| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.VASCN.2006.10.002 |
| P698 | PubMed publication ID | 17174577 |
| P2093 | author name string | Ray Bakhtiar | |
| Tapan K Majumdar | |||
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| Use of online-dual-column extraction in conjunction with chiral liquid chromatography tandem mass spectrometry for determination of terbutaline enantiomers in human plasma | Q33425765 | ||
| Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery | Q33426171 | ||
| Adduct formation in quantitative bioanalysis: effect of ionization conditions on paclitaxel | Q33431416 | ||
| Unexpected observation of ion suppression in a liquid chromatography/atmospheric pressure chemical ionization mass spectrometric bioanalytical method | Q33431699 | ||
| Matrix effect in LC-ESI-MS and LC-APCI-MS with off-line and on-line extraction procedures | Q33432629 | ||
| Sensitivity enhancement in liquid chromatography/atmospheric pressure ionization mass spectrometry using derivatization and mobile phase additives | Q33433393 | ||
| Thermally induced N-to-O rearrangement of tert-N-oxides in atmospheric pressure chemical ionization and atmospheric pressure photoionization mass spectrometry: differentiation of N-oxidation from hydroxylation and potential determination of N-oxidat | Q33433464 | ||
| LC-MS Development strategies for quantitative bioanalysis | Q33435452 | ||
| Characterization of typical chemical background interferences in atmospheric pressure ionization liquid chromatography-mass spectrometry | Q33435968 | ||
| Effect of high-performance liquid chromatography mobile phase components on sensitivity in negative atmospheric pressure chemical ionization liquid chromatography-mass spectrometry | Q33459756 | ||
| The effect of the mobile phase additives on sensitivity in the analysis of peptides and proteins by high-performance liquid chromatography-electrospray mass spectrometry. | Q34561630 | ||
| Practical implications of some recent studies in electrospray ionization fundamentals | Q34629358 | ||
| Chemistry for peptide and protein PEGylation | Q34674747 | ||
| Derivatization of phospholipids | Q35184906 | ||
| A critical evaluation of high performance liquid chromatography-electrospray ionisation-mass spectrometry and capillary electrophoresis-electrospray-mass spectrometry for the detection and determination of small molecules of significance in clinical | Q35799528 | ||
| Column-switching procedures for the fast analysis of drugs in biologic samples | Q35823309 | ||
| Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry | Q36184328 | ||
| Stabilizing drug molecules in biological samples | Q36262931 | ||
| Applications of mass spectrometry in early stages of target based drug discovery | Q36300251 | ||
| Fast mass spectrometry-based methodologies for pharmaceutical analyses | Q36384760 | ||
| Direct analysis of a polar pharmaceutical compound in plasma using ultra-high flow rate liquid chromatography/mass spectrometry with a mixed-mode column | Q43825915 | ||
| Interference of a carbamoyl glucuronide metabolite in quantitative liquid chromatography/tandem mass spectrometry | Q43831406 | ||
| A strategy for a post-method-validation use of incurred biological samples for establishing the acceptability of a liquid chromatography/tandem mass-spectrometric method for quantitation of drugs in biological samples | Q44119611 | ||
| Noncovalent dimerization of paclitaxel in solution: evidence from electrospray ionization mass spectrometry | Q44124478 | ||
| Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry | Q44268458 | ||
| Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS. | Q44305739 | ||
| The importance of chromatographic separation in LC/MS/MS quantitation of drugs in biological fluids: detection, characterization, and synthesis of a previously unknown low-level nitrone metabolite of a substance P antagonist | Q44314197 | ||
| Comparison of peak shapes obtained with volatile (mass spectrometry-compatible) buffers and conventional buffers in reversed-phase high-performance liquid chromatography of bases on particulate and monolithic columns | Q44338768 | ||
| Investigation of EDTA anticoagulant in plasma to improve the throughput of liquid chromatography/tandem mass spectrometric assays | Q44421554 | ||
| Shift in pH of biological fluids during storage and processing: effect on bioanalysis | Q44622478 | ||
| Synthesis and Evaluation of PEG414, a Novel Formulating Agent that Avoids Analytical Problems Associated with Polydisperse Vehicles such as PEG400 | Q44645946 | ||
| A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes | Q44909535 | ||
| Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not? | Q45220803 | ||
| Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine | Q45284742 | ||
| Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds | Q46742665 | ||
| Analysis of omeprazole and 5-OH omeprazole in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry (HILIC-MS/MS)--eliminating evaporation and reconstitution steps in 96-well liquid/liquid extraction | Q46812198 | ||
| A 96-well single-pot protein precipitation, liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of muraglitazar, a novel diabetes drug, in human plasma | Q46876292 | ||
