Dendritic cells and vaccine design for sexually-transmitted diseases

scientific article published on 29 November 2012

Dendritic cells and vaccine design for sexually-transmitted diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.MICPATH.2012.11.010
P932PMC publication ID3596496
P698PubMed publication ID23201532
P5875ResearchGate publication ID233827847

P50authorGerard ZurawskiQ59699408
P2093author name stringLing Ni
Sangkon Oh
Katherine Upchurch
Hyemee Joo
Dorothee Duluc
Michael Carley
Muriel Boreham
Jack Stecher
Julien Gannevat
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Langerhans cells cross-present antigen derived from skinQ34650867
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Evaluation of a broadly protective Chlamydia-cholera combination vaccine candidateQ34883543
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cellsQ34887778
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Dendritic cell control of tolerogenic responsesQ34982085
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New concepts in immunity to Neisseria gonorrhoeae: innate responses and suppression of adaptive immunity favor the pathogen, not the hostQ35155273
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Dendritic cells in immunity and tolerance-do they display opposite functions?Q35181775
Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responsesQ35184456
Comparison of the oral, rectal, and vaginal immunization routes for induction of antibodies in rectal and genital tract secretions of womenQ35545581
High-risk human papilloma virus infection decreases the frequency of dendritic Langerhans' cells in the human female genital tractQ45420696
Immune responses and protection against vaginal infection after nasal or vaginal immunization with attenuated herpes simplex virus type-2.Q45745771
The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b moleculesQ46385893
Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent responseQ47757156
Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responsesQ47862092
Endometrial epithelial cell responses to coinfecting viral and bacterial pathogens in the genital tract can activate the HIV-1 LTR in an NF{kappa}B-and AP-1-dependent manner.Q51450449
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody.Q51475003
Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation.Q51765801
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Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.Q53085484
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Antigen crosspresentation by human plasmacytoid dendritic cells.Q55044627
Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cellsQ57134111
Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL PrimingQ57227729
The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cellsQ57275938
Toll-dependent selection of microbial antigens for presentation by dendritic cellsQ59063722
Functional interactions between dendritic cells and NK cells during viral infectionQ60489540
Expression and gene transcript of Fc receptors for IgG, HLA class II antigens and Langerhans cells in human cervico-vaginal epitheliumQ67524599
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Langerhans cells and T lymphocyte subsets in the murine vagina and cervixQ70138414
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Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infectionQ74410125
Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentationQ78298259
Cutting Edge: Plasmacytoid dendritic cells provide innate immune protection against mucosal viral infection in situQ79370164
Preferential induction of CD4+ T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1Q80057988
Antigenic targeting of the human mannose receptor induces tumor immunityQ80257353
Transcutaneous immunization in mice: induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus-induced tumorsQ80955695
Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)Q81235605
Human langerhans cells are more efficient than CD14(-)CD1c(+) dermal dendritic cells at priming naive CD4(+) T cellsQ82671265
Oral toleranceQ83849376
Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cellsQ84569562
Dendritic cells as potential targets for mucosal immunotherapyQ37595311
The multifaceted influence of the mucosal microflora on mucosal dendritic cell responsesQ37600188
The role of the local microenvironment in regulating susceptibility and immune responses to sexually transmitted viruses in the female genital tract.Q37621725
Dendritic cell subsets in primary and secondary T cell responses at body surfacesQ37633373
Tolerogenic plasmacytoid DC.Q37683083
The CD8+ dendritic cell subsetQ37700814
Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.Q37700833
Tolerance and protection against infection in the genital tract.Q37744918
Increased prevalence of sexually transmitted viral infections in women: the role of female sex hormones in regulating susceptibility and immune responses.Q37836133
High-throughput proteomic screening identifies Chlamydia trachomatis antigens that are capable of eliciting T cell and antibody responses that provide protection against vaginal challengeQ37848686
Harnessing dendritic cells for immunotherapyQ37850082
A novel recombinant multisubunit vaccine against ChlamydiaQ37866603
An Inclusion Membrane Protein from Chlamydia trachomatis Enters the MHC Class I Pathway and Stimulates a CD8+ T Cell ResponseQ37868388
DNA immunization with pgp3 gene of Chlamydia trachomatis inhibits the spread of chlamydial infection from the lower to the upper genital tract in C3H/HeN miceQ37870263
