| scholarly article | Q13442814 |
| P2093 | author name string | Hans B Sieburg | |
| Rebecca H Cho | |||
| Christa E Muller-Sieburg | |||
| P2860 | cites work | Evidence for a continuous decline in haemopoietic cell function from birth: application to evaluating bone marrow failure in children | Q28141910 |
| Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age | Q28505636 | ||
| DNA repair is limiting for haematopoietic stem cells during ageing | Q28509105 | ||
| Genetic regulation of primitive hematopoietic stem cell senescence | Q33180235 | ||
| Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics | Q33195768 | ||
| Hematopoietic stem cells do not engraft with absolute efficiencies | Q33224560 | ||
| Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation | Q33293158 | ||
| Cell intrinsic alterations underlie hematopoietic stem cell aging. | Q33858894 | ||
| Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy | Q33888454 | ||
| Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element | Q33935807 | ||
| T cell senescence | Q34136955 | ||
| Genetic dissection of age-related changes of immune function in mice. | Q34299824 | ||
| Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness | Q34299987 | ||
| The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets | Q34468106 | ||
| Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging | Q81212657 | ||
| The aging of lympho-hematopoietic stem cells | Q34580295 | ||
| Normal Production of Erythrocytes by Mouse Marrow Continuous for 73 Months | Q34743374 | ||
| Long-term propagation of distinct hematopoietic differentiation programs in vivo | Q34764957 | ||
| Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells | Q35848036 | ||
| An X chromosome gene regulates hematopoietic stem cell kinetics | Q36011518 | ||
| Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells | Q36175679 | ||
| Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice | Q36351106 | ||
| Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus | Q36354986 | ||
| Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1. | Q36365836 | ||
| Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene | Q36380554 | ||
| Clonal diversity of the stem cell compartment | Q36497990 | ||
| The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice | Q38305833 | ||
| Major age-related changes of mouse hematopoietic stem/progenitor cells | Q38520181 | ||
| High frequency of long-term culture-initiating cells retain in vivo repopulation and self-renewal capacity | Q40852277 | ||
| Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations. | Q40871580 | ||
| Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: effect of stromal cells and c-kit | Q41578714 | ||
| Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity. | Q42651447 | ||
| SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity | Q42741711 | ||
| Age-associated characteristics of murine hematopoietic stem cells | Q42944325 | ||
| Impaired thymic regeneration in lethally irradiated mice given bone marrow from aged donors | Q43483506 | ||
| Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient | Q44979914 | ||
| Quantitative genetic variation in the hematopoietic stem cell and progenitor cell compartment and in lifespan are closely linked at multiple loci in BXD recombinant inbred mice | Q45873303 | ||
| Deterministic regulation of hematopoietic stem cell self-renewal and differentiation. | Q46163240 | ||
| Early steps in T cell development are affected by aging | Q46774287 | ||
| The aging of hematopoietic stem cells | Q46785776 | ||
| The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors | Q47677663 | ||
| Il-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice. | Q51070899 | ||
| Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11. | Q52119113 | ||
| Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy. | Q52127742 | ||
| Independent homeostatic regulation of B cell compartments. | Q52193828 | ||
| Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by competitive limiting dilution analysis in vivo. | Q52200969 | ||
| Clonal and systemic analysis of long-term hematopoiesis in the mouse. | Q52242510 | ||
| Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a | Q57277034 | ||
| Bone marrow cells give rise to distinct cell clones within the thymus | Q59061614 | ||
| Quantitative analysis of bone marrow thymic progenitors in young and aged mice | Q68759372 | ||
| Effect of 5-fluorouracil on "primitive" hematopoietic stem cells that reconstitute whole erythropoiesis of genetically anemic W/Wv mice | Q69367570 | ||
| Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age | Q69369529 | ||
| Cycle initiation and colony formation in culture by murine marrow cells with long-term reconstituting potential in vivo | Q71834764 | ||
| Hematopoiesis in the aged: a model of hematopoietic dysregulation? | Q72553947 | ||
| Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors | Q73064327 | ||
| Reversible expression of CD34 by murine hematopoietic stem cells | Q73070185 | ||
| B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered expression of Bcl-2 family members | Q73119263 | ||
| Telomerase activity in candidate stem cells from fetal liver and adult bone marrow | Q74477777 | ||
| Maximum life spans in mice are extended by wild strain alleles | Q74543070 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5553-5561 | |
| P577 | publication date | 2008-04-15 | |
| P1433 | published in | Blood | Q885070 |
| P1476 | title | A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells | |
| P478 | volume | 111 |
