat muscle cell culture | Q59070211 | ||
Ca-dependent K channels with large unitary conductance in chromaffin cell membranes | Q59070332 | ||
Potassium conductance and internal calcium accumulation in a molluscan neurone | Q70767680 | ||
Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels | Q71623113 | ||
Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release | Q72096278 | ||
Properties and functions of Na(+)-activated K+ channels in the soma of rat motoneurones | Q72998029 | ||
Alternative splicing switches potassium channel sensitivity to protein phosphorylation | Q73598864 | ||
Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits | Q77299369 | ||
Transplantable sites confer calcium sensitivity to BK channels | Q77732702 | ||
Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones | Q44788685 | ||
Neurobiology of the Caenorhabditis elegans genome. | Q46229602 | ||
Vasoregulation by the beta1 subunit of the calcium-activated potassium channel | Q46410172 | ||
Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel | Q46601467 | ||
SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction | Q47068866 | ||
Slob, a novel protein that interacts with the Slowpoke calcium-dependent potassium channel | Q47071447 | ||
Ligand-dependent activation of Slo family channels is defined by interchangeable cytosolic domains. | Q47332663 | ||
Kinetic structure of large-conductance Ca2+-activated K+ channels suggests that the gating includes transitions through intermediate or secondary states. A mechanism for flickers. | Q36412088 | ||
Allosteric gating of a large conductance Ca-activated K+ channel | Q36435872 | ||
Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels | Q36436425 | ||
Voltage and Ca2+ activation of single large-conductance Ca2+-activated K+ channels described by a two-tiered allosteric gating mechanism. | Q36436726 | ||
Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part I: Aspartate 292 modulates K+ conduction by external surface charge effect | Q36436751 | ||
Gating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanism | Q36436804 | ||
Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+) | Q36438968 | ||
Allosteric voltage gating of potassium channels II. Mslo channel gating charge movement in the absence of Ca(2+). | Q36438973 | ||
Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism | Q36442920 | ||
Role of the beta1 subunit in large-conductance Ca(2+)-activated K(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity | Q36444716 | ||
Allosteric regulation of BK channel gating by Ca(2+) and Mg(2+) through a nonselective, low affinity divalent cation site | Q36445217 | ||
Intracellular Mg(2+) enhances the function of BK-type Ca(2+)-activated K(+) channels | Q36445229 | ||
Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites. | Q36445694 | ||
Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity | Q36447158 | ||
Mapping the BKCa channel's "Ca2+ bowl": side-chains essential for Ca2+ sensing | Q36447234 | ||
Probing the geometry of the inner vestibule of BK channels with sugars | Q36493494 | ||
Heme regulates allosteric activation of the Slo1 BK channel | Q36493650 | ||
Gating and ionic currents reveal how the BKCa channel's Ca2+ sensitivity is enhanced by its beta1 subunit | Q36493685 | ||
Na(+)-activated K+ channels: a new family of large-conductance ion channels | Q36675358 | ||
CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels | Q36951665 | ||
A Drosophila mutation that eliminates a calcium-dependent potassium current | Q37406521 | ||
Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. | Q37416395 | ||
From the gene to behavior | Q40003245 | ||
Linker-gating ring complex as passive spring and Ca(2+)-dependent machine for a voltage- and Ca(2+)-activated potassium channel | Q40548453 | ||
Calcium activation of BK(Ca) potassium channels lacking the calcium bowl and RCK domains. | Q40685545 | ||
A molecular switch for specific stimulation of the BKCa channel by cGMP and cAMP kinase | Q40784958 | ||
Contribution of potential EF hand motifs to the calcium-dependent gating of a mouse brain large conductance, calcium-sensitive K(+) channel | Q40798532 | ||
High-conductance calcium-activated potassium channels in rat brain: pharmacology, distribution, and subunit composition | Q40958112 | ||
A molecular mechanism for electrical tuning of cochlear hair cells | Q40982781 | ||
Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila | Q41250216 | ||
Intracellular injection of a Ca2+ chelator inhibits spike repolarization in hippocampal neurons | Q41386884 | ||
Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004. | Q41470561 | ||
Unique inner pore properties of BK channels revealed by quaternary ammonium block | Q41814038 | ||
BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus | Q42458933 | ||
Calcium-activated potassium channels expressed from cloned complementary DNAs | Q42607323 | ||
Accounting for the Ca(2+)-dependent kinetics of single large-conductance Ca(2+)-activated K+ channels in rat skeletal muscle | Q42620252 | ||
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder | Q42658736 | ||
Calcium sensitivity of BK-type KCa channels determined by a separable domain. | Q42693243 | ||
Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle | Q42705857 | ||
Expression of ion channels and mutational effects in giant Drosophila neurons differentiated from cell division-arrested embryonic neuroblasts | Q43567940 | ||
Control of the delayed outward potassium currents in bursting pace-maker neurones of the snail, Helix pomatia | Q43589929 | ||
Multiple regulatory sites in large-conductance calcium-activated potassium channels. | Q44111941 | ||
Properties and rundown of sodium-activated potassium channels in rat olfactory bulb neurons | Q44352247 | ||
Na(+)-activated K+ current in cardiac cells: rectification, open probability, block and role in digitalis toxicity | Q44457213 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | potassium | Q703 |
large conductance calcium-activated potassium channel activity | Q21113513 | ||
P304 | page(s) | 921-931 | |
P577 | publication date | 2006-12-01 | |
P1433 | published in | Nature Reviews Neuroscience | Q2108225 |
P1476 | title | High-conductance potassium channels of the SLO family | |
P478 | volume | 7 |
Q47839771 | +mRNA expression of LRRC55 protein (leucine-rich repeat-containing protein 55) in the adult mouse brain |
Q33702537 | A BK (Slo1) channel journey from molecule to physiology |
Q33957044 | A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. |
Q28582966 | A conserved serine of heterogeneous nuclear ribonucleoprotein L (hnRNP L) mediates depolarization-regulated alternative splicing of potassium channels |
Q43103231 | A less flexible BK channel opens more easily |
Q34066665 | A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function. |
Q39896013 | A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel |
Q30499546 | A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans |
Q35117041 | A single fear-inducing stimulus induces a transcription-dependent switch in synaptic AMPAR phenotype |
Q42042690 | A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2). |
Q44943630 | A voltage-dependent K+ channel in the lysosome is required for refilling lysosomal Ca2+ stores. |
Q36498545 | Acid-sensing ion channels interact with and inhibit BK K+ channels |
Q34251407 | Action of molecular switches in GPCRs--theoretical and experimental studies. |
Q36965903 | Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains |
Q43062972 | Activation of endothelial BKCa channels causes pulmonary vasodilation. |
Q24338754 | Activation of galanin receptor 2 stimulates large conductance Ca(2+)-dependent K(+) (BK) channels through the IP3 pathway in human embryonic kidney (HEK293) cells |
Q41788424 | Activation of lysophosphatidic Acid receptor is coupled to enhancement of ca(2+)-activated potassium channel currents |
Q34568560 | Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells |
Q37383662 | Acute alcohol action and desensitization of ligand-gated ion channels |
Q43115553 | Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels. |
Q33701962 | Aging increases capacitance and spontaneous transient outward current amplitude of smooth muscle cells from murine superior epigastric arteries |
Q37385468 | Alcohol modulation of BK channel gating depends on β subunit composition |
Q28536909 | Alcohol-induced histone acetylation reveals a gene network involved in alcohol tolerance |
Q43826346 | Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion |
Q42597137 | Amino-termini isoforms of the Slack K+ channel, regulated by alternative promoters, differentially modulate rhythmic firing and adaptation |
Q33834949 | An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel. |
Q27346623 | An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans |
Q90759165 | Analyzing the functional divergence of Slo1 and Slo3 channel subfamilies |
Q33843357 | Anatomic and Physiologic Heterogeneity of Subgroup-A Auditory Sensory Neurons in Fruit Flies |
Q34357787 | Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels |
Q35931413 | Anthelmintics: The best way to predict the future is to create it. |
Q35817109 | Apical maxi-K (KCa1.1) channels mediate K+ secretion by the mouse submandibular exocrine gland |
Q38404580 | Are big potassium-type Ca(2+)-activated potassium channels a viable target for the treatment of epilepsy? |
Q96769244 | Aromatic interactions with membrane modulate human BK channel activation |