Intestinal CD103+ dendritic cells: master regulators of tolerance?Q37911701
Priming of CD8+ and CD4+ T cells in experimental leishmaniasis is initiated by different dendritic cell subtypesQ38920978
A novel Th cell epitope of Candida albicans mediates protection from fungal infectionQ39359695
Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificityQ39621141
Concomitant activation and antigen uptake via human dectin-1 results in potent antigen-specific CD8+ T cell responsesQ39664739
HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.Q39787210
hDectin-1 is involved in uptake and cross-presentation of cellular antigensQ40094275
Human mannose receptor (CD206) in immune response: novel insights into vaccination strategies using a humanized mouse modelQ40179068
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Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA moleculesQ40587048
NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cellsQ40618321
Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signalingQ40748984
Mucosal immunity in the female genital tractQ41682837
The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligandQ42012073
Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cellsQ42012476
Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitroQ42022012
A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodesQ42039464
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cellsQ42767669
Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturationQ42861996
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Immunogenicity and safety of an HIV-1 lipopeptide vaccine in healthy adults: a phase 2 placebo-controlled ANRS trialQ42972328
The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells.Q42995801
Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cellsQ43120646
Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cellsQ43647446
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cellsQ43891685
Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cellsQ43999066
A controlled trial of a human papillomavirus type 16 vaccineQ44366335
The effect of hormonal contraception on genital tract shedding of HIV-1.Q44838458
CD8 alpha- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis.Q44910134
Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humansQ45221904
Identification of B- and T-cell epitopes from glycoprotein B of herpes simplex virus 2 and evaluation of their immunogenicity and protection efficacyQ45362381
The role of dendritic cells in immune responses against vaginal infection by herpes simplex virus type 2Q35586464
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cellsQ35679596
Identifying epitopes of HIV-1 that induce protective antibodiesQ35708836
Chemokine receptors and leukocyte trafficking in the mucosal immune system.Q35794672
Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.Q35830147
Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjectsQ35854117
The interface between innate and adaptive immunityQ35904384
Plasmacytoid dendritic cells in immunityQ35953140
Dendritic cells control B cell growth and differentiationQ35963666
Immunologic uniqueness of the genital tract: challenge for vaccine developmentQ36099546
Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiationQ36118295
Glycoprotein G of herpes simplex virus 2 as a novel vaccine antigen for immunity to genital and neurological diseaseQ36155337
Dendritic cells prime natural killer cells by trans-presenting interleukin 15Q36157184
Cutaneous dendritic cellsQ36161713
Unique features of antiviral immune system of the vaginal mucosaQ36177229
Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunityQ36199422
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responsesQ36228375
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccineQ36228405
Vaginal epithelial dendritic cells renew from bone marrow precursorsQ36277209
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cellsQ36369028
Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2Q36370493
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph nodeQ36371218
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell toleranceQ36376611
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccinationQ36402359
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cellsQ36404025
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and toleranceQ36426325
Functional diversity of human vaginal APC subsets in directing T-cell responsesQ36597690
Dendritic cells: translating innate to adaptive immunity.Q36627111
Myeloid C-type lectins in innate immunityQ36655901
Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.Q36858877
P407language of work or nameEnglishQ1860
P921main subjectvaccine engineeringQ14861085
dendritic cellQ506253
sexually transmitted infectionQ12198
sexual transmissionQ45349134
P304page(s)35-44
P577publication date2012-11-29
P1433published inMicrobial PathogenesisQ15766470
P1476titleDendritic cells and vaccine design for sexually-transmitted diseases
P478volume58

Reverse relations

cites work (P2860)
Q40067153A Herpes Simplex Virus Type 2 Deleted for Glycoprotein D Enables Dendritic Cells to Activate CD4+ and CD8+ T Cells
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Q39538711The HPV16 E7 Oncoprotein Disrupts Dendritic Cell Function and Induces the Systemic Expansion of CD11b(+)Gr1(+) Cells in a Transgenic Mouse Model
Q34721358Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments

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