Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial

scientific article published on 14 March 2013

Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1023098364
P356DOI10.1186/1745-6215-14-73
P932PMC publication ID3607855
P698PubMed publication ID23497590
P5875ResearchGate publication ID236052028

P50authorLoïc GuillevinQ88410079
Jeffrey L. WintersQ40539490
P2093author name stringMichael Walsh
Peter A Merkel
Charles D Pusey
William F Clark
Keith Wheatley
Jeffrey L Winters
Wladimir Szpirt
David Jayne
Karen Quillen
Natalie Ives
Chen Au Peh
Janak De Zoysa
PEXIVAS Investigators
P2860cites workLong-term effects of combination treatment with fludarabine and low-dose pulse cyclophosphamide in patients with lupus nephritisQ79818389
Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitisQ80507400
Chances of renal recovery for dialysis-dependent ANCA-associated glomerulonephritisQ80538509
Plasma exchange for induction and cyclosporine A for maintenance of remission in Wegener's granulomatosis--a clinical randomized controlled trialQ84473965
Risk factors for relapse of antineutrophil cytoplasmic antibody-associated vasculitisQ85001743
Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodiesQ28298876
Damage caused by Wegener's granulomatosis and its treatment: prospective data from the Wegener's Granulomatosis Etanercept Trial (WGET).Q30993164
Steroid avoidance or withdrawal after renal transplantation increases the risk of acute rejection but decreases cardiovascular risk. A meta-analysisQ33522922
Plasma exchange for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta-analysisQ34708735
Clinical research for rare disease: opportunities, challenges, and solutionsQ35100707
Rituximab versus cyclophosphamide for ANCA-associated vasculitisQ35109118
Plasmapheresis therapy for diffuse alveolar hemorrhage in patients with small-vessel vasculitisQ35600163
The contrasting epidemiology of granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitisQ36301691
Surrogate end points in clinical trials: the case of anti-neutrophil cytoplasm antibody-associated vasculitis.Q36827302
Predictors of treatment resistance and relapse in antineutrophil cytoplasmic antibody-associated small-vessel vasculitis: comparison of two independent cohortsQ37369221
A systematic review on steroid withdrawal between 3 and 6 months after kidney transplantation.Q37767354
Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndromeQ39372611
Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse eventsQ40715589
Rituximab versus cyclophosphamide in ANCA-associated renal vasculitisQ42963758
Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitisQ43740676
Dose-related inhibition of proinflammatory cytokine release from neutrophils of the newborn by dexamethasone, betamethasone, and hydrocortisoneQ44095942
Clinical and histologic determinants of renal outcome in ANCA-associated vasculitis: A prospective analysis of 100 patients with severe renal involvementQ44474550
Long-term patient survival in ANCA-associated vasculitisQ44822405
Wegener Granulomatosis: An Analysis of 158 PatientsQ45267316
Treatment for rheumatoid arthritis and the risk of hospitalization for pneumonia: associations with prednisone, disease-modifying antirheumatic drugs, and anti-tumor necrosis factor therapyQ46919825
Recovery from Goodpasture's syndrome after immunosuppressive treatment and plasmapheresisQ55192042
Methylprednisolone dosage effects on peripheral lymphocyte subpopulations and eicosanoid synthesisQ57704480
P921main subjectantibodyQ79460
cytoplasmQ79899
randomized controlled trialQ1436668
P304page(s)73
P577publication date2013-03-14
P1433published inTrialsQ7840023
P1476titlePlasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial
P478volume14

