| P2093 | author name string | Sanjeev Mariathasan | |
| | Denise M Monack | |
| P2860 | cites work | ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells | Q22010808 |
| | ICEBERG: a novel inhibitor of interleukin-1beta generation | Q24290437 |
| | Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis | Q24291258 |
| | Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1 | Q24291293 |
| | Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome | Q24291856 |
| | IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines | Q24294720 |
| | A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection | Q48108353 |
| | Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila | Q48269403 |
| | Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. | Q52190101 |
| | Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. | Q53944716 |
| | The inflammasome--a linebacker of innate defense. | Q55042326 |
| | Potassium regulates IL-1 beta processing via calcium-independent phospholipase A2 | Q73755857 |
| | Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation | Q73867640 |
| | Inhibition of fas death signals by FLIPs | Q77485563 |
| | ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules | Q80912569 |
| | The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection | Q82412798 |
| | PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing | Q24297724 |
| | Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes | Q24298360 |
| | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta | Q24305136 |
| | Interleukin 1 is processed and released during apoptosis | Q24315035 |
| | Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC | Q24316380 |
| | NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder | Q24317771 |
| | Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses | Q24337800 |
| | Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 | Q24531784 |
| | Toll-like receptor signalling | Q24570126 |
| | Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis | Q24676746 |
| | Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity | Q25257710 |
| | Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 |
| | A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis | Q28139969 |
| | Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing | Q28204263 |
| | Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins | Q28215242 |
| | Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice | Q28235461 |
| | Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases | Q28263484 |
| | Inflammatory caspases and inflammasomes: master switches of inflammation | Q28263855 |
| | Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf | Q28266417 |
| | INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation | Q28283586 |
| | Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme | Q28287610 |
| | Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB | Q28289989 |
| | Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 |
| | Signalling pathways and molecular interactions of NOD1 and NOD2 | Q28298636 |
| | Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock | Q28307404 |
| | Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf | Q28506503 |
| | The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1 | Q28512341 |
| | Altered cytokine production in mice lacking P2X(7) receptors | Q28586061 |
| | Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin | Q28586508 |
| | Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages | Q28594887 |
| | Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1 | Q29614473 |
| | Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 | Q29615598 |
| | CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis | Q30668600 |
| | Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation | Q33604552 |
| | An exegesis of IAPs: salvation and surprises from BIR motifs | Q33688048 |
| | Caspase activation: the induced-proximity model | Q33740126 |
| | The inflammasome: first line of the immune response to cell stress | Q33998873 |
| | Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. | Q34155136 |
| | Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release | Q34248184 |
| | Bacterial invasion: the paradigms of enteroinvasive pathogens | Q34312229 |
| | Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island | Q34359740 |
| | Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population. | Q34389277 |
| | Salmonella interactions with host cells: type III secretion at work | Q34425135 |
| | NOD-LRR proteins: role in host-microbial interactions and inflammatory disease | Q34426050 |
| | Bacterial genomics and pathogen evolution | Q34497253 |
| | Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival | Q34567790 |
| | The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production | Q34684433 |
| | New insights into the mechanism of IL-1beta maturation | Q35031950 |
| | Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection | Q35060264 |
| | The autoinflammatory syndromes | Q35643296 |
| | The role of Toll-like receptors and Nod proteins in bacterial infection | Q35914426 |
| | Leukocyte P2 receptors: a novel target for anti-inflammatory and anti-tumor therapy | Q36048104 |
| | NACHT-LRR proteins (NLRs) in bacterial infection and immunity | Q36182394 |
| | Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death | Q36278873 |
| | Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis | Q36403658 |
| | Bacterial adhesion and entry into host cells | Q36404646 |
| | CATERPILLERs, pyrin and hereditary immunological disorders | Q36405072 |
| | Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes | Q36448740 |
| | Intracellular pattern recognition receptors in the host response | Q36528528 |
| | Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense | Q36584966 |
| | Salmonella type III secretion-associated chaperones confer secretion-pathway specificity | Q38345198 |
| | Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. | Q40394627 |
| | Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis | Q40562330 |
| | A process for controlling intracellular bacterial infections induced by membrane injury | Q41462474 |
| | Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection | Q42566826 |
| | Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes | Q44187869 |
| P433 | issue | 1 | |
| P921 | main subject | inflammasome complex | Q412405 |
| P304 | page(s) | 31-40 | |
| P577 | publication date | 2007-01-01 | |
| P1433 | published in | Nature Reviews Immunology | Q43355 |
| P1476 | title | Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation | |
| P478 | volume | 7 | |