Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis

scientific article published on January 2007

Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID2424245
P698PubMed publication ID18548129

P2093author name stringJun Zhang
Yi Lu
Andrew Lu
Binghua Jiang
Derrick Beech
P2860cites workActivation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1Q24316075
Tumor angiogenesis: therapeutic implicationsQ27860595
Deletion of p16 and p15 genes in brain tumorsQ28242452
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The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.Q33301664
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cellsQ34047111
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Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.Q40136580
Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancersQ40245632
Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models.Q40745321
RB2/p130 gene-enhanced expression down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in vivoQ40824459
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Angiogenic growth factors in preinvasive breast disease.Q41698525
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Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell linesQ43758356
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cellsQ43821708
Delivery of adenoviral vectors to the prostate for gene therapyQ45856917
In vivo expression of prostate-specific adenoviral vectors in a canine modelQ45862635
Adenoviral vector containing wild-type p16 suppresses prostate cancer growth and prolongs survival by inducing cell senescenceQ45866767
Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancerQ45887756
Green tea inhibits vascular endothelial growth factor (VEGF) induction in human breast cancer cellsQ46826131
Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas.Q48136880
Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTS1) genes in adult T-cell leukemiaQ49298452
Association of p53, p16, and vascular endothelial growth factor protein expressions with the prognosis and metastasis of gallbladder cancerQ50177638
Preferential loss of expression of p16(INK4a) rather than p19(ARF) in breast cancer.Q53448930
Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms.Q54790226
Epidemiology. Search for a killer: focus shifts from fat to hormonesQ70554011
Frequency of homozygous deletion at p16/CDKN2 in primary human tumoursQ71721193
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Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locusQ73013865
Phyllodes tumor: a clinicopathologic and immunohistochemical study of 30 casesQ79336638
Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumorQ81675946
P921main subjectcancer metastasisQ120912394
tumor angiogenesisQ110495869
P304page(s)273-286
P577publication date2007-01-01
P1433published inCancer therapyQ27721028
P1476titleSuppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis
P478volume5

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cites work (P2860)
Q89522953Combretastatin A-4 disodium phosphate and low dose gamma irradiation suppress hepatocellular carcinoma by downregulating ROCK1 and VEGF gene expression
Q33634969Development of a Novel Anti-HIF-1α Screening System Coupled with Biochemical and Biological Validation for Rapidly Selecting Potent Anti-Cancer Compounds
Q39584487EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice
Q39468057Effects of Hypoxia, Surrounding Fibroblasts, and p16 Expression on Breast Cancer Cell Migration and Invasion
Q37631817Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis
Q87466299Fenofibrate enhances radiosensitivity of esophageal squamous cell carcinoma by suppressing hypoxia-inducible factor-1α expression
Q38750852Human and Swine Dental Pulp Stem Cells Form a Vascularlike Network after Angiogenic Differentiation in Comparison with Endothelial Cells: A Quantitative Analysis
Q36393112Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes
Q36128936Inhibition of Breast Tumor Cell Growth by Ectopic Expression of p16/INK4A Via Combined Effects of Cell Cycle Arrest, Senescence and Apoptotic Induction, and Angiogenesis Inhibition
Q42105077Inhibition of Hypoxia-Induced Cell Motility by p16 in MDA-MB-231 Breast Cancer Cells
Q34919916Melittin suppresses HIF-1α/VEGF expression through inhibition of ERK and mTOR/p70S6K pathway in human cervical carcinoma cells
Q34583152Overexpression of the RNA binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis
Q30430373PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells
Q33826204PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.
Q36201751Selection, Analysis and Improvement of Anti-Angiogenesis Compounds Identified by an Anti-HIF-1α Screening and Validation System

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