Reverse relations

cites work (P2860)
Q88851412ANCA Glomerulonephritis and Vasculitis
Q39339897ANCA-associated vasculitis with renal involvement
Q55340553Antineutrophil cytoplasmic antibody associated vasculitides with renal involvement: Open challenges in the remission induction therapy.
Q35836369Benefits of an expanded use of plasma exchange for anti-neutrophil cytoplasmic antibody-associated vasculitis within a dedicated clinical service
Q47800187Biological Agents and Therapeutic Plasma Exchange: Can They Coexist in the Future?
Q41481664Clinical Trials in Vasculitis
Q39088103Clinical trials in antineutrophil cytoplasmic antibody-associated vasculitis: what we have learnt so far, and what we still have to learn
Q50069110Con: High-volume plasma exchange application in nephrology and beyond
Q41208157Con: Should all patients with anti-neutrophil cytoplasmic antibody-associated vasculitis be primarily treated with rituximab?
Q38543360Conventional induction and maintenance treatment of Antineutrophil cytoplasmic antibodies-associated vasculitis - still of value for our patients?
Q27025692Current and future prospects in the management of granulomatosis with polyangiitis (Wegener's granulomatosis)
Q40684657EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis.
Q53513595End-stage renal disease in ANCA-associated vasculitis.
Q37640836Experience with rituximab in the treatment of antineutrophil cytoplasmic antibody associated vasculitis
Q97590549Gene variants and treatment outcomes in antineutrophil cytoplasmic antibody-associated vasculitis
Q44119588Glomerular disease: ANCA-associated GN--to PLEX or not to PLEX?
Q30276550Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue
Q93050598Hallmark trials in ANCA-associated vasculitis (AAV) for the pediatric rheumatologist
Q38709517Hurdles to the introduction of new therapies for immune-mediated kidney diseases
Q33952749Induction monotherapy with sirolimus has selected beneficial effects on glomerular and tubulointersititial injury in nephrotoxic serum nephritis
Q64250361Intravenous pulse methylprednisolone for induction of remission in severe ANCA associated Vasculitis: a multi-center retrospective cohort study
Q48937679Issues in trial design for ANCA-associated and large-vessel vasculitis
Q98735911Lactobacillus acidophilus Endocarditis Complicated by Pauci-Immune Necrotizing Glomerulonephritis
Q87829268Long-term follow-up of a combined rituximab and cyclophosphamide regimen in renal anti-neutrophil cytoplasm antibody-associated vasculitis
Q37093451Long-term outcome of patients with ANCA-associated vasculitis treated with plasma exchange: a retrospective, single-centre study
Q47191744Low-dose glucocorticoids plus rituximab versus high-dose glucocorticoids plus rituximab for remission induction in ANCA-associated vasculitis (LoVAS): protocol for a multicentre, open-label, randomised controlled trial
Q33564565Lung involvement in childhood onset granulomatosis with polyangiitis
Q38818682Management of Small Vessel Vasculitides
Q94673520Narrative Review of Hypercoagulability in Small-Vessel Vasculitis
Q39072021Paediatric anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: an update on renal management.
Q38946711Pathogenesis and treatment of ANCA-associated vasculitis-a role for complement.
Q89694411Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis
Q38377281Plasma exchange in antineutrophil cytoplasmic antibody-associated vasculitis--a 25-year perspective
Q41099072Plasmapheresis therapy in ANCA-associated vasculitides: A single-center retrospective analysis of renal outcome and mortality
Q58773547Primary Vasculitis in Childhood: GPA and MPA in Childhood
Q47741998Pro: High dose of therapeutic plasma exchange-mind the gap!
Q49679461Pyoderma Gangrenosum-associated Granulomatosis with Polyangitis: A Case Report and Literature Review
Q26751357Recent advances in anti-neutrophil cytoplasmic antibody-associated vasculitis
Q39117005Rituximab in ANCA-Associated Vasculitis
Q35228543Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement
Q38489783Role of therapeutic plasmapheresis in ANCA-associated vasculitis.
Q50076914S1 guidelines Diagnostics and treatment of ANCA-associated vasculitis
Q50086076S1 guidelines on diagnostics and treatment of ANCA-associated vasculitis
Q37647438The Effects of Plasma Exchange on Severe Vasculitis with Diffuse Alveolar Hemorrhage.
Q47107377The European Vasculitis Society 2016 Meeting Report
Q87954665The treatment of ANCA-associated rapidly-progressive glomerulonephritis and Goodpasture syndrome with therapeutic apheresis
Q59160663Therapeutic Management of Pediatric Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis
Q64260727Therapeutic Plasma Exchange in Renal Disorders
Q91991945Therapeutic plasma exchange - A brief review of indications, urgency, schedule, and technical aspects
Q53695276Therapeutic plasma exchange for refractory SLE: A comparison of outcomes between different sub-phenotypes.
Q47553136Therapeutic plasma exchange in a tertiary care center: 185 patients undergoing 912 treatments - a one-year retrospective analysis
Q38965278Therapy and prognosis of ANCA-associated vasculitis from the clinical nephrologist's perspective.
Q40867645Therapy of ANCA-associated vasculitis with severe renal manifestation under routine conditions
Q41476938Treatment of systemic necrotizing vasculitides in patients aged sixty-five years or older: results of a multicenter, open-label, randomized controlled trial of corticosteroid and cyclophosphamide-based induction therapy
Q38389839Twenty-five years of European Union collaboration in ANCA-associated vasculitis research
Q28069897Updates in ANCA-associated vasculitis
Q91962322Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis
Q39215583Variation in the Treatment of Children Hospitalized With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in the US.
Q53060772What are the Newer Applications for Therapeutic Apheresis in Nephrology?: Clinical Application of Therapeutic Apheresis in Nephrology in Japan.
Q28259540What is new in the management of rapidly progressive glomerulonephritis?
Q51733829[Role of plasmapheresis and immunoadsorption in salvage therapy of rheumatological diseases].
Q93111593[What are the indications for rescue procedures? : Systemic rheumatic diseases in the intensive care unit]