| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Erik De Clercq | Q13578863 |
| P2093 | author name string | Irene M Lagoja | |
| P2860 | cites work | Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6 | Q22010648 |
| Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin | Q24680353 | ||
| Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization | Q27658909 | ||
| Structures of aromatic inhibitors of influenza virus neuraminidase | Q27730394 | ||
| Anti-influenza virus activity of peramivir in mice with single intramuscular injection | Q28284987 | ||
| Influenza: old and new threats | Q28296381 | ||
| Evaluation of the anti-influenza virus activities of 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and its sodium salt | Q28328612 | ||
| Novel alpha- and beta-amino acid inhibitors of influenza virus neuraminidase | Q28345965 | ||
| Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities | Q28349496 | ||
| Comparison of the anti-influenza virus activity of RWJ-270201 with those of oseltamivir and zanamivir | Q28360732 | ||
| Hydrophobic benzoic acids as inhibitors of influenza neuraminidase | Q28368172 | ||
| Synthesis and evaluation of 1,4,5,6-tetrahydropyridazine derivatives as influenza neuraminidase inhibitors | Q28369233 | ||
| In vitro and in vivo anti-influenza A virus activity of antisense oligonucleotides | Q28372196 | ||
| Synthesis of 2-(2-adamantyl)piperidines and structure anti-influenza virus A activity relationship study using a combination of NMR spectroscopy and molecular modeling | Q28378245 | ||
| A novel antiviral agent which inhibits the endonuclease of influenza viruses | Q28378972 | ||
| Anti-influenza virus activities of 4-substituted 2,4-dioxobutanoic acid inhibitors | Q28378984 | ||
| Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection. | Q30307313 | ||
| Therapeutic options for the management of influenza | Q30308458 | ||
| Role of hemagglutinin cleavage for the pathogenicity of influenza virus. | Q30322358 | ||
| Prophylaxis and treatment of influenza virus infection. | Q30328367 | ||
| The role of antivirals in the control of influenza. | Q30332718 | ||
| A novel mechanism for the acquisition of virulence by a human influenza A virus | Q30431264 | ||
| Oral LY217896 for prevention of experimental influenza A virus infection and illness in humans | Q30451269 | ||
| Oral ribavirin treatment of influenza A and B. | Q30451750 | ||
| Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivity | Q30452569 | ||
| In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication | Q30453074 | ||
| Salicylamide inhibitors of influenza virus fusion | Q31426813 | ||
| BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design | Q31440495 | ||
| Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus | Q31943359 | ||
| Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin | Q31957799 | ||
| Neuraminidase inhibitors as anti-influenza virus agents | Q33730159 | ||
| Approaches and strategies for the treatment of influenza virus infections | Q33730165 | ||
| New, azide-free transformation of epoxides into 1,2-diamino compounds: synthesis of the anti-influenza neuraminidase inhibitor oseltamivir phosphate (Tamiflu). | Q33942318 | ||
| Highlights in the development of new antiviral agents | Q33961840 | ||
| Antimicrobial peptides and proteins in the innate defense of the airway surface | Q34129369 | ||
| Triflimide activation of a chiral oxazaborolidine leads to a more general catalytic system for enantioselective Diels-Alder addition. | Q34202783 | ||
| Anti-influenza drugs and neuraminidase inhibitors | Q34288105 | ||
| The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor | Q34331495 | ||
| Targets of anti-influenza chemotherapy other than neuraminidase and proton pump. | Q34397518 | ||
| Neuraminidase inhibitors for influenza | Q34455162 | ||
| Enantioselective synthesis of antiinfluenza compound A-315675. | Q43435444 | ||
| Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides | Q43552108 | ||
| Synthesis of 2-substituted (+/-)-(2r,3r,5r)-tetrahydrofuran-3,5-dicarboxylic acid derivatives | Q43574185 | ||
| Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores | Q43582414 | ||
