| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1993PNAS...9011262S |
| P356 | DOI | 10.1073/PNAS.90.23.11262 |
| P932 | PMC publication ID | 47962 |
| P698 | PubMed publication ID | 8248238 |
| P5875 | ResearchGate publication ID | 14951529 |
| P50 | author | Dominic J Wells | Q37380873 |
| Paresh Vyas | Q47451425 | ||
| P2093 | author name string | D R Higgs | |
| W G Wood | |||
| J A Sharpe | |||
| E Whitelaw | |||
| P2860 | cites work | In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction | Q24630435 |
| Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
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| A review of the molecular genetics of the human alpha-globin gene cluster | Q28268949 | ||
| Position-independent, high-level expression of the human beta-globin gene in transgenic mice | Q29620032 | ||
| An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes | Q33849519 | ||
| Inactivation of human alpha-globin gene expression by a de novo deletion located upstream of the alpha-globin gene cluster | Q33919342 | ||
| Detailed analysis of the site 3 region of the human beta-globin dominant control region | Q33920690 | ||
| Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice | Q33938795 | ||
| A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin | Q34249835 | ||
| Molecular analysis of the human beta-globin locus activation region | Q34290946 | ||
| Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites | Q34307556 | ||
| DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression | Q35845673 | ||
| Developmental regulation of the human zeta globin gene in transgenic mice | Q35892335 | ||
| The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites | Q35925421 | ||
| The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene | Q35933226 | ||
| Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids | Q36102094 | ||
| δβ Thalassemia and Hereditary Persistence of Fetal Hemoglobin | Q36670384 | ||
| Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice | Q36726619 | ||
| A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice | Q36814647 | ||
| Characterization of the major regulatory element upstream of the human alpha-globin gene cluster | Q40640470 | ||
| Regulation of human embryonic globin genes zeta 2 and epsilon in stably transformed mouse erythroleukemia cells | Q41601311 | ||
| Recombination at the human alpha-globin gene cluster: sequence features and topological constraints | Q42012580 | ||
| A dominant control region from the human beta-globin locus conferring integration site-independent gene expression | Q45885783 | ||
| The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions | Q47617863 | ||
| Identification of two distinct regulatory regions adjacent to the human β-interferon gene | Q48395961 | ||
| Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice | Q52229892 | ||
| A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n | Q56550729 | ||
| Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster | Q56550741 | ||
| β-Globin gene inactivation by DNA translocation in γβ-thalassaemi | Q56969774 | ||
| Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression | Q64008535 | ||
| Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes. | Q64922797 | ||
| In situ hybridization reveals co-expression of embryonic and adult alpha globin genes in the earliest murine erythrocyte progenitors | Q67824548 | ||
| A major positive regulatory region located far upstream of the human alpha-globin gene locus | Q68624475 | ||
| Rapid reprogramming of globin gene expression in transient heterokaryons | Q69566352 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 11262-11266 | |
| P577 | publication date | 1993-12-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Analysis of the human alpha-globin gene cluster in transgenic mice | |
| P478 | volume | 90 |
| Q38325962 | A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene |
| Q40792436 | A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice |
| Q36566098 | A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene. |
| Q34594033 | Age-dependent silencing of globin transgenes in the mouse |
| Q40522257 | Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice |
| Q39720574 | Analysis of enhancer function of the HS-40 core sequence of the human alpha-globin cluster |
| Q39715344 | CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells |
| Q41875311 | Chromatin interaction mechanism of transcriptional control in vivo |
| Q73401652 | Coactivation of human alpha1- and alpha2-globin genes in single induced MEL cells containing one human alpha-globin locus |
| Q40806429 | Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments |
| Q33757285 | DNA methylation in zebrafish |
| Q36753290 | Derepression of human embryonic zeta-globin promoter by a locus-control region sequence |
| Q38298122 | Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability |
| Q36559963 | Developmental silencing of the embryonic zeta-globin gene: concerted action of the promoter and the 3'-flanking region combined with stage-specific silencing by the transcribed segment |
| Q33598595 | Differences of globin transgene expression in stably transfected cell lines and transgenic mice |
| Q36567019 | Expression of the chicken beta-globin gene cluster in mice: correct developmental expression and distributed control |
| Q38296623 | Functional roles of in vivo footprinted DNA motifs within an alpha-globin enhancer. Erythroid lineage and developmental stage specificities |
| Q35644736 | Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans |
| Q34193437 | Mammalian linker-histone subtypes differentially affect gene expression in vivo |
| Q34719514 | Molecular aspects of embryonic hemoglobin function |
| Q50093958 | Mouse Models of Erythropoiesis and Associated Diseases. |
| Q34768410 | Position independent expression and developmental regulation is directed by the β myosin heavy chain gene's 5′ upstream region in transgenic mice |
| Q34216010 | Position-dependent variegation of globin transgene expression in mice |
| Q34616581 | Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice |
| Q44031048 | Repeat-induced gene silencing in mammals. |
| Q44461749 | Sensitive flow cytometric analysis reveals a novel type of parent-of-origin effect in the mouse genome |
| Q38900001 | Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease |
| Q34039291 | Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity |
| Q74095575 | Spontaneous germline amplification and translocation of a transgene array |
| Q35038968 | The control of expression of the alpha-globin gene cluster |
| Q31032474 | The expression of human alpha -like globin genes in transgenic mice mediated by bacterial artificial chromosome. |
| Q41491633 | The role of mRNA stability in the control of globin gene expression. |
| Q37087628 | The role of the epigenetic signal, DNA methylation, in gene regulation during erythroid development. |
| Q34194830 | Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease |
| Q34128509 | Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells |
| Q34731252 | Transgenerational analysis of transcriptional silencing in zebrafish |
| Q35351225 | Uncovering enhancer functions using the α-globin locus |
| Q46130409 | cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation |
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