| Sources of artefacts in the electrospray ionization mass spectra of saturated diacylglycerophosphocholines: from condensed phase hydrolysis reactions through to gas phase intercluster reactions | Q46916739 | ||
| High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS). | Q46928125 | ||
| Matrix effects on accurate mass measurements of low-molecular weight compounds using liquid chromatography-electrospray-quadrupole time-of-flight mass spectrometry. | Q46938065 | ||
| Liquid chromatography-mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrix ionization effects in plasma | Q46960240 | ||
| Shortcomings of protein removal prior to high performance liquid chromatographic analysis-A case study using method development for BAY 11-7082. | Q46985397 | ||
| Determination of chlorpyrifos and its metabolites in rat brain tissue using coupled-column liquid chromatography/electrospray ionization tandem mass spectrometry. | Q48446014 | ||
| Optimizing an ultrafast generic high-performance liquid chromatography/tandem mass spectrometry method for faster discovery pharmacokinetic sample throughput. | Q48767750 | ||
| Evaluation of automated single mass spectrometry to tandem mass spectrometry function switching for comprehensive drug profiling analysis using a quadrupole time-of-flight mass spectrometer. | Q49168681 | ||
| Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry. | Q54455855 | ||
| The need for chromatographic and mass resolution in liquid chromatography/tandem mass spectrometric methods used for quantitation of lactones and corresponding hydroxy acids in biological samples | Q73007542 | ||
| Protonation in electrospray mass spectrometry: wrong-way-round or right-way-round? | Q73176713 | ||
| Simultaneous quantification of seven active metabolites of roxifiban in human plasma by LC/MS/MS in the presence of an interfering displacer at millimolar concentrations | Q73234405 | ||
| Effects of mobile-phase additives, solution pH, ionization constant, and analyte concentration on the sensitivities and electrospray ionization mass spectra of nucleoside antiviral agents | Q73331090 | ||
| Characterization of a technique for rapid pharmacokinetic studies of multiple co-eluting compounds by LC/MS/MS | Q73509267 | ||
| Cone voltage induced in-source dissociation of glucuronides in electrospray and implications in biological analyses | Q73559576 | ||
| Higher throughput bioanalysis by automation of a protein precipitation assay using a 96-well format with detection by LC-MS/MS | Q73597435 | ||
| Derivatization for electrospray ionization-mass spectrometry. 4. Alkenes and alkynes | Q73821849 | ||
| A predictive model for matrix and analyte effects in electrospray ionization of singly-charged ionic analytes | Q73958808 | ||
| Quantitative liquid chromatographic-tandem mass spectrometric determination of reserpine in FVB/N mouse plasma using a "chelating" agent (disodium EDTA) for releasing protein-bound analytes during 96-well liquid-liquid extraction | Q74019216 | ||
| Negative ion electrospray high-performance liquid chromatography-mass spectrometry method development for determination of a highly polar phosphonic acid/sulfonic acid compound in plasma. Optimization of ammonium acetate concentration and in-source | Q74111296 | ||
| Derivatization for electrospray ionization mass spectrometry. 3. Electrochemically ionizable derivatives | Q74504195 | ||
| High performance liquid chromatography mobile phase composition optimization for the quantitative determination of a carboxylic acid compound in human plasma by negative ion electrospray high performance liquid chromatography tandem mass spectrometr | Q74543161 | ||
| A study of ion suppression effects in electrospray ionization from mobile phase additives and solid-phase extracts | Q75199195 | ||
| Validated HPLC/MS/MS assay for CI-1011 in rat plasma and a comparison with an HPLC/UV assay | Q77506352 | ||
| The investigation and the use of high flow column-switching LC/MS/MS as a high-throughput approach for direct plasma sample analysis of single and multiple components in pharmacokinetic studies | Q77616743 | ||
| The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds | Q78004126 | ||
| Application of co-eluting structural analog internal standards for expanded linear dynamic range in liquid chromatography/electrospray mass spectrometry | Q78827990 | ||
| Monolithic materials: Promises, challenges, achievements | Q79769792 | ||
| Identification and reduction of ion suppression effects on pharmacokinetic parameters by polyethylene glycol 400 | Q80028233 | ||
| Quantitative analysis of squalamine, a self-ionization-suppressing aminosterol sulfate, in human plasma by LC-MS/MS | Q80053062 | ||
| Ionizable isotopic labeling reagent for relative quantification of amine metabolites by mass spectrometry | Q80255711 | ||
| A study of common discovery dosing formulation components and their potential for causing time-dependent matrix effects in high-performance liquid chromatography tandem mass spectrometry assays | Q81119878 | ||
| Elimination of autosampler carryover in a bioanalytical HPLC-MS/MS method: a case study | Q81201629 | ||
