review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1038/NRI1997 |
P8608 | Fatcat ID | release_l4gspio57rej7po675j5y36jbu |
P698 | PubMed publication ID | 17186029 |
P2093 | author name string | Sanjeev Mariathasan | |
Denise M Monack | |||
P2860 | cites work | ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells | Q22010808 |
ICEBERG: a novel inhibitor of interleukin-1beta generation | Q24290437 | ||
Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis | Q24291258 | ||
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1 | Q24291293 | ||
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome | Q24291856 | ||
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines | Q24294720 | ||
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection | Q48108353 | ||
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila | Q48269403 | ||
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. | Q52190101 | ||
Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. | Q53944716 | ||
The inflammasome--a linebacker of innate defense. | Q55042326 | ||
Potassium regulates IL-1 beta processing via calcium-independent phospholipase A2 | Q73755857 | ||
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation | Q73867640 | ||
Inhibition of fas death signals by FLIPs | Q77485563 | ||
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules | Q80912569 | ||
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection | Q82412798 | ||
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing | Q24297724 | ||
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes | Q24298360 | ||
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta | Q24305136 | ||
Interleukin 1 is processed and released during apoptosis | Q24315035 | ||
Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC | Q24316380 | ||
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder | Q24317771 | ||
Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses | Q24337800 | ||
Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 | Q24531784 | ||
Toll-like receptor signalling | Q24570126 | ||
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis | Q24676746 | ||
Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity | Q25257710 | ||
Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 | ||
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis | Q28139969 | ||
Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing | Q28204263 | ||
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins | Q28215242 | ||
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice | Q28235461 | ||
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases | Q28263484 | ||
Inflammatory caspases and inflammasomes: master switches of inflammation | Q28263855 | ||
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf | Q28266417 | ||
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation | Q28283586 | ||
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme | Q28287610 | ||
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB | Q28289989 | ||
Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
Signalling pathways and molecular interactions of NOD1 and NOD2 | Q28298636 | ||
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock | Q28307404 | ||
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf | Q28506503 | ||
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1 | Q28512341 | ||
Altered cytokine production in mice lacking P2X(7) receptors | Q28586061 | ||
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin | Q28586508 | ||
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages | Q28594887 | ||
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1 | Q29614473 | ||
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 | Q29615598 | ||
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis | Q30668600 | ||
Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation | Q33604552 | ||
An exegesis of IAPs: salvation and surprises from BIR motifs | Q33688048 | ||
Caspase activation: the induced-proximity model | Q33740126 | ||
The inflammasome: first line of the immune response to cell stress | Q33998873 | ||
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. | Q34155136 | ||
Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release | Q34248184 | ||
Bacterial invasion: the paradigms of enteroinvasive pathogens | Q34312229 | ||
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island | Q34359740 | ||
Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population. | Q34389277 | ||
Salmonella interactions with host cells: type III secretion at work | Q34425135 | ||
NOD-LRR proteins: role in host-microbial interactions and inflammatory disease | Q34426050 | ||
Bacterial genomics and pathogen evolution | Q34497253 | ||
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival | Q34567790 | ||
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production | Q34684433 | ||
New insights into the mechanism of IL-1beta maturation | Q35031950 | ||
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection | Q35060264 | ||
The autoinflammatory syndromes | Q35643296 | ||
The role of Toll-like receptors and Nod proteins in bacterial infection | Q35914426 | ||
Leukocyte P2 receptors: a novel target for anti-inflammatory and anti-tumor therapy | Q36048104 | ||
NACHT-LRR proteins (NLRs) in bacterial infection and immunity | Q36182394 | ||
Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death | Q36278873 | ||
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis | Q36403658 | ||
Bacterial adhesion and entry into host cells | Q36404646 | ||
CATERPILLERs, pyrin and hereditary immunological disorders | Q36405072 | ||
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes | Q36448740 | ||
Intracellular pattern recognition receptors in the host response | Q36528528 | ||
Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense | Q36584966 | ||
Salmonella type III secretion-associated chaperones confer secretion-pathway specificity | Q38345198 | ||
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. | Q40394627 | ||
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis | Q40562330 | ||
A process for controlling intracellular bacterial infections induced by membrane injury | Q41462474 | ||
Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection | Q42566826 | ||
Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes | Q44187869 | ||
P433 | issue | 1 | |
P921 | main subject | inflammasome complex | Q412405 |
P304 | page(s) | 31-40 | |
P577 | publication date | 2007-01-01 | |
P1433 | published in | Nature Reviews Immunology | Q43355 |
P1476 | title | Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation | |
P478 | volume | 7 |