Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy

scientific article published on March 2008

Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.180.5.2981
P932PMC publication ID2408862
P698PubMed publication ID18292520
P5875ResearchGate publication ID5558784

P50authorBruce R BlazarQ62070764
Douglas D. RedelmanQ86539902
William J. MurphyQ91170042
Lisbeth A. WelniakQ104889873
P2093author name stringQing Zhou
Jonathan M Weiss
Robert H Wiltrout
Kory L Alderson
Danice E C Wilkins
Vanessa Berner
P2860cites workPD-1 and its ligands in T-cell immunityQ36791446
IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapyQ40164065
Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell HelpQ42642562
Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virusQ45408162
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.Q46028085
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanismQ47745301
RNA fingerprints provide direct evidence for the inhibitory role of TGF and PD-1 on CD4+ T cells in Hodgkin lymphomaQ57556410
Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responsesQ73020219
B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allograftsQ79287397
TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cellsQ79834632
Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathwayQ80092442
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell deathQ24293504
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activationQ24675931
Antiviral CD4+ memory T cells are IL-15 dependentQ24676283
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasionQ28131654
CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.Q34063120
Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell MemoryQ34190038
CD4+ PD-1+ T cells accumulate as unique anergic cells in rheumatoid arthritis synovial fluid.Q34535434
PD-L2+ dendritic cells and PD-1+ CD4+ T cells in schistosomiasis correlate with morbidityQ34556528
Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigensQ34572972
PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressorsQ34574649
Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergyQ34575119
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cellsQ34578170
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cellsQ34600272
The new B7s: playing a pivotal role in tumor immunityQ34616690
Tregs and rethinking cancer immunotherapyQ34625147
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockadeQ34657684
New regulatory co-receptors: inducible co-stimulator and PD-1.Q34987302
The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cellsQ35578758
The roles of the new negative T cell costimulatory pathways in regulating autoimmunityQ35772868
CD4 cells can be more efficient at tumor rejection than CD8 cellsQ35839925
Expression of the programmed death ligand 1, B7-H1, on gastric epithelial cells after Helicobacter pylori exposure promotes development of CD4+ CD25+ FoxP3+ regulatory T cellsQ35947323
Tissue expression of PD-L1 mediates peripheral T cell tolerance.Q36228541
Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasisQ36403813
Role of TCR specificity in CD4+ CD25+ regulatory T-cell selectionQ36563507
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune diseaseQ36747499
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
P304page(s)2981-2988
P577publication date2008-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleRegulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy
P478volume180

Reverse relations

cites work (P2860)
Q37783268Antigen Specific Memory T Cells and Their Putative Need for the Generation of Sustained Anti-Tumor Responses
Q33866065Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis
Q33381270Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells
Q35876982Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy
Q33631222Dendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model.
Q33572965Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy
Q30157046Feline programmed death and its ligand: characterization and changes with feline immunodeficiency virus infection
Q34429197Immune Sculpting of Norepinephrine on MHC-I, B7-1, IDO and B7-H1 Expression and Regulation of Proliferation and Invasion in Pancreatic Carcinoma Cells
Q36380188Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects
Q34563034Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells.
Q42277216Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function.
Q33604484Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette
Q42365163PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients
Q33723734Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy
Q37129619Regulatory T cells in systemic lupus erythematosus: past, present and future
Q37412903Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment
Q38026924The Use of Agonistic Anti-CD40 Therapy in Treatments for Cancer

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