| The use of turbulent flow chromatography and the isocratic focusing effect to achieve on-line cleanup and concentration of neat biological samples for low-level metabolite analysis | Q81380178 | ||
| Minimization of ion suppression in LC-MS/MS analysis through the application of strong cation exchange solid-phase extraction (SCX-SPE) | Q81397015 | ||
| Standard line slopes as a measure of a relative matrix effect in quantitative HPLC-MS bioanalysis | Q81535907 | ||
| Positive electrospray liquid chromatography/mass spectrometry using high-pH gradients: a way to combine selectivity and sensitivity for a large variety of drugs | Q81686377 | ||
| High-throughput quantification for a drug mixture in rat plasma-a comparison of Ultra Performance liquid chromatography/tandem mass spectrometry with high-performance liquid chromatography/tandem mass spectrometry | Q82288147 | ||
| A new approach for evaluating carryover and its influence on quantitation in high-performance liquid chromatography and tandem mass spectrometry assay | Q82414411 | ||
| Analysis of androgenic steroid Girard P hydrazones using multistage tandem mass spectrometry | Q82847611 | ||
| Direct sensitive quantitative lC/MS analysis of C-peptide from human urine by two dimensional reverse phase/reverse phase high-performance liquid chromatography | Q83050719 | ||
| Separation of a BMS drug candidate and acyl glucuronide from seven glucuronide positional isomers in rat plasma via high-performance liquid chromatography with tandem mass spectrometric detection | Q83290398 | ||
| Utility of porous graphitic carbon stationary phase in quantitative liquid chromatography/tandem mass spectrometry bioanalysis: quantitation of diastereomers in plasma | Q83358870 | ||
| Determination of a prostaglandin D2 antagonist and its acyl glucuronide metabolite in human plasma by high performance liquid chromatography with tandem mass spectrometric detection--a lack of MS/MS selectivity between a glucuronide conjugate and a | Q83824950 | ||
| LC/MS/MS analysis of quaternary ammonium drugs and herbicides in whole blood | Q83824960 | ||
| Sample to sample carryover: a source of analytical laboratory error and its relevance to integrated clinical chemistry/immunoassay systems | Q84001025 | ||
| P4510 | describes a project that uses | liquid chromatography–mass spectrometry | Q873864 |
| P433 | issue | 3 | |
| P304 | page(s) | 262-278 | |
| P577 | publication date | 2006-11-06 | |
| P1433 | published in | Journal of Pharmacological and Toxicological Methods | Q15724529 |
| P1476 | title | Tracking problems and possible solutions in the quantitative determination of small molecule drugs and metabolites in biological fluids using liquid chromatography-mass spectrometry | |
| P478 | volume | 55 |
| Q40635817 | A simple, effective approach for rapid development of high-throughput and reliable LC-MS/MS bioanalytical assays |
| Q36400366 | Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans |
| Q82433541 | Automated solid-phase microextraction and thin-film microextraction for high-throughput analysis of biological fluids and ligand-receptor binding studies |
| Q33748874 | Critical topics in ensuring data quality in bioanalytical LC-MS method development |
| Q52737161 | Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry. |
| Q49104142 | Evaluation of matrix effects in analysis of estrogen using liquid chromatography-tandem mass spectrometry. |
| Q39107323 | Hydrophilic interaction liquid chromatography coupled with MS/MS to detect and quantify dicarboxyethyl glutathione, a metabolic biomarker of the fumarate hydratase deficient cancer cell |
| Q38453213 | Making methods rugged for regulated bioanalysis |
| Q52345451 | Paper Spray Mass Spectrometry for High-Throughput Quantification of Nicotine and Cotinine. |
| Q34620942 | Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine |
| Q37671977 | Plant metabolomics--meeting the analytical challenges of comprehensive metabolite analysis |
| Q40111593 | Potential of monitoring isotopologues by quantitative gas chromatography with time-of-flight mass spectrometry for metabolomic assay |
| Q37810210 | Quantification of polar drugs in human plasma with liquid chromatography-tandem mass spectrometry |
| Q46897823 | Quantitative plasma analysis using automated online solid-phase extraction with column switching LC-MS/MS for characterising cytochrome P450 2D6 and 2C19 metabolism. |
| Q37693962 | Recent development in high-throughput bioanalytical support for in vitro ADMET profiling |
| Q51367228 | Systematic evaluation of the root cause of non-linearity in liquid chromatography/tandem mass spectrometry bioanalytical assays and strategy to predict and extend the linear standard curve range. |
| Q37855711 | The pivotal role of mass spectrometry in determining the presence of chemical contaminants in food raw materials |
| Q36730046 | Untargeted Metabolomics To Ascertain Antibiotic Modes of Action. |
| Q46271397 | Untargeted mass spectrometry discloses plasma solute levels poorly controlled by hemodialysis |
| Q45298385 | Use of high-resolution mass spectrometry to investigate a metabolite interference during liquid chromatography/tandem mass spectrometric quantification of a small molecule in toxicokinetic study samples |
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