Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

scientific article published on 18 March 2016

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance is …
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scholarly articleQ13442814

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P819ADS bibcode2016NatCo...711030K
P356DOI10.1038/NCOMMS11030
P932PMC publication ID4802085
P698PubMed publication ID26988023
P5875ResearchGate publication ID298914136

P50authorMakoto SuematsuQ11519745
Takanori NakaneQ56987718
Takeshi UchidaQ61093964
Koichiro IshimoriQ55664881
Susumu UchiyamaQ56285607
Kenji SugaseQ47126377
P2093author name stringYuki Yamaguchi
Hiroshi Handa
Erisa Harada
Masanori Noda
So Iwata
Tatsuro Shimamura
Takuya Kobayashi
Tatsuya Yamamoto
Yuki Sugiura
Ayumi Yamamoto
Yasuaki Kabe
Elena Krayukhina
Mitsuyo Ohmura
Ikko Koike
Kazumi Muraoka
P2860cites workProgesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 ReductaseQ24307533
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Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumorsQ34656815
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Progesterone receptor membrane component-1 (PGRMC1) and PGRMC-2 interact to suppress entry into the cell cycle in spontaneously immortalized rat granulosa cellsQ35617036
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Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patientsQ39473591
Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cellsQ39627053
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectprotein homodimerization activityQ14762996
Progesterone receptor membrane component 1Q21110724
P304page(s)11030
P577publication date2016-03-18
P1433published inNature CommunicationsQ573880
P1476titleHaem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
P478volume7