Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus

scientific article published on 22 March 2016

Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037184727
P356DOI10.1186/S12933-016-0362-0
P932PMC publication ID4804508
P698PubMed publication ID27005817
P5875ResearchGate publication ID299380792

P2093author name stringDan Liu
Yaling Han
Xiaolin Zhang
Tengfei Liu
Chenghui Yan
Wenzhi Cai
Dingyu Zhang
P2860cites workPlatelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatmentQ28185431
Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatmentQ28199546
Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?Q28218910
Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectivesQ28222158
Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery diseaseQ28222643
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultationQ29547453
Ticagrelor versus clopidogrel in patients with acute coronary syndromesQ29619002
High platelet reactivity on clopidogrel therapy correlates with increased coronary atherosclerosis and calcification: a volumetric intravascular ultrasound studyQ30450312
Tag SNP selection in genotype data for maximizing SNP prediction accuracyQ30992243
GEVALT: an integrated software tool for genotype analysisQ33271462
Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stentsQ33335010
A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 TrialQ34751965
Genetic determinants of response to clopidogrel and cardiovascular eventsQ34910210
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort studyQ34910745
The effect of clopidogrel on platelet activity in patients with and without type-2 diabetes mellitus: a comparative studyQ35073622
Insulin receptor substrate 1 (IRS1) variants confer risk of diabetes in the Boston Puerto Rican Health StudyQ35598032
Low fasting glucose is associated with enhanced thrombin generation and unfavorable fibrin clot properties in type 2 diabetic patients with high cardiovascular riskQ35609789
Diabetes mellitus and platelet reactivity in patients under prasugrel or ticagrelor treatment: an observational studyQ35677083
Platelet function monitoring in patients with coronary artery diseaseQ36990868
microRNAs and cancer: an overviewQ37249283
Antiplatelet therapy in diabetes: efficacy and limitations of current treatment strategies and future directionsQ37428365
Diabetes mellitus and acute coronary syndrome: lessons from randomized clinical trialsQ38005018
Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetesQ38430548
Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulinQ40693554
Effect of an optimized treatment with insulin on platelet reactivity after discharge in patients with an acute coronary syndrome and hyperglycemiaQ43981677
Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention TrialQ44459441
IRS-1 Mediates Inhibition of Ca2+ Mobilization by Insulin via the Inhibitory G-protein GiQ44645484
Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham StudyQ44680472
A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study.Q46528728
A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosisQ46811912
Platelet inhibition by insulin is absent in type 2 diabetes mellitusQ46843983
Prasugrel versus clopidogrel in patients with acute coronary syndromesQ46915044
Comparison of therapy with Ticagrelor, Prasugrel or high Clopidogrel dose in PCI patients with high on treatment platelet reactivity and genotype variation. TRIPLETE RESET trial.Q51628204
Impact of Insulin Receptor Substrate-1 Genotypes on Platelet Reactivity and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Coronary Artery DiseaseQ57764490
Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) studyQ79685552
Impact of CYP2C19 polymorphism on residual platelet reactivity in patients with coronary heart disease during antiplatelet therapyQ82942386
Pharmacogenetics in cardiovascular antithrombotic therapyQ84541445
Impact of diabetes mellitus on vessel response in the drug-eluting stent era: pooled volumetric intravascular ultrasound analysesQ85426083
Impact of CYP2C19 polymorphism on clinical outcome following coronary stenting is more important in non-diabetic than diabetic patientsQ87861118
P407language of work or nameEnglishQ1860
P921main subjectcoronary artery diseaseQ844935
type 2 diabetesQ3025883
clopidogrelQ410237
P304page(s)50
P577publication date2016-03-22
P1433published inCardiovascular DiabetologyQ2468083
P1476titleAssociation between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus
P478volume15

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cites work (P2860)
Q49908173Comparison of pharmacodynamic effects of ticagrelor vs prasugrel in type 2 diabetes mellitus patients with coronary heart disease
Q38924963IRS proteins and diabetic complications
Q58795845Impaired glucose metabolism is associated with increased thrombin generation potential in patients undergoing angioplasty and stenting
Q42254531PRotective Effect on the coronary microcirculation of patients with DIabetes by Clopidogrel or Ticagrelor (PREDICT): study rationale and design. A randomized multicenter clinical trial using intracoronary multimodal physiology
Q55471692Pharmacogenetic association study on clopidogrel response in Puerto Rican Hispanics with cardiovascular disease: a novel characterization of a Caribbean population.
Q37724614Pharmacokinetic and Pharmacodynamic Responses to Clopidogrel: Evidences and Perspectives
Q39343342Platelets, diabetes and myocardial ischemia/reperfusion injury.
Q33818356Potential Usefulness of Clopidogrel Pharmacogenetics in Cerebral Endovascular Procedures and Carotid Artery Stenting.
Q57279877The role of insulin receptor substrate 1 gene polymorphism Gly972Arg as a risk factor for ischemic stroke among Indonesian subjects

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