| Synthesis of a carbocyclic sialic acid analogue for the inhibition of influenza virus neuraminidase | Q43637484 | ||
| Novel 3-(2-adamantyl)pyrrolidines with potent activity against influenza A virus-identification of aminoadamantane derivatives bearing two pharmacophoric amine groups | Q43713806 | ||
| An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology | Q43723308 | ||
| Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity | Q43812035 | ||
| Total synthesis of A-315675: a potent inhibitor of influenza neuraminidase | Q43969070 | ||
| A new synthesis of Neu5Ac from D-glucono-delta-lactone | Q44134848 | ||
| Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine | Q44207143 | ||
| Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir | Q44363638 | ||
| Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents. | Q44466643 | ||
| Basis for the potent inhibition of influenza virus infection by equine and guinea pig alpha 2-macroglobulin | Q44513817 | ||
| Action of epsilon-aminocaproic acid on the proteolysis system during experimental influenza in mice | Q44526413 | ||
| N-Acetyl-6-sulfo-d-glucosamine as a promising mimic of N-Acetyl neuraminic acid | Q44651570 | ||
| Synthesis of a new stable conformationally constrained 2,7-anhydrosialic acid derivative | Q44662993 | ||
| Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase | Q44790091 | ||
| Syntheses and neuraminidase inhibitory activity of multisubstituted cyclopentane amide derivatives | Q44823640 | ||
| Novel assay for the influenza virus M2 channel activity | Q44963422 | ||
| Ligand recognition by influenza virus. The binding of bivalent sialosides | Q44975303 | ||
| A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection | Q45148150 | ||
| ANTIVIRAL ACTIVITY OF 1-ADAMANTANAMINE (AMANTADINE). | Q45153220 | ||
| Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. | Q45176017 | ||
| Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents | Q45423733 | ||
| Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo | Q45461388 | ||
| In vitro anti-influenza virus activity of the pavine alkaloid (-)-thalimonine isolated from Thalictrum simplex L. | Q45722645 | ||
| Aromatic sialic acid analogues as potential inhibitors of influenza virus neuraminidase | Q45736784 | ||
| Metal ion catalysis of RNA cleavage by the influenza virus endonuclease | Q45749822 | ||
| Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entry | Q45780778 | ||
| Effect of the virostatic Norakin (triperiden) on influenza virus activities | Q45782616 | ||
| Mode of action of the anti-influenza virus activity of plant flavonoid, 5,7,4'-trihydroxy-8-methoxyflavone, from the roots of Scutellaria baicalensis | Q45785908 | ||
| Effective inhibitors of hemagglutination by influenza virus synthesized from polymers having active ester groups. Insight into mechanism of inhibition | Q45790757 | ||
| Prevention and treatment of experimental influenza A virus infection in volunteers with a new antiviral ICI 130,685. | Q45830928 | ||
| Inhibition of influenza virus sialidase and anti-influenza virus activity by plant flavonoids | Q45848829 | ||
| Inhibition of influenza virus A/WSN replication by a trypsin inhibitor, 6-amidino-2-naphthyl p-guanidinobenzoate | Q45849169 | ||
| The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus. | Q46409785 | ||
| Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors | Q46534489 | ||
| Heterocyclic rimantadine analogues with antiviral activity | Q46913379 | ||
| Synthesis of 2'-(4-methylumbelliferyl)-.alpha.-D-N-acetylneuraminic acid and detection of skin fibroblast neuraminidase in normal humans and in sialidosis | Q46954495 | ||
| Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A. | Q50587585 | ||
| Antiviral agents in influenza--summary of Influenza Workshop VIII. | Q50592921 | ||
| The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu ® ): A Challenge for Synthesis & Process Research | Q56031755 | ||
| Inhibitory effect of a protease inhibitor, leupeptin, on the development of influenza pneumonia, mediated by concomitant bacteria | Q68163009 | ||
| Monomeric inhibitors of influenza neuraminidase enhance the hemagglutination inhibition activities of polyacrylamides presenting multiple C-sialoside groups | Q71533642 | ||
| Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity | Q73086162 | ||
| Synthesis of 6-acetamido-5-amino- and -5-guanidino-3, 4-dehydro-N-(2-ethylbutyryl)- 3-piperidinecarboxylic acids related to zanamivir and oseltamivir, inhibitors of influenza virus neuraminidases | Q73255922 | ||
| Synthesis of the sialidase inhibitor siastatin B | Q73287599 | ||
| Sialidase inhibitors related to zanamivir: synthesis and biological evaluation of 4H-pyran 6-ether and ketone | Q74658143 | ||
| Synthesis of oligomers derived from amide-linked neuraminic acid analogues | Q76315331 | ||
| The human mucus protease inhibitor and its mutants are novel defensive compounds against infection with influenza A and Sendai viruses | Q77917009 | ||
| Synthesis of an influenza neuraminidase inhibitor intermediate via a highly diastereoselective coupling reaction | Q78007572 | ||
| Synthesis of 4-azido-4-deoxy-Neu5,7,8,9Ac42en1Me. A key intermediate for the synthesis of GG167 from D-glucono-delta-lactone | Q80207343 | ||
| Molecule of the month: oseltamivir phosphate (Tamiflu) | Q82617040 | ||
| Oseltamivir becomes plentiful--but still not cheap | Q83181499 | ||
| Transition Metal Catalyzed Synthesis of Arylamines and Aryl Ethers from Aryl Halides and Triflates: Scope and Mechanism | Q88519399 | ||
| Inhibition of influenza virus production in virus-infected mice by RNA interference | Q34514513 | ||
| Protection against lethal influenza virus challenge by RNA interference in vivo. | Q34514565 | ||
| A short enantioselective pathway for the synthesis of the anti-influenza neuramidase inhibitor oseltamivir from 1,3-butadiene and acrylic acid | Q34523359 | ||
| Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity | Q34565520 | ||
| Natural Product Origins of Hsp90 Inhibitors | Q35551866 | ||
| Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus | Q35863279 | ||
| Antiviral therapy for influenza : a clinical and economic comparative review | Q35876328 | ||
| Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus | Q35884171 | ||
| Recent advances in anti-influenza agents with neuraminidase as target | Q36448796 | ||
| Polyacrylamides bearing pendant alpha-sialoside groups strongly inhibit agglutination of erythrocytes by influenza A virus: multivalency and steric stabilization of particulate biological systems | Q36724102 | ||
| Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin | Q36771495 | ||
| Direct inactivation of viruses by human granulocyte defensins | Q36870809 | ||
| Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells | Q37481771 | ||
| Mechanism of binding of surfactant protein D to influenza A viruses: importance of binding to haemagglutinin to antiviral activity. | Q38307755 | ||
| Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid | Q38462263 | ||
| Antiviral therapy with small particle aerosols | Q39309529 | ||
| Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque | Q39362979 | ||
| Biochemistry and clinical applications of ribavirin | Q39460438 | ||
| The molecular biology of influenza virus pathogenicity | Q39520174 | ||
| In vitro and in vivo activities of anti-influenza virus compound T-705. | Q39651429 | ||
| Oral administration of cyclopentane neuraminidase inhibitors protects ferrets against influenza virus infection | Q39651456 | ||
| Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide | Q39752742 | ||
| Growth impairment resulting from expression of influenza virus M2 protein in Saccharomyces cerevisiae: identification of a novel inhibitor of influenza virus | Q39780577 | ||
| Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine | Q39780754 | ||
| A novel class of potent influenza virus inhibitors: polysubstituted acylthiourea and its fused heterocycle derivatives | Q40363445 | ||
| Influenza viruses, cell enzymes, and pathogenicity | Q40408314 | ||
| Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza. | Q40435698 | ||
| A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-Derived zinc-Chelating trioxa-adamantane-triol | Q40548890 | ||
| A new modified DNA enzyme that targets influenza virus A mRNA inhibits viral infection in cultured cells | Q40585082 | ||
| Spiro[pyrrolidine-2,2'-adamantanes]: synthesis, anti-influenza virus activity and conformational properties | Q40590467 | ||
| Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives | Q40611558 | ||
| Heterocyclic rimantadine analogues with antiviral activity | Q40612283 | ||
| Synthesis of substituted 1-norbornylamines with antiviral activity | Q40678852 | ||
| Mechanism of action of T-705 against influenza virus | Q41091905 | ||
| Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2. | Q41174349 | ||
| Inhibitory effect of bafilomycin A1, a specific inhibitor of vacuolar-type proton pump, on the growth of influenza A and B viruses in MDCK cells | Q41315096 | ||
| Synthesis and antiviral activity evaluation of some aminoadamantane derivatives | Q41443005 | ||
| Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones | Q41565125 | ||
| Resistance of mice to reinfection after E-aminocaproic acid treatment of primary influenza virus infection | Q41900517 | ||
| Mechanism of uncoating of influenza B virus in MDCK cells: action of chloroquine | Q41921414 | ||
| A prospective double-blind study of side effects associated with the administration of amantadine for influenza A virus prophylaxis | Q42271923 | ||
| Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents | Q42289235 | ||
| Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors | Q42541298 | ||
| Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides | Q42543989 | ||
| Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design | Q42545974 | ||
| THE IN VIVO ANTIVIRAL ACTIVITY OF 1-ADAMANTANAMINE (AMANTADINE). I. PROPHYLACTIC AND THERAPEUTIC ACTIVITY AGAINST INFLUENZA VIRUSES. | Q43210715 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 1-38 | |
| P577 | publication date | 2008-01-01 | |
| P1433 | published in | Medicinal Research Reviews | Q2436033 |
| P1476 | title | Anti-influenza virus agents: synthesis and mode of action | |
| P478 | volume | 28 |
| Q39816982 | (1-Adamant-yl)(3-amino-phen-yl)methanone |
| Q26771734 | An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014 |
| Q38790676 | Application of virus-like particles (VLP) to NMR characterization of viral membrane protein interactions |
| Q34344583 | Characterization of influenza hemagglutinin interactions with receptor by NMR. |
| Q56786318 | ChemInform Abstract: Antiinfluenza Virus Agents: Synthesis and Mode of Action |
| Q39776237 | Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus |
| Q34253013 | Discovery and SAR study of piperidine-based derivatives as novel influenza virus inhibitors |
| Q30427556 | Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus |
| Q33452730 | Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus |
| Q56786308 | Emerging antiviral drugs |
| Q37428264 | Evidence for a novel gene associated with human influenza A viruses |
| Q41781195 | Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus |
| Q38452544 | Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus |
| Q30369353 | Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel. |
| Q34979296 | Glycyrrhizin inhibits influenza A virus uptake into the cell |
| Q34341508 | In Vitro inhibitory activity of Alpinia katsumadai extracts against influenza virus infection and hemagglutination |
| Q30151464 | Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway |
| Q37450711 | Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides |
| Q28534616 | Inhibition of influenza H7 hemagglutinin-mediated entry |
| Q43288824 | Looking back in 2009 at the dawning of antiviral therapy now 50 years ago an historical perspective |
| Q57376798 | Macromolecular (pro)drugs in antiviral research |
| Q42177559 | Mechanisms of action and efficacy of statins against influenza. |
| Q41763032 | Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. |
| Q30363789 | Mutagenesis studies of the H5 influenza hemagglutinin stem loop region. |
| Q34075986 | Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry. |
| Q30419301 | Recent advances in neuraminidase inhibitor development as anti-influenza drugs |
| Q27675846 | Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus |
| Q33866738 | Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors |
| Q38796348 | Targeting the Channel Activity of Viroporins. |
| Q37618653 | The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures |
Search more.