Transcriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex

scientific article published on September 1990

Transcriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.10.9.4978
P932PMC publication ID361127
P698PubMed publication ID2117705

P50authorFrancis W. RuscettiQ111337552
P2093author name stringA B Roberts
S J Kim
R Friedman
A Geiser
M B Sporn
J Kasper
H D Lee
M C Birchenall-Roberts
P2860cites workActivation of the pp60c-src protein kinase is an early event in colonic carcinogenesisQ24559903
Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseQ26778460
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1Q28291340
Stimulatory role of transforming growth factors in multistage skin carcinogenesis: possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skinQ36009391
Characterization of the promoter region of the human transforming growth factor-beta 1 geneQ36416766
Transforming growth factor-beta: possible roles in carcinogenesisQ36465897
Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complexQ36755274
Gene regulation by tyrosine kinases: src protein activates various promoters, including c-fosQ36757337
Type beta transforming growth factor: a bifunctional regulator of cellular growthQ37672515
Serum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylationQ37672941
Introduction of v-abl oncogene induces monocytic differentiation of an IL-3-dependent myeloid progenitor cell lineQ41738935
The antiproliferative effect of type beta transforming growth factor occurs at a level distal from receptors for growth-activating factorsQ42503775
Prolonged activation of jun and collagenase genes by tumour necrosis factor-alphaQ43819767
Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5' element and c-fos 3' sequencesQ48375058
Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.Q53521743
Lectins modulate the internalization of recombinant interferon-alpha A and the induction of 2',5'-oligo(A) synthetase.Q53522215
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factorsQ58485006
TGF-beta inhibits growth factor-induced DNA synthesis in hamster fibroblasts without affecting the early mitogenic eventsQ67920501
Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinductionQ69588815
Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1Q69763276
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)4978-4983
P577publication date1990-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleTranscriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex
P478volume10

Reverse relations

cites work (P2860)
Q36674584A Signaling Network Controlling Androgenic Repression of c-Fos Protein in Prostate Adenocarcinoma Cells
Q47767276Activation of mitogen-activated protein kinases and activator protein-1 in myocardial infarction in rats
Q34136521Angiogenesis in breast cancer: the role of transforming growth factor beta and CD105.
Q47107875Blockade of Eosinophil-Induced Bronchial Epithelial-Mesenchymal Transition with a Geranyl Acetophenone in a Coculture Model
Q55449361Butyrate produced by gut commensal bacteria activates TGF-beta1 expression through the transcription factor SP1 in human intestinal epithelial cells.
Q36679595Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-ras oncogene
Q30168628Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently
Q42458805Computational identification of potential transcriptional regulators of TGF-ß1 in human atherosclerotic arteries.
Q28389110Conditional radioresistance of Tet-inducible manganese superoxide dismutase bone marrow stromal cell lines
Q41676045Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells
Q30450251Differential Modulation of Plasminogen Activator Gene Expression by Oncogene-Encoded Protein Tyrosine Kinases
Q36620077Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development
Q28075996Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity
Q54127845Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.
Q35119392Genealogy, expression, and cellular function of transforming growth factor-β
Q92205468HIV-1 proteins gp120 and tat induce the epithelial-mesenchymal transition in oral and genital mucosal epithelial cells
Q41100541How tumors become angiogenic
Q99627697Human immunodeficiency virus interaction with oral and genital mucosal epithelia may lead to epithelial-mesenchymal transition and sequestration of virions in the endosomal compartments
Q36869420Identification of Essentialcis-Acting Regulatory Elements for Transcription of the RatDANGene
Q40163864Induction of transforming growth factor-beta1 by basic fibroblast growth factor in rat C6 glioma cells and astrocytes is mediated by MEK/ERK signaling and AP-1 activation
Q83584702Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway
Q38760746JunD Is Required for Proliferation of Prostate Cancer Cells and Plays a Role in Transforming Growth Factor-β (TGF-β)-induced Inhibition of Cell Proliferation
Q40324906LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression
Q36693106Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis
Q42528758Mechanism of E1A-induced transforming growth factor-beta (TGF-beta) resistance in mouse keratinocytes involves repression of TGF-beta type II receptor transcription
Q73481965Modulation of TGF‐β1 production from human keratinocytes by UVB
Q33735927Notch signaling activation suppresses v-Src-induced transformation of neural cells by restoring TGF-β-mediated differentiation
Q36555754Nuclear localization of v-Abl leads to complex formation with cyclic AMP response element (CRE)-binding protein and transactivation through CRE motifs
Q37020157Osteopontin: regulation in tumor metastasis
Q38850479Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironment
Q40655703Regulation of the junB gene by v-src
Q34598615Retracted: Activation of TGF-β1 Promoter by Hepatitis C Virus-Induced AP-1 and Sp1: Role of TGF-β1 in Hepatic Stellate Cell Activation and Invasion
Q41168202Stimulation of mouse osteopontin promoter by v-Src is mediated by a CCAAT box-binding factor
Q40792736Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects
Q34180754Stretch augments TGF-beta1 expression through RhoA/ROCK1/2, PTK, and PI3K in airway smooth muscle cells
Q32099220Suppression of v-src transformation by the drs gene
Q34136526TGF-beta and colorectal carcinogenesis
Q97867213TGFβ biology in cancer progression and immunotherapy
Q35870737The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site
Q35097640The expression of HIV-1 Vpu in monocytes causes increased secretion of TGF-β that activates profibrogenic genes in hepatic stellate cells
Q40883612The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.
Q52181478Tissue-specific and developmental regulation of transforming growth factor-beta1 expression in fetal lamb ductus arteriosus endothelial cells.
Q34619680Transcription factor activation in response to cutaneous injury: role of AP-1 in reepithelialization
Q40678426Transcriptional activation of the CEF-4/9E3 cytokine gene by pp60v-src
Q36557011Transcriptional down regulation of the nov proto-oncogene in fibroblasts transformed by p60v-src
Q36685904Transcriptional downregulation of the retina-specific QR1 gene by pp60v-src and identification of a novel v-src-responsive unit
Q36555302Transcriptional stimulation of the retina-specific QR1 gene upon growth arrest involves a Maf-related protein
Q54104994Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2.
Q53454356Transforming Growth Factor-beta Receptors: Role in Physiology and Disease.
Q35236513Transforming growth factor beta and interleukin-1: a paradigm for opposing regulation of haemopoiesis
Q38132176Transforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer
Q34438032Transforming growth factor-beta signal transduction in epithelial cells.
Q40897760Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA.
Q41212993Transforming growth factor-beta1 modulates p107 function in myeloid cells: correlation with cell cycle progression
Q40535943V-src-induced-transcription of the avian clusterin gene
Q33854336pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-
Q42515747v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex
Q43707192v-src activation of the collagenase-1 (matrix metalloproteinase-1) promoter through PEA3 and STAT: requirement of extracellular signal-regulated kinases and inhibition by retinoic acid receptors
Q36666887v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element

Search more.