| Q91639484 | A mathematical solution to Peto's paradox using Polya's urn model: implications for the aetiology of cancer in general |
| Q34522072 | A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampus |
| Q34106843 | Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity |
| Q29248538 | Accumulation of DNA damage in the aged hematopoietic stem cell compartment |
| Q27022410 | Age-dependent dysregulation of innate immunity |
| Q38214091 | Age-related Deterioration of Hematopoietic Stem Cells. |
| Q34004237 | Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors |
| Q37395779 | Age-related mutations and chronic myelomonocytic leukemia. |
| Q38425579 | Ageing and the immune system: focus on macrophages |
| Q36767874 | Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers |
| Q36528869 | Aging and neoteny in the B lineage |
| Q38600459 | Aging, clonal hematopoiesis and preleukemia: not just bad luck? |
| Q38921842 | Aging, inflammation, immunity and periodontal disease |
| Q35188247 | Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection? |
| Q37319929 | Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal. |
| Q37690603 | Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy |
| Q34986162 | Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice |
| Q54979332 | Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion. |
| Q64094881 | B Cell Dysfunction Associated With Aging and Autoimmune Diseases |
| Q36018760 | BMP signalling differentially regulates distinct haematopoietic stem cell types |
| Q36642445 | Bone marrow fat and the decline of B lymphopoiesis in rabbits |
| Q37256234 | CD137 ligand reverse signaling skews hematopoiesis towards myelopoiesis during aging |
| Q64098544 | Causes and Mechanisms of Hematopoietic Stem Cell Aging |
| Q36638131 | Causes, consequences, and reversal of immune system aging |
| Q33753610 | Cdc42 and aging of hematopoietic stem cells |
| Q37962262 | Cell cycle regulation in hematopoietic stem cells |
| Q33389973 | Cell therapy, a new standard in management of chronic critical limb ischemia and foot ulcer. |
| Q34037439 | Cells derived from young bone marrow alleviate renal aging |
| Q51594913 | Cellular aging leads to functional heterogeneity of hematopoietic stem cells: a modeling perspective. |
| Q37621477 | Changes in the frequencies of human hematopoietic stem and progenitor cells with age and site |
| Q37003488 | Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach |
| Q34907233 | Chronic exposure to a TLR ligand injures hematopoietic stem cells |
| Q36176981 | Chronic inflammation and aging: DNA damage tips the balance |
| Q39948728 | Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells |
| Q36287218 | Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate |
| Q60919757 | Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation |
| Q35001363 | Concise review: hematopoietic stem cell aging and the prospects for rejuvenation |
| Q36861673 | Concise review: hematopoietic stem cell aging, life span, and transplantation |
| Q38036830 | DNA damage checkpoints in stem cells, ageing and cancer. |
| Q41511457 | Discriminating cellular heterogeneity using microwell-based RNA cytometry |
| Q30493635 | Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. |
| Q38254580 | Early B lymphocyte development: Similarities and differences in human and mouse |
| Q89574946 | Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis |
| Q91287173 | Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells |
| Q50187342 | Elixir of Life: Thwarting Aging With Regenerative Reprogramming |
| Q35671770 | Emerging models and paradigms for stem cell ageing |
| Q47441774 | Endothelial transplantation rejuvenates aged hematopoietic stem cell function |
| Q92570836 | Epigenetic Changes as a Target in Aging Haematopoietic Stem Cells and Age-Related Malignancies |
| Q26774949 | Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications |
| Q26745718 | Epigenetic perturbations in aging stem cells |
| Q37858414 | Epigenetic regulation of aging stem cells |
| Q33804172 | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal |
| Q38594905 | Evolution of normal and neoplastic tissue stem cells: progress after Robert Hooke |
| Q38844069 | Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging |
| Q34083743 | Functional diversity of stem and progenitor cells with B-lymphopoietic potential |
| Q38085694 | Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells |
| Q33777928 | Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion |
| Q26770001 | Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function |
| Q94469591 | Genetic and epigenetic stability of stem cells: Epigenetic modifiers modulate the fate of mesenchymal stem cells |
| Q26853420 | Genetic regulation of thymocyte progenitor aging |
| Q91468445 | Haematopoietic stem cell activity and interactions with the niche |
| Q93120640 | Hematopoietic Stem Cell Heterogeneity |
| Q39191540 | Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions |
| Q36066153 | Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias. |
| Q35647543 | Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. |
| Q84691466 | Identification and In Vivo Analysis of Murine Hematopoietic Stem Cells |
| Q38090908 | Immune cell dysfunction and inflammation in end-stage renal disease |
| Q36930979 | Immunity, ageing and cancer |
| Q26861735 | Immunosenescence and organ transplantation |
| Q34859147 | Impact of donor age on outcome after allogeneic hematopoietic cell transplantation |
| Q28308125 | Impact of genomic damage and ageing on stem cell function |
| Q38063349 | Impact of immunosenescence on transplant outcome |
