Inhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors

scientific article published on November 1993

Inhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1993PNAS...9010494Y
P356DOI10.1073/PNAS.90.22.10494
P932PMC publication ID47803
P698PubMed publication ID7504266
P5875ResearchGate publication ID15695369

P2093author name stringSteinman L
McDevitt HO
Yang XD
Karin N
Tisch R
P2860cites workVLA proteins in the integrin family: structures, functions, and their role on leukocytesQ37925528
Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.Q37925551
Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigensQ39510598
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.Q41743693
Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alphaQ42813536
Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor-IgG chimaeraQ43581510
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.Q46007698
In vitro analysis of the homing properties of human lymphocytes: developmental regulation of functional receptors for high endothelial venulesQ49255176
Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat.Q52097731
Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophagesQ59052176
Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesionQ67701303
T lymphocyte migration to arthritic joints and dermal inflammation in the rat: differing migration patterns and the involvement of VLA-4Q68033779
Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) miceQ68889645
Antigen-independent processes in antigen-specific immunity. A role for alpha 4 integrinQ70560311
Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single geneQ24307858
Adhesion receptors of the immune systemQ29616393
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversityQ29617967
Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetesQ33474458
A cell-surface molecule involved in organ-specific homing of lymphocytesQ34272163
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylaseQ34566310
Antigen presenting cells and the immunogenetics of autoimmune diabetes in NOD miceQ35195491
Mechanisms of lymphocyte homingQ35453660
Selectins: interpreters of cell-specific carbohydrate information during inflammationQ35532358
Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD proteinQ36231170
Lymphocyte interactions with endothelial cellsQ36286240
Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.Q36353954
Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venulesQ36359810
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchymaQ36361169
Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene productsQ36762461
Vascular cell adhesion molecule 1 induces T-cell antigen receptor-dependent activation of CD4+T lymphocytesQ37553147
Two integrin-binding peptides abrogate T cell-mediated immune responses in vivoQ37593872
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock proteinQ37701871
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectinsulitisQ922215
preventionQ1717246
P304page(s)10494-10498
P577publication date1993-11-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors
P478volume90