Nascent endothelium initiates Th2 polarization of asthma

scientific article published on 20 February 2013

Nascent endothelium initiates Th2 polarization of asthma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.1202095
P932PMC publication ID3608697
P698PubMed publication ID23427249
P5875ResearchGate publication ID235682815

P50authorSerpil C. ErzurumQ99561107
Kewal AsosinghQ128024264
P2093author name stringXiaoxia Li
Georgiana Cheng
Weiling Xu
Mark A Aronica
Benjamin M Savasky
P2860cites workSTAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activationQ24303982
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunityQ24630261
IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responsesQ24630608
Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeabilityQ24634777
Angiogenesis in cancer and other diseasesQ27861015
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisQ28140788
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivoQ28213431
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasisQ28264314
VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassemblyQ28298669
Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammationQ28587850
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Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cellsQ29619771
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Allergen-induced, eotaxin-rich, proangiogenic bone marrow progenitors: a blood-borne cellular envoy for lung eosinophiliaQ33774598
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.Q34132655
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severityQ34424967
T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthmaQ34533661
Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions.Q34583004
Asthma and allergic inflammationQ35099497
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammationQ35133853
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodelingQ35569863
Endothelial progenitor cells: characterization and role in vascular biologyQ35867837
Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathologyQ36044280
Maintenance and repair of the lung endothelium does not involve contributions from marrow-derived endothelial precursor cells.Q36110551
Mast cell-airway smooth muscle crosstalk: the role of thymic stromal lymphopoietin.Q36163542
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.Q36209876
Interleukin 25 promotes the initiation of proallergic type 2 responses.Q36229535
Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient miceQ36400723
Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cellsQ36402579
A role for TSLP in the development of inflammation in an asthma modelQ36403050
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cellsQ36403748
Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivoQ36435638
Redox regulation of interleukin-4 signalingQ37073431
Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature.Q40460350
Reversal of thymic stromal lymphopoietin-induced airway inflammation through inhibition of Th2 responsesQ40812554
A comparison of the antigen-presenting capabilities of class II MHC-expressing human lung epithelial and endothelial cellsQ41100605
The pathology of asthma, with special reference to changes in the bronchial mucosaQ41286069
The codependence of angiogenesis and chronic inflammationQ41508311
Preterm rabbit lung tissue mechanics: maturational changes and effect of antenatal steroidsQ43128264
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthmaQ43423039
Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeabilityQ43974009
Recall helper T cell response: T helper 1 cell-resistant allergic susceptibility without biasing uncommitted CD4 T cellsQ44655793
Comparisons of effects of intravenous and inhaled methacholine on airway physiology in a murine asthma model.Q46167988
Susceptibility to allergic lung disease regulated by recall responses of dual-receptor memory T cells.Q51996003
Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathwaysQ75303700
Th1- and Th2-dependent endothelial progenitor cell recruitment and angiogenic switch in asthmaQ80257407
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesisQ81277909
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectasthmaQ35869
endotheliumQ111140
P304page(s)3458-3465
P577publication date2013-02-20
P1433published inJournal of ImmunologyQ3521441
P1476titleNascent endothelium initiates Th2 polarization of asthma
P478volume190

Reverse relations

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