| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2013PNAS..110E.996W |
| P356 | DOI | 10.1073/PNAS.1214875110 |
| P932 | PMC publication ID | 3600500 |
| P698 | PubMed publication ID | 23431135 |
| P5875 | ResearchGate publication ID | 235691682 |
| P2093 | author name string | David Fedida | |
| Zhuren Wang | |||
| Jodene Eldstrom | |||
| Daniel Werry | |||
| P2860 | cites work | Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel | Q24292184 |
| Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias | Q24311437 | ||
| Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel | Q24318271 | ||
| Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells | Q39945565 | ||
| Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels | Q40228821 | ||
| Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation. | Q42441516 | ||
| Multiple conductances in the large K+ channel from Chara corallina shown by a transient analysis method | Q42581161 | ||
| Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter | Q42613991 | ||
| Gating properties of inward-rectifier potassium channels: effects of permeant ions | Q43785725 | ||
| Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes. | Q44486244 | ||
| Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle. | Q46675989 | ||
| Mutation in the KCNQ1 gene leading to the short QT-interval syndrome | Q47438291 | ||
| Multiple gating modes and the effect of modulating factors on the μI sodium channel | Q48636805 | ||
| Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels | Q48745779 | ||
| Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B. | Q48985465 | ||
| Increase of the single-channel conductance of KvLQT1 potassium channels induced by the association with minK. | Q50741839 | ||
| Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. | Q51809148 | ||
| Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed. | Q52480990 | ||
| Stochastic Properties of Ion Channel Openings and Bursts in a Membrane Patch that Contains Two Channels: Evidence Concerning the Number of Channels Present when a Record Containing Only Single Openings is Observed | Q57908067 | ||
| A reinterpretation of mammalian sodium channel gating based on single channel recording | Q59062717 | ||
| KCNQ1 gain-of-function mutation in familial atrial fibrillation | Q24338486 | ||
| Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels | Q24642407 | ||
| Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions | Q24642455 | ||
| K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current | Q28295470 | ||
| KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate | Q28300574 | ||
| A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B | Q28366030 | ||
| Stoichiometry of the KCNQ1 - KCNE1 ion channel complex. | Q28583726 | ||
| Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity | Q33175234 | ||
| Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs. | Q33814293 | ||
| Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating | Q33916837 | ||
| Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events | Q34016948 | ||
| A geometric sequence that accurately describes allowed multiple conductance levels of ion channels: the "three-halves (3/2) rule" | Q34018358 | ||
| Gating of I(sK) channels expressed in Xenopus oocytes | Q34167776 | ||
| Activation and inactivation of homomeric KvLQT1 potassium channels. | Q34168644 | ||
| A direct optimization approach to hidden Markov modeling for single channel kinetics | Q34174076 | ||
| Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling | Q34184964 | ||
| Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis | Q34568142 | ||
| KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity | Q35021903 | ||
| Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve | Q35676902 | ||
| Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels | Q35935730 | ||
| Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels. | Q36266824 | ||
| Shaker potassium channel gating. I: Transitions near the open state | Q36411424 | ||
| Shaker potassium channel gating. III: Evaluation of kinetic models for activation | Q36411441 | ||
| Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents | Q36434545 | ||
| Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels | Q36436105 | ||
| Single-channel properties of IKs potassium channels | Q36436185 | ||
| Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome | Q36436190 | ||
| Selectivity changes during activation of mutant Shaker potassium channels | Q36445050 | ||
| K channel subconductance levels result from heteromeric pore conformations | Q36493498 | ||
| Slow delayed rectifier potassium current (IKs) and the repolarization reserve. | Q36730716 | ||
| Fluorescence detection of the movement of single KcsA subunits reveals cooperativity. | Q37068443 | ||
| Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes | Q37678024 | ||
| Ion channel subconductance states | Q38177363 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | E996-1005 | |
| P577 | publication date | 2013-02-19 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I(Ks) | |
| P478 | volume | 110 |
| Q57187143 | Effects of β-subunit on gating of a potassium ion channel: Molecular simulations of cardiac IKs activation |
| Q28551018 | Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition |
| Q92658083 | I Ks ion-channel pore conductance can result from individual voltage sensor movements |
| Q47127280 | Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening |
| Q37028794 | KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulation |
| Q33603925 | KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps |
| Q46181904 | KCNQ1 autoantibodies: another way to regulate IKs. |
| Q27027928 | KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain |
| Q89419570 | Modeling the Hidden Pathways of IKs Channel Activation |
| Q38696328 | Photo-Cross-Linking of IKs Demonstrates State-Dependent Interactions between KCNE1 and KCNQ1. |
| Q44505007 | Potassium channels in the heart: structure, function and regulation. |
| Q38632751 | Purification and structural study of the voltage-sensor domain of the human KCNQ1 potassium ion channel |
| Q90358793 | Single channel kinetic analysis of the cAMP effect on IKs mutants, S209F and S27D/S92D |
| Q53042866 | Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening. |
| Q57490689 | The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry |
| Q90399746 | The KV 7 channel activator retigabine suppresses mouse urinary bladder afferent nerve activity without affecting detrusor smooth muscle K+ channel currents |
| Q62495888 | The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations |
| Q43116071 | Understanding the microscopic mechanisms for LQT1 needs a global view of the I(Ks) channel |
| Q39477676 | Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4. |
| Q90095358 | Upgraded molecular models of the human KCNQ1 potassium channel |
| Q38690407 | Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels |
| Q38688887 | cAMP-dependent regulation of IKs single-channel kinetics |
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