Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo

scientific article published on 12 May 2008

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1049597613
P356DOI10.1186/1742-4690-5-38
P8608Fatcat IDrelease_ms562dkisbabvdt5wnqd5s4qw4
P932PMC publication ID2405800
P698PubMed publication ID18474092
P5875ResearchGate publication ID5377691

P2093author name stringPatrick L Green
Min Li
Michael D Lairmore
Matthew Kesic
Ihab Younis
Brenda Yamamoto
P2860cites workEmergence of unique primate T-lymphotropic viruses among central African bushmeat huntersQ24529110
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A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactionsQ28259102
Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domainQ33785291
Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivoQ33792918
Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFkappaB or CREB/ATF activation fail to transform primary human T cellsQ33799859
Human T-cell leukemia virus type 2 Rex protein increases stability and promotes nuclear to cytoplasmic transport of gag/pol and env RNAsQ33819203
Human T-lymphotropic virus type 1 p30(II) functions as a transcription factor and differentially modulates CREB-responsive promotersQ33827304
Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.Q33846963
Phosphorylation of two serine residues regulates human T-cell leukemia virus type 2 Rex functionQ33854182
Envelope is a major viral determinant of the distinct in vitro cellular transformation tropism of human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2.Q34142780
Human T-cell leukemia virus open reading frame II encodes a posttranscriptional repressor that is recruited at the level of transcription.Q34233092
Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.Q34334781
History of the discoveries of the first human retroviruses: HTLV-1 and HTLV-2.Q34450080
Discovery of HTLV-1, the first human retrovirus, its unique regulatory mechanisms, and insights into pathogenesisQ34450086
Integrated human T-cell leukemia virus II genome in CD8 + T cells from a patient with "atypical" hairy cell leukemia: evidence for distinct T and B cell lymphoproliferative disordersQ34553000
Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activityQ34605818
Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genesQ34626944
Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation.Q35829901
Time course and cytokine dependence of human T-cell lymphotropic virus type 1 T-lymphocyte transformation as revealed by a microtiter infectivity assay.Q35848268
Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.Q35848284
Human T-cell leukemia virus type 1 Tax transactivates the human proliferating cell nuclear antigen promoter.Q35876649
The HTLV-I Tax oncoprotein: hyper-tasking at the molecular levelQ35966311
Detection and quantitation of HTLV-1 and HTLV-2 mRNA species by real-time RT-PCR.Q36103218
The internal methionine codons of human T-cell leukemia virus type II rex gene are not required for p24rex production or virus replication and transformationQ36784089
Human T-cell lymphotropic virus type 1 open reading frame II-encoded p30II is required for in vivo replication: evidence of in vivo reversionQ37093163
Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type IQ37210537
Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulatorQ37568028
Tropical spastic paraparesis-like illness occurring in a patient dually infected with HIV-1 and HTLV-II.Q38905150
Spastic ataxia associated with human T-cell lymphotropic virus type II infectionQ39049930
Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.Q39577374
Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytesQ39578739
Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular cloneQ39594099
Functional analysis of human T-cell leukemia virus type I rex-response element: direct RNA binding of Rex protein correlates with in vivo activityQ40106375
Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replicationQ40159016
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replicationQ40598039
A deletion in the proximal untranslated pX region of human T-cell leukemia virus type II decreases viral replication but not infectivity in vivo.Q41235939
Expression and characterization of proteins produced by mRNAs spliced into the X region of the human T-cell leukemia/lymphotropic virus type II.Q41342684
PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivoQ41895077
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulationQ43574038
p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complexQ45271079
X-I and X-II open reading frames of HTLV-I are not required for virus replication or for immortalization of primary T-cells in vitroQ45759936
Molecular characterization of genome of a novel human T-cell leukaemia virusQ45797729
Chronic neurodegenerative disease associated with HTLV-II infection.Q45999329
HTLV-II-associated cutaneous T-cell lymphoma in a patient with HIV-1 infection.Q55240009
HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.Q55242466
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats.Q55244921
P921main subjectinfectivityQ1662346
T-cell leukemiaQ7667895
viral persistenceQ44134905
P304page(s)38
P577publication date2008-05-12
P1433published inRetrovirologyQ15793508
P1476titleHuman T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo
P478volume5

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cites work (P2860)
Q36299426Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses
Q92480985Comparative virology of HTLV-1 and HTLV-2
Q39392791Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2.
Q37646720Discovery and significance of new human T-lymphotropic viruses: HTLV-3 and HTLV-4.
Q35826764Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion
Q52619893Effects of sialidase knockout and complementation on virulence of Mycoplasma gallisepticum.
Q36694078Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis
Q38239657HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties.
Q24307735HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression
Q41811371HTLV-I p30: a versatile protein modulating virus replication and pathogenesis
Q36172168Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo
Q37945226Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.
Q35261449Orf-I and orf-II-encoded proteins in HTLV-1 infection and persistence.
Q93157476Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors
Q91831967The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-κB p65RelA-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability
Q26864846The need to accessorize: molecular roles of HTLV-1 p30 and HTLV-2 p28 accessory proteins in the viral life cycle

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