| scholarly article | Q13442814 |
| P2093 | author name string | J. F. Costello | |
| B. W. Futscher | |||
| R. O. Pieper | |||
| R. A. Kroes | |||
| P2860 | cites work | Cancer Research | Q326097 |
| Cytosine methylation does not affect binding of transcription factor Sp1 | Q33562281 | ||
| The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia | Q33636876 | ||
| Genomic sequencing and methylation analysis by ligation mediated PCR. | Q34550393 | ||
| Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene | Q35792879 | ||
| High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes: correlation with binding sites for transcription factors | Q36647022 | ||
| Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting | Q36682226 | ||
| Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor | Q36758701 | ||
| Expression of the human ADH2 gene: an unusual Sp1-binding site in the promoter of a gene expressed at high levels in liver | Q38324427 | ||
| High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. | Q38339731 | ||
| CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation | Q38344762 | ||
| Nucleosome structure | Q40289266 | ||
| Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells | Q41460436 | ||
| Epigenetic silencing of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in Mex- human cells | Q41601050 | ||
| Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts | Q41647440 | ||
| Variation in the loss of O6-methylguanine-DNA methyltransferase during immortalization of human fibroblasts | Q41753462 | ||
| DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone | Q42206697 | ||
| Specific protection of methylated CpGs in mammalian nuclei | Q45193660 | ||
| DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1 | Q45715501 | ||
| In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. | Q46545220 | ||
| O6-methylguanine-DNA methyltransferase in human normal and tumor tissue from brain, lung, and ovary | Q48672550 | ||
| Successful chemotherapy for newly diagnosed aggressive oligodendroglioma | Q48983753 | ||
| Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation | Q54274003 | ||
| Alternative chromatin structure at CpG islands | Q57259142 | ||
| Correlation between DNA methylation and expression of O6-methylguanine-DNA methyltransferase gene in cultured human tumor cells | Q67532821 | ||
| Direct Correlation Between Methylation Status and Expression of the Human O-6-MethyIguanine DNA Methyltransferase Gene | Q67699567 | ||
| A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells | Q67920815 | ||
| Inhibition of a specific DNA repair system and nitrosourea cytotoxicity in resistant human cancer cells | Q69319935 | ||
| Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibition | Q69811351 | ||
| Organization and expression of the human gene for O6-methylguanine-DNA methyltransferase | Q72067168 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neoplastic gene expression regulation | Q66660300 |
| P304 | page(s) | 6515-6521 | |
| P577 | publication date | 1994-10-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Methylation-related chromatin structure is associated with exclusion of transcription factors from and suppressed expression of the O-6-methylguanine DNA methyltransferase gene in human glioma cell lines | |
| Methylation-Related Chromatin Structure Is Associated with Exclusion of Transcription Factors from and Suppressed Expression of the O-6-Methylguanine DNA Methyltransferase Gene in Human Glioma Cell Lines | |||
| P478 | volume | 14 |
| Q39599186 | A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts. |
| Q36573030 | Aberrant Silencing of the CpG Island-Containing Human O6-Methylguanine DNA Methyltransferase Gene Is Associated with the Loss of Nucleosome-Like Positioning |
| Q43844093 | Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer |
| Q44838633 | Aberrant methylation of genes in low-grade astrocytomas |
| Q56418625 | Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia |
| Q90102657 | Analysis on the Meiosis-Related Gene (Dmc1, Ph1) Expression in Autotriploid Carassius auratus |
| Q55456723 | Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial. |
| Q37522376 | BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53. |
| Q35855352 | Canadian recommendations for the treatment of glioblastoma multiforme. |
| Q39728639 | Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts |
| Q34606797 | DNA Methylation Analysis of Allotetraploid Hybrids of Red Crucian Carp (Carassius auratus red var.) and Common Carp (Cyprinus carpio L.) |
| Q36069167 | DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors |
| Q36801269 | Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q. |
| Q92893194 | Development and validation of an allele-specific PCR assay for genotyping a promoter and exonic single nucleotide polymorphisms of MGMT gene |
| Q41200333 | Dominant genetic instability and sensitivity to DNA damaging agents in a mammalian cell line |
| Q36866006 | Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models |
| Q37797704 | Epigenetic Drivers of Genetic Alterations |
| Q36226129 | Epigenetic silencing of the MGMT gene in cancer. |
| Q37467299 | Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model |
| Q35787908 | Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment |
| Q90440161 | Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma |
| Q31019127 | Gene MGMT and oligodendrogliomas. Fundamental data and short review of the literature |
| Q37344947 | Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas |
| Q48617766 | In vitro activation of the mouse mid-sized neurofilament gene by an NF-1-like transcription factor |
| Q39908793 | Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells |
| Q36854908 | Intratumoral Heterogeneity of the Epigenome. |
| Q87676566 | MGMT DNA repair gene promoter/enhancer haplotypes alter transcription factor binding and gene expression |
| Q34525704 | MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response |
| Q38218848 | MGMT testing--the challenges for biomarker-based glioma treatment |
| Q28364163 | Methylation matters |
| Q42632071 | Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene |
| Q40023435 | Methylation of Discrete Regions of the O6-Methylguanine DNA Methyltransferase (MGMT) CpG Island Is Associated with Heterochromatinization of the MGMT Transcription Start Site and Silencing of the Gene |
| Q33887440 | Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression |
| Q38289376 | Methylation-associated Transcriptional Silencing of the Major Histocompatibility Complex-linked hsp70 Genes in Mouse Cell Lines |
| Q38692922 | MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT. |
| Q37533620 | Molecular epigenetics and genetics in neuro-oncology |
| Q24685624 | O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions |
| Q89497366 | O6-Methylguanine-DNA Methyltransferase (MGMT): Challenges and New Opportunities in Glioma Chemotherapy |
| Q37899984 | O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry |
| Q26853112 | O6-Methylguanine-DNA methyltransferase in glioma therapy: Promise and problems |
| Q37729676 | Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge |
| Q44532454 | Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O(6) -methylguanine DNA methyltransferase expression |
| Q39716063 | Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells |
| Q34478948 | Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review). |
| Q38309365 | Regulation of the human O(6)-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300. |
| Q48256976 | Repair gene O6 -methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation. |
| Q41027968 | Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus |
| Q37580498 | Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype |
| Q33771160 | Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma |
| Q34280188 | Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer |
| Q73308150 | Structure and function analysis of the human myeloid cell nuclear differentiation antigen promoter: evidence for the role of Sp1 and not of c-Myb or PU.1 in myelomonocytic lineage-specific expression |
| Q29615066 | Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer |
| Q34418243 | The imprinted gene LRRTM1 mediates schizotypy and handedness in a nonclinical population |
| Q48891682 | The promoter hypermethylation status of GATA6, MGMT, and FHIT in glioblastoma |
| Q30475852 | Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter |
| Q28273012 | Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents |
| Q30428760 | Understanding and manipulating O6-methylguanine-DNA methyltransferase expression |
| Q37580383 | miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely |
| Q42925815 | p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor |
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