Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?

scientific article published on 16 October 2015

Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00618.2015
P932PMC publication ID4796631
P698PubMed publication ID26475588

P2093author name stringMark C Chappell
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Subcellular characteristics of functional intracellular renin-angiotensin systems.Q30417227
Identification and characterization of a functional mitochondrial angiotensin systemQ30427934
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Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).Q44518988
NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin systemQ44590322
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True versus immunoreactive angiotensin II in human plasma.Q45018550
Conversion of renin substrate tetradecapeptide to angiotensin II by rat MAB elastase-2.Q45220362
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ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetesQ46782071
Evidence supporting a functional role for intracellular renin in the brainQ46919174
Immunocapture-based fluorometric assay for the measurement of neprilysin-specific enzyme activity in brain tissue homogenates and cerebrospinal fluidQ46975126
Increased expression of angiotensin peptides in the brain of transgenic hypertensive ratsQ48218404
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Reassessment of plasma angiotensins measurement: Effects of protease inhibitors and sample handling proceduresQ48667993
Development of a sensitive, accurate and robust liquid chromatography/mass spectrometric method for profiling of angiotensin peptides in plasma and its application for atherosclerotic mice.Q50995177
Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides.Q51022226
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Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study.Q52855193
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Reproducibility crisis: Blame it on the antibodiesQ59060328
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Angiotensinases restrict locally generated angiotensin II to the blood vessel wall.Q64964448
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Cardiac interstitial fluid levels of angiotensin I and II in the pigQ73513629
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Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjectsQ74385757
HPLC in the analysis of peptide metabolismQ75220527
Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive ratsQ77764371
Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin IIQ80077979
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Long-term AT1 receptor blockade improves metabolic function and provides renoprotection in Fischer-344 ratsQ80580056
Urinary angiotensinogen as a novel biomarker of the intrarenal renin-angiotensin system status in hypertensive patientsQ37135790
Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heartQ37175696
Augmentation of endogenous intrarenal angiotensin II levels in Val5-ANG II-infused ratsQ37190278
The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleusQ37208119
Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide productionQ37216933
Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidneyQ37324997
Detecting low-abundance vasoactive peptides in plasma: progress toward absolute quantitation using nano liquid chromatography-mass spectrometry.Q37350114
Association of elevated urinary concentration of renin-angiotensin system components and severe AKI.Q37359056
Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spacesQ37369862
A renin transcript lacking exon 1 encodes for a non-secretory intracellular renin that increases aldosterone production in transgenic ratsQ37398281
Estimation of angiotensin peptides in biological samples by LC/MS methodQ37523322
Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarctionQ37656079
Mast cell proteases as protective and inflammatory mediatorsQ37895550
New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axisQ37982718
The intracrine renin-angiotensin systemQ38010459
Angiotensin II generation in vivo: does it involve enzymes other than renin and angiotensin-converting enzyme?Q38012946
Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system.Q38054993
Urinary markers of intrarenal renin-angiotensin system activity in vivoQ38072329
Angiotensin-(1-7).Q38198985
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system.Q38230104
MAS and its related G protein-coupled receptors, Mrgprs.Q38253170
Hypertension: renin-angiotensin-aldosterone system alterationsQ38376304
Discovery and characterization of alamandine: a novel component of the renin-angiotensin systemQ39187631
Cytosolic renin is targeted to mitochondria and induces apoptosis in H9c2 rat cardiomyoblastsQ39955247
Intrarenal production of angiotensin II.Q41605108
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic miceQ41704433
Absolute quantification of endogenous angiotensin II levels in human plasma using ESI-LC-MS/MS.Q41995755
Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertensionQ42229346
Renal interstitial fluid concentrations of angiotensins I and II in anesthetized ratsQ42515936
Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibitionQ42525086
Functional intracellular renin-angiotensin systems: potential for pathophysiology of diseaseQ42570286
Recombinant Expression and Characterization of Human and Murine ACE2: Species-Specific Activation of the Alternative Renin-Angiotensin-SystemQ42589155
High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1-7) levels in the adipose tissue.Q43117155
Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memoryQ43297455
Measurement of immunoreactive angiotensin-(1-7) heptapeptide in human blood.Q43556507
Big angiotensin-25: a novel glycosylated angiotensin-related peptide isolated from human urineQ43799197
Intrarenal angiotensin II: interstitial and cellular levels and site of productionQ43818237
P433issue2
P304page(s)H137-52
P577publication date2015-10-16
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleBiochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
P478volume310

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