Q35572521 | BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells |
Q36603651 | BK Channels in Cardiovascular Diseases and Aging |
Q34088616 | BK channel activation: structural and functional insights |
Q34311824 | BK channel activators and their therapeutic perspectives |
Q36973985 | BK channels in microglia are required for morphine-induced hyperalgesia. |
Q26830341 | BK channels: multiple sensors, one activation gate |
Q42508404 | BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. |
Q46302314 | BK β1 subunit-dependent facilitation of ethanol inhibition of BK current and cerebral artery constriction is mediated by the β1 transmembrane domain 2. |
Q24311599 | BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells |
Q47110479 | BKIP-1, an auxiliary subunit critical to SLO-1 function, inhibits SLO-2 potassium channel in vivo. |
Q39707555 | BKbeta1 subunits contribute to BK channel diversity in rat hypothalamic neurons. |
Q35994501 | Basolateral membrane K+ channels in renal epithelial cells |
Q34785622 | Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons |
Q39710047 | Bilirubin oxidation end products directly alter K+ channels important in the regulation of vascular tone |
Q34308192 | Bio-inspired voltage-dependent calcium channel blockers |
Q39007250 | C-terminus of human BKca channel alpha subunit enhances the permeability of the brain endothelial cells by interacting with caveolin-1 and triggering caveolin-1 intracellular trafficking |
Q37972853 | CO metabolism, sensing, and signaling |
Q37291610 | CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits |
Q30362741 | CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis. |
Q28296117 | Ca2+-Activated K+Channels: From Protein Complexes to Function |
Q37165957 | Ca2+-activated K+ channels in gonadotropin-releasing hormone-stimulated mouse gonadotrophs |
Q35549225 | Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implications |
Q36087911 | Calcium ions open a selectivity filter gate during activation of the MthK potassium channel |
Q34322207 | Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain |
Q30480811 | Calcium-activated potassium (BK) channels are encoded by duplicate slo1 genes in teleost fishes. |
Q33680449 | Calcium-activated potassium channels BK and IK1 are functionally expressed in human gliomas but do not regulate cell proliferation |
Q54090250 | Calcium-activated potassium channels as potential early markers of human cervical cancer. |
Q51232178 | Calcium-gated K+ channels of the KCa1.1- and KCa3.1-type couple intracellular Ca2+ signals to membrane hyperpolarization in mesenchymal stromal cells from the human adipose tissue. |
Q36813857 | Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning. |
Q35810755 | Cell excitability necessary for male mating behavior in Caenorhabditis elegans is coordinated by interactions between big current and ether-a-go-go family K(+) channels |
Q36363337 | Cell-specific regulation of L-WNK1 by dietary K. |
Q28572738 | Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent |
Q37732004 | Channelopathies linked to plasma membrane phosphoinositides. |
Q37575294 | Characteristics of single large-conductance Ca2+-activated K+ channels and their regulation of action potentials and excitability in parasympathetic cardiac motoneurons in the nucleus ambiguus |
Q47789866 | Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy. |
Q28751698 | Characterization of a stretch-activated potassium channel in chondrocytes |
Q37705156 | Cholesterol and ion channels |
Q35048791 | Cholesterol down-regulates BK channels stably expressed in HEK 293 cells |
Q34131918 | Cloning and distribution of Ca2+-activated K+ channels in lobster Panulirus interruptus. |
Q39853344 | Coexpression and characterization of the human large-conductance Ca(2+)-activated K (+) channel alpha + beta1 subunits in HEK293 cells |
Q37689603 | Colonic potassium handling. |
Q39823257 | Comparative effects of H+ and Ca2+ on large-conductance Ca2+- and voltage-gated Slo1 K+ channels |
Q36405694 | Control of alternative pre-mRNA splicing by Ca(++) signals. |
Q33814269 | Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+. |
Q27674641 | Crystal Structure of a Ba2+-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation |
Q35123192 | Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region. |
Q33318188 | Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons |
Q48460762 | Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice. |
Q42822550 | Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives |
Q40297648 | Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain. |
Q37373496 | Differential regulation of action potentials by inactivating and noninactivating BK channels in rat adrenal chromaffin cells. |