| Q38552801 | Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells |
| Q21284973 | Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative Analysis |
| Q28074446 | Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment |
| Q36031591 | Inhibition of B Lymphopoiesis by Adipocytes and IL-1-Producing Myeloid-Derived Suppressor Cells |
| Q34997683 | Is normal hematopoiesis maintained solely by long-term multipotent stem cells? |
| Q38059443 | Kidney transplantation and the ageing immune system |
| Q33767453 | Kidney transplantation in the elderly |
| Q47787243 | Lifelong haematopoiesis is established by hundreds of precursors throughout mammalian ontogeny. |
| Q34699648 | Lifespan differences in hematopoietic stem cells are due to imperfect repair and unstable mean-reversion |
| Q49886620 | Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches |
| Q41381598 | Lnk deficiency partially mitigates hematopoietic stem cell aging. |
| Q35086136 | Long-term regulation of genetically modified primary hematopoietic cells in dogs |
| Q92441856 | Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation |
| Q54577779 | Loss of GADD34 induces early age-dependent deviation to the myeloid lineage. |
| Q64122246 | Lymphoid-Biased Hematopoietic Stem Cells Are Maintained with Age and Efficiently Generate Lymphoid Progeny |
| Q34825281 | Manifestations and mechanisms of stem cell aging. |
| Q98471265 | Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing |
| Q37303855 | Modeling human hematopoietic stem cell biology in the mouse |
| Q95840305 | Niche rather than origin dysregulates mucosal Langerhans cells development in aged mice |
| Q89246436 | Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing |
| Q92394724 | Plausible Links Between Metabolic Networks, Stem Cells, and Longevity |
| Q35016534 | Potential relationship between inadequate response to DNA damage and development of myelodysplastic syndrome. |
| Q34693735 | Predicting clonal self-renewal and extinction of hematopoietic stem cells |
| Q34198784 | Progeroid syndromes: models for stem cell aging? |
| Q33915908 | Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. |
| Q33849340 | Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle |
| Q27323151 | Reduced expression of MYC increases longevity and enhances healthspan |
| Q39134073 | Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules |
| Q38249102 | Regulation of hematopoietic stem cell aging by the small RhoGTPase Cdc42 |
| Q39359566 | Regulation of the hematopoietic stem cell lifecycle by the endothelial niche |
| Q36605634 | Replenishing B lymphocytes in health and disease |
| Q58793835 | Repopulating hematopoietic stem cells from steady-state blood before and after culture are enriched in the CD34CD133CXCR4 fraction |
| Q42617545 | Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies. |
| Q42762423 | Reversing B cell aging |
| Q27693905 | Rheumatoid Arthritis: A Role for Immunosenescence? |
| Q27317353 | Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion |
| Q42153021 | Self-renewal of stem cells |
| Q36765250 | Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells |
| Q33834587 | Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML. |
| Q26991467 | Sirtuins in hematological aging and malignancy |
| Q33902371 | Some hematopoietic stem cells are more equal than others |
| Q37344581 | Stem cell aging: survival of the laziest? |
| Q27026635 | Stem cell heterogeneity: implications for aging and regenerative medicine |
| Q34314546 | Stem cells and aging: a chicken-or-the-egg issue? |
| Q37774767 | Stem cells and the aging hematopoietic system |
| Q47717967 | Stem cells: Aging and transcriptional fingerprints |
| Q38265548 | T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance. |
| Q89222089 | TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells |
| Q35894071 | TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity. |
| Q37637719 | The aging immune system and its relationship to the development of chronic obstructive pulmonary disease |
| Q89865196 | The aging skin microenvironment dictates stem cell behavior |
| Q38712466 | The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging |
| Q91723487 | The global clonal complexity of the murine blood system declines throughout life and after serial transplantation |
| Q48509779 | The impact of aging on primate hematopoiesis as interrogated by clonal tracking. |
| Q28077078 | The many faces of hematopoietic stem cell heterogeneity |
| Q36455187 | The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats. |
| Q57291210 | The multifaceted role of autophagy in cancer and the microenvironment |
| Q64917514 | The potential of non-myeloablative heterochronous autologous hematopoietic stem cell transplantation for extending a healthy life span. |
| Q28243485 | Tif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cells |
| Q37429379 | Tissue resident stem cells: till death do us part |
| Q35382148 | Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding |
| Q41907198 | Transplantation Dose Alters the Differentiation Program of Hematopoietic Stem Cells |
| Q50789254 | Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation. |
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| Q26770845 | When stem cells grow old: phenotypes and mechanisms of stem cell aging |
| Q50591318 | Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways. |
| Q37615257 | Young Bone-Marrow Sca-1+ Stem Cells Rejuvenate the Aged Heart and Improve Function after Injury through PDGFRβ-Akt pathway |
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