Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid

scientific article published on September 1, 1992

Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.12.9.3819
10.1128/MCB.12.9.3819-3826.1992
P953full work available at URLhttp://mcb.asm.org/cgi/content/abstract/12/9/3819
https://europepmc.org/articles/PMC360251
https://europepmc.org/articles/PMC360251?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1380647/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1380647/pdf/?tool=EBI
P932PMC publication ID360251
P698PubMed publication ID1380647
P5875ResearchGate publication ID21774360

P2093author name stringT. Sasaki
R. S. Hansen
S. M. Gartler
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Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesisQ24629611
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". AddendumQ27860612
CpG-rich islands and the function of DNA methylationQ28131800
DNA Methylation and Gene FunctionQ28263722
Gene action in the X-chromosome of the mouse (Mus musculus L.)Q29618263
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG islandQ33608890
Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNAQ33647093
Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stabilityQ33859871
Isolation of mammalian cell mutants deficient in glucose-6-phosphate dehydrogenase activity: linkage to hypoxanthine phosphoribosyl transferaseQ35069238
Genes controlling gp25/30 cell-surface molecules map to chromosomes X and Y and escape X-inactivationQ35200186
Chromatin structure of active and inactive human X chromosomesQ35265096
X chromosome inactivation of the human TIMP gene.Q35851082
Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNAQ35977023
Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomesQ36255574
Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivationQ36259490
Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidineQ36282892
Transformation with DNA from 5-azacytidine-reactivated X chromosomesQ36290263
Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferaseQ36308497
Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expressionQ36848582
Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinaseQ36900596
Hemimethylation of DNA prevents chromatin expressionQ37706115
Assembly of an active chromatin structure during replicationQ40503069
High-Frequency Conversion to a “Fluffy” Developmental Phenotype in Aspergillus spp. by 5-Azacytidine Treatment: Evidence for Involvement of a Single Nuclear GeneQ40680717
Mammalian X chromosome inactivation: testing the hypothesis of transcriptional control.Q41444741
Chromatin differences between active and inactive X chromosomes revealed by genomic footprinting of permeabilized cells using DNase I and ligation-mediated PCR.Q41680577
DNA methylation of two X chromosome genes in female somatic and embryonal carcinoma cellsQ41701610
DNA methylation affects the formation of active chromatinQ44614953
Chromosomal subunits in active genes have an altered conformationQ44733420
Specific protection of methylated CpGs in mammalian nucleiQ45193660
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGsQ48289947
Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genesQ59057684
DNA methylation inhibits transcription indirectly via a methyl-CpG binding proteinQ64441635
Dynamics of demethylation and activation of the alpha-actin gene in myoblastsQ68636634
A two step model for mammalian X-chromosome inactivationQ68948638
High-frequency reactivation of X-linked genes in Chinese hamster X human hybrid cellsQ68997841
Methylation of the Hprt gene on the inactive X occurs after chromosome inactivationQ69687603
Comparative study of DNase I sensitivity at the X-linked human HPRT locusQ69826756
Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylationQ72632603
Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNAQ72693089
Derepression of genes on the human inactive X chromosome: evidence for differences in locus-specific rates of derepression and rates of transfer of active and inactive genes after DNA-mediated transformationQ77225234
Chapter 3: Production and Characterization of Mammalian Cells Reversibly Arrested in G1 by Growth in Isoleucine-Deficient MediumQ93749548
P433issue9
P407language of work or nameEnglishQ1860
P921main subjecttranscriptionQ177900
dosage compensationQ13417137
P304page(s)3819-3826
P577publication date1992-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleHemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid
P478volume12

Reverse relations

cites work (P2860)
Q411055285-Azadeoxycytidine-induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation
Q51984888Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
Q36560044Cell-specific transcriptional regulation and reactivation of galectin-1 gene expression are controlled by DNA methylation of the promoter region.
Q34290287Chromatin alteration, transcription and replication: What's the opening line to the story?
Q34828632DNA methylation in transcriptional repression of two differentially expressed X-linked genes, GPC3 and SYBL1.
Q40455802Enhanced insulin secretion from engineered 3T3-L1 preadipocytes by induction of cellular differentiation.
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Q40868842In vitro reactivation of the FMR1 gene involved in fragile X syndrome
Q40656903Inactive chromatin spreads from a focus of methylation
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