Q36741209 | Direct regulation of BK channels by phosphatidylinositol 4,5-bisphosphate as a novel signaling pathway |
Q21128796 | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel |
Q36497774 | Distinct sensitivity of slo1 channel proteins to ethanol |
Q34551128 | Distribution of high-conductance calcium-activated potassium channels in rat vestibular epithelia |
Q26766001 | Diversity of Potassium Channel Ligands: Focus on Scorpion Toxins |
Q33320921 | Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy |
Q50316621 | Down-regulation of the large conductance Ca(2+)-activated K(+) channel expression in C57BL/6J cochlea |
Q33999180 | Dual-pore glass chips for cell-attached single-channel recordings |
Q37214730 | Duration differences of corticostriatal responses in striatal projection neurons depend on calcium activated potassium currents |
Q87345457 | Effects of Ca2+-activated potassium and inward rectifier potassium channel on the differentiation of endothelial progenitor cells from human peripheral blood |
Q92069491 | Effects of Single Nucleotide Polymorphisms in Human KCNMA1 on BK Current Properties |
Q33841023 | Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder |
Q39910816 | Effects of manipulating slowpoke calcium-dependent potassium channel expression on rhythmic locomotor activity in Drosophila larvae |
Q33958421 | Emerging role of the KCNT1 Slack channel in intellectual disability |
Q35685629 | Emodepside and SL0-1 potassium channels: a review. |
Q27319989 | Epilepsy-Related Slack Channel Mutants Lead to Channel Over-Activity by Two Different Mechanisms |
Q36938732 | Ethanol interactions with calcium-dependent potassium channels. |
Q37393255 | Ethanol modulates BKCa channels by acting as an adjuvant of calcium |
Q27023757 | Ethanol modulation of mammalian BK channels in excitable tissues: molecular targets and their possible contribution to alcohol-induced altered behavior |
Q50933604 | Evidence that two distinct crypt cell types secrete chloride and potassium in human colon. |
Q61807926 | Expression and Activation of BK Channels in Mice Protects Against Ischemia-Reperfusion Injury of Isolated Hearts by Modulating Mitochondrial Function |
Q30462213 | Expression of BK-type calcium-activated potassium channel splice variants during chick cochlear development |
Q30536899 | FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels |
Q30466258 | Function and mechanism of axonal targeting of voltage-sensitive potassium channels |
Q26995779 | Function and regulation of large conductance Ca(2+)-activated K+ channel in vascular smooth muscle cells |
Q27674992 | Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel |
Q36246219 | Gene Expression Profiling in Slow-Type Calf Soleus Muscle of 30 Days Space-Flown Mice |
Q37775988 | Gene therapy as future treatment of erectile dysfunction |
Q36414675 | Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability. |
Q37599395 | Ginsenoside Rg3 enhances large conductance Ca2+-activated potassium channel currents: a role of Tyr360 residue |
Q46054861 | Heterogeneity in function of small artery smooth muscle BKCa: involvement of the beta1-subunit |
Q30495289 | Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient. |
Q37710852 | Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains |
Q28260416 | Hydrogen sulfide increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells |
Q58708151 | Hydrophobic gating in BK channels |
Q37164921 | Identification and characterization of Ca2+-activated K+ channels in granulosa cells of the human ovary |
Q33924387 | Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and CO |
Q45766565 | Identification of potential novel interaction partners of the sodium-activated potassium channels Slick and Slack in mouse brain. |
Q28481066 | Identification of putative potassium channel homologues in pathogenic protozoa |
Q36183121 | Impaired propulsive motility in the distal but not proximal colon of BK channel β1-subunit knockout mice |
Q55285156 | Incubation of human sperm with micelles made from glycerophospholipid mixtures increases sperm motility and resistance to oxidative stress. |
Q46079125 | Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning |
Q35086508 | Inhibition of Ca2+-activated large-conductance K+ channel activity alters synaptic AMPA receptor phenotype in mouse cerebellar stellate cells |
Q79790423 | Integration of an electric-metal sensory experience in the Slo1 BK channel |
Q41595406 | Integrative Approach for Computationally Inferring Interactions between the Alpha and Beta Subunits of the Calcium-Activated Potassium Channel (BK): a Docking Study |
Q36125024 | Interaction of the BKCa channel gating ring with dendrotoxins |
Q28475707 | Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function |
