Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord

scientific article published on April 2013

Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DEV.090845
P8608Fatcat IDrelease_7ounz7aq4baatlj7kvepi5mwze
P932PMC publication ID3596997
P698PubMed publication ID23482494
P5875ResearchGate publication ID236038853

P50authorMichael P MatiseQ86910180
P2093author name stringKwanha Yu
Sean McGlynn
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Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3Q28140330
Sonic hedgehog regulates growth and morphogenesis of the toothQ28141998
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferationQ28211798
A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 geneQ28263330
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene functionQ28291924
Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1Q28296269
Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defectQ28506101
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous systemQ28507070
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationQ28507411
All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3Q28508067
Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviorsQ28512657
The Sox9 transcription factor determines glial fate choice in the developing spinal cordQ28512816
Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cordQ28513190
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cordQ28586729
Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrainQ28587651
Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signalingQ28591338
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant miceQ28594168
FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanismQ28594311
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connectionQ28594759
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathwayQ28634556
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxietyQ29615160
Neuronal specification in the spinal cord: inductive signals and transcriptional codesQ29616039
Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad levelQ33358143
Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehogQ33598663
Developmental genetics of vertebrate glial-cell specification.Q34149150
Identification of a neural stem cell in the adult mammalian central nervous systemQ34492720
Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterningQ34749893
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional networkQ34795340
Glial specification in the vertebrate neural tubeQ35752440
Astrocytes and disease: a neurodevelopmental perspectiveQ35945056
Sonic hedgehog signaling in the developing CNS where it has been and where it is goingQ37954781
Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elementsQ38363013
Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradationQ39739721
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasomeQ40174315
Sonic hedgehog regulates discrete populations of astrocytes in the adult mouse forebrainQ42001198
Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.Q42860229
Expression of S-100 protein is related to neuronal damage in MPTP-treated miceQ44389381
Chronic gliosis induced by loss of S-100B: knockout mice have enhanced GFAP-immunoreactivity but blunted response to a serotonin challengeQ45203185
The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord.Q46164445
Effects on neurite outgrowth and cell survival of a secreted fibroblast growth factor binding protein upregulated during spinal cord injuryQ48078993
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.Q48199490
Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells.Q48409266
Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.Q48460829
Sonic hedgehog controls epaxial muscle determination through Myf5 activation.Q52174934
A Requirement for Retinoic Acid-Mediated Transcriptional Activation in Ventral Neural Patterning and Motor Neuron SpecificationQ63488115
P433issue7
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)1594-1604
P577publication date2013-04-01
P1433published inDevelopmentQ3025404
P1476titleFloor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord
P478volume140

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