Q34109981 | Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression |
Q33973304 | Interleukin-4 activates large-conductance, calcium-activated potassium (BKCa) channels in human airway smooth muscle cells |
Q37358094 | Intersubunit coupling in the pore of BK channels |
Q35589894 | Involvement of large-conductance Ca2+-activated K+ channels in chloroquine-induced force alterations in pre-contracted airway smooth muscle |
Q34782668 | Ion channels and drug transporters as targets for anthelmintics |
Q37501925 | Ion channels and receptor as targets for the control of parasitic nematodes |
Q37799103 | Ion channels and their molecular environments – Glimpses and insights from functional proteomics |
Q33888953 | Ion channels, phosphorylation and mammalian sperm capacitation |
Q38110757 | K(+) channels: function-structural overview. |
Q37162392 | K+ channel modulators for the treatment of neurological disorders and autoimmune diseases |
Q41791327 | Keeping you healthy: BK channel activation by omega-3 fatty acids |
Q24338141 | LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium |
Q35349938 | Large conductance Ca2+ -activated K+ channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle |
Q58744394 | Large conductance voltage- and calcium-gated potassium channels (BK) in cerebral artery myocytes of perinatal fetal primates share several major characteristics with the adult phenotype |
Q34475162 | Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling |
Q36059310 | Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol. |
Q46026913 | Large-conductance calcium-activated potassium channels in purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. |
Q35674540 | M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity. |
Q37199211 | Martentoxin, a large-conductance Ca(2+)-activated K(+) channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells |
Q46226383 | Mechanism of C-type natriuretic peptide-induced endothelial cell hyperpolarization |
Q36712653 | Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA. |
Q38738066 | Mesenchymal stem cell-based gene therapy for erectile dysfunction |
Q35063533 | Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus. |
Q37310335 | Methamphetamine Regulation of Firing Activity of Dopamine Neurons |
Q36156951 | Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channels |
Q36426316 | Mitochondria as a drug target in ischemic heart disease and cardiomyopathy |
Q36299702 | Modes of operation of the BKCa channel beta2 subunit |
Q37032053 | Modulation of BK Channel Function by Auxiliary Beta and Gamma Subunits |
Q37025132 | Modulation of BK channel by MicroRNA-9 in neurons after exposure to HIV and methamphetamine |
Q37386448 | Modulation of BKCa channel gating by endogenous signaling molecules |
Q41684514 | Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK Channels |
Q33560844 | Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain |
Q50503225 | Molecular assembly and dynamics of fluorescent protein-tagged single KCa1.1 channel in expression system and vascular smooth muscle cells. |
Q38130386 | Molecular basis of potassium channels in pancreatic duct epithelial cells |
Q48262774 | Molecular determinants of Ca2+ sensitivity at the intersubunit interface of the BK channel gating ring |
Q35807499 | Molecular mechanism of pharmacological activation of BK channels. |
Q35484671 | Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels |
Q37223668 | Molecular mechanisms of BK channel activation |
Q21285088 | Molecular mechanisms of large-conductance ca (2+) -activated potassium channel activation by ginseng gintonin |
Q37269884 | Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channels |
Q34250479 | Movements of individual BKCa channels in live cell membrane monitored by site-specific labeling using quantum dots |
Q90028155 | Multifractal Properties of BK Channel Currents in Human Glioblastoma Cells |
Q36016953 | Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+- and voltage-gated K+ (BK) channels |
Q42452591 | NAD+ activates KNa channels in dorsal root ganglion neurons. |
Q34125126 | NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions. |
Q37081626 | Na+-mediated coupling between AMPA receptors and KNa channels shapes synaptic transmission |
Q33786915 | Neuronal Ca2+-activated K+ channels limit brain infarction and promote survival |
Q33969192 | Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling. |
Q35287498 | On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. |
Q24605639 | Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel |
Q33732977 | Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel |
Q42716027 | Orchestration of stepwise synaptic growth by K+ and Ca2+ channels in Drosophila |
Q38834072 | Over-expression of miR-31 or loss of KCNMA1 leads to increased cisplatin resistance in ovarian cancer cells. |
Q26796569 | Oxidative Stress and Maxi Calcium-Activated Potassium (BK) Channels |
Q58545895 | Oxytocin can regulate myometrial smooth muscle excitability by inhibiting the Na activated K channel, Slo2.1 |
Q41866674 | P2Y1 receptor modulation of Ca2+-activated K+ currents in medium-sized neurons from neonatal rat striatal slices |
Q39643644 | PIP2 PIP2 hooray for maxi K+. |
Q35239318 | Patch clamp and perfusion techniques for studying ion channels expressed in Xenopus oocytes |
Q38198169 | Patch-clamp fluorometry: electrophysiology meets fluorescence. |
Q26771356 | Peptide toxins and small-molecule blockers of BK channels |
Q33911315 | Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition |
Q42015269 | Phosphorylation of BK channels modulates the sensitivity to hydrogen sulfide (H2S). |
Q24646484 | Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol |
Q38062581 | Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives |
Q37362041 | Potassium channels in peripheral pain pathways: expression, function and therapeutic potential |
Q35995334 | Pre- and post-synaptic mechanisms of synaptic strength homeostasis revealed by slowpoke and shaker K+ channel mutations in Drosophila |
Q37276217 | Pregnancy modifies the large conductance Ca2+-activated K+ channel and cGMP-dependent signaling pathway in uterine vascular smooth muscle |
Q37681641 | Premammalian origin of the sperm-specific Slo3 channel. |
Q42490346 | Presynaptic BK channels control transmitter release: physiological relevance and potential therapeutic implications. |
Q36959240 | Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity |
Q33573030 | Properties and physiological function of Ca2+-dependent K+ currents in uniglomerular olfactory projection neurons |
Q47689959 | Protein kinase A-induced internalization of Slack channels from the neuronal membrane occurs by adaptor protein-2/clathrin-mediated endocytosis |
Q37770040 | Regulation and function of potassium channels in aldosterone-sensitive distal nephron |
Q38264119 | Regulation of BK channels by auxiliary γ subunits |
Q33415030 | Regulation of bestrophins by Ca2+: a theoretical and experimental study |
Q38111276 | Regulation of ion channels by membrane lipids |
Q26827261 | Regulation of ion channels by pyridine nucleotides |
Q39031693 | Regulation of large conductance calcium- and voltage-activated potassium (BK) channels by S-palmitoylation |
Q37234574 | Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase |
Q80018720 | Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands |
Q37288568 | Regulation of potassium (K) handling in the renal collecting duct |
Q37251548 | Regulation of synaptic transmission by presynaptic CaMKII and BK channels |
Q33655515 | Regulation of the cGMP-cPKG pathway and large-conductance Ca2+-activated K+ channels in uterine arteries during the ovine ovarian cycle |
Q89287470 | Regulatory Effect of General Anesthetics on Activity of Potassium Channels |
Q34368477 | Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BKCa channel |
Q36130322 | Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing. |
Q34431654 | Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule |
Q31086046 | Role of KCNMA1 in breast cancer |
Q37672153 | Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol |
Q40016769 | Role of spike-frequency adaptation in shaping neuronal response to dynamic stimuli |
Q38241535 | S-acylation dependent post-translational cross-talk regulates large conductance calcium- and voltage- activated potassium (BK) channels |
Q38574185 | S0, where is it? |
Q27310064 | SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification |
Q57132107 | SLO potassium channels antagonize premature decision making in |
Q36982467 | SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics |
Q27312012 | SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants |
Q34092459 | SLO-2 is cytoprotective and contributes to mitochondrial potassium transport |
Q34339412 | SLO-2 potassium channel is an important regulator of neurotransmitter release in Caenorhabditis elegans |
Q36754995 | SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K+ Channels |
Q30500560 | Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans |
Q41168552 | Single-Molecule Imaging of Nav1.6 on the Surface of Hippocampal Neurons Reveals Somatic Nanoclusters |
Q37212425 | Slo1 is the principal potassium channel of human spermatozoa |
Q64116363 | Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice |
Q33347990 | Species-specific Differences among KCNMB3 BK beta3 auxiliary subunits: some beta3 N-terminal variants may be primate-specific subunits |
Q34439620 | Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions |
Q35998331 | Stem Cell Therapy for Diabetic Erectile Dysfunction in Rats: A Meta-Analysis |
Q42363326 | Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. |
Q40093295 | Stimulatory actions of di-8-butyl-amino-naphthyl-ethylene-pyridinium-propyl-sulfonate (di-8-ANEPPS), voltage-sensitive dye, on the BKCa channel in pituitary tumor (GH3) cells |
Q48960168 | Stochastic calcium mechanisms cause dendritic calcium spike variability |
Q35471466 | Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain |
Q33498356 | Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy |
Q24595712 | Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution |
Q36678098 | Subunit-specific effect of the voltage sensor domain on Ca2+ sensitivity of BK channels. |
Q33708230 | Synaptic excitation is regulated by the postsynaptic dSK channel at the Drosophila larval NMJ. |
Q27010580 | Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide |
Q37933435 | Targeting BK (big potassium) channels in epilepsy |
Q28570038 | The BK channel accessory beta1 subunit determines alcohol-induced cerebrovascular constriction |
Q38045185 | The BK channel: a vital link between cellular calcium and electrical signaling. |
Q37665001 | The Ca2+-activated K+ current of human sperm is mediated by Slo3. |
Q30486735 | The Concise Guide to PHARMACOLOGY 2013/14: ion channels |
Q35799328 | The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits. |
Q89619723 | The Epilepsy of Infancy With Migrating Focal Seizures: Identification of de novo Mutations of the KCNT2 Gene That Exert Inhibitory Effects on the Corresponding Heteromeric KNa1.1/KNa1.2 Potassium Channel |
Q35647406 | The LRRC26 protein selectively alters the efficacy of BK channel activators |
Q34028265 | The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements |
Q24657358 | The RCK2 domain of the human BKCa channel is a calcium sensor |
Q41025548 | The RCK2 domain uses a coordination site present in Kir channels to confer sodium sensitivity to Slo2.2 channels |
Q30494642 | The SLO3 sperm-specific potassium channel plays a vital role in male fertility |
Q28588911 | The beta1 subunit of Na+/K+-ATPase interacts with BKCa channels and affects their steady-state expression on the cell surface |
Q42049846 | The calcium-activated slow AHP: cutting through the Gordian knot. |
Q36933248 | The cellular building blocks of breathing |
Q36052381 | The contribution of RCK domains to human BK channel allosteric activation |
Q21129265 | The emerging chondrocyte channelome |
Q47970102 | The role of Ca2+ -dependent K+ - channels at the rat corticostriatal synapses revealed by paired pulse stimulation |
Q46071470 | The role of the large-conductance calcium-dependent potassium channel, BK/Slowpoke, in shaping motor neuron firing during rhythmic activity |
Q28566365 | The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunit |
Q30155988 | The β Subunit of Voltage-Gated Ca2+Channels |
Q36127724 | Transcriptome-based identification of antioxidative gene expression after fish oil supplementation in normo- and dyslipidemic men. |
Q37091597 | Transduction of voltage and Ca2+ signals by Slo1 BK channels |
Q52817063 | Transient BK outward current enhances motoneurone firing rates during Drosophila larval locomotion. |
Q38646018 | Transmembrane allosteric energetics characterization for strong coupling between proton and potassium ion binding in the KcsA channel. |
Q44932684 | Transplantation KCNMA1 modified bone marrow-mesenchymal stem cell therapy for diabetes mellitus-induced erectile dysfunction |
Q47426478 | Tuning the mechanosensitivity of a BK channel by changing the linker length |
Q35234554 | Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels. |
Q37178939 | Two distinct mechanisms of transport through the plasmodial surface anion channel |
Q34073523 | Two distinct pools of large-conductance calcium-activated potassium channels in the somatic plasma membrane of central principal neurons |
Q43073034 | Two slow calcium-activated afterhyperpolarization currents control burst firing dynamics in gonadotropin-releasing hormone neurons. |
Q41520570 | Tyrphostin AG556 increases the activity of large conductance Ca2+ -activated K+ channels by inhibiting epidermal growth factor receptor tyrosine kinase |
Q89763679 | Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors |
Q36969112 | Vascular large conductance calcium-activated potassium channels: functional role and therapeutic potential |
Q39903485 | Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells |
Q38005942 | Worms take to the slo lane: a perspective on the mode of action of emodepside |
Q33673693 | Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain. |
Q30496684 | α-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells |
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