Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes

scientific article published on July 1991

Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.11.7.3711
P932PMC publication ID361136
P698PubMed publication ID1646393
P5875ResearchGate publication ID21510128

P2093author name stringS J Wilson
J C Boyer
L L Estabrooks
W K Kaufmann
P2860cites workCheckpoints: controls that ensure the order of cell cycle eventsQ28131705
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DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replicationQ36258619
Radiosensitivity in ataxia-telangiectasia: a new explanationQ36419108
New data on clonal anomalies of chromosome 14 in ataxia telangiectasia: tct(14;14) and inv(14).Q36492229
Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replicationQ36901211
In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fractionQ37691913
Inhibition and recovery of DNA synthesis in human cells after exposure to ultraviolet lightQ38521196
Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after x-irradiationQ38524035
Effect of caffeine on DNA synthesis in irradiated and unirradiated mammalian cellsQ38524424
Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cellsQ38526532
Pathways of human cell post-replication repairQ38596913
DNA topoisomerases as targets for chemotherapyQ39211064
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Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells.Q42803837
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Molecular analysis of a t(7;14)(q35;q32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasiaQ44450500
Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts.Q47255834
Studies on camptothecin. I. Effects of nucleic acid and protein synthesisQ47727975
Effect of cell proliferation and chromatin conformation on intercalator-induced, protein-associated DNA cleavage in human brain tumor cells and human fibroblastsQ48254621
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Predominant role for DNA damage in etoposide-induced cytotoxicity and cell cycle perturbation in human SV40-transformed fibroblasts.Q53533964
The role of DNA topoisomerases in recombination and genome stability: a double-edged sword?Q54710073
Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNAQ59078548
Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cellsQ64390367
Defective postreplication repair in xeroderma pigmentosum variant fibroblastsQ67285583
The action of caffeine on X-irradiated HeLa cells. I. Delayed inhibition of DNA synthesisQ67663090
Hypersensitivity of cultured ataxia-telangiectasia cells to etoposideQ68963925
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecinQ69354693
Enhanced expression of X-ray- and UV-induced chromosome aberrations by cytosine arabinoside in ataxia telangiectasia cellsQ69991471
Mechanisms of chromosomal aberration production. I. Aberration induction by ultraviolet lightQ70008573
Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblastsQ70053984
DNA topoisomerasesQ70095180
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase IQ70106083
Absence of swiveling at sites of intercalator-induced protein-associated deoxyribonucleic acid strand breaks in mammalian cell nucleoidsQ70814818
Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblastsQ71009312
Mitotic delay and repair in human lymphocytesQ71048640
DNA-repair deficiencies do not affect intercalator-induced cytotoxicity or DNA scission in human cellsQ71861168
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase IIQ72397901
Cytogenetic effects of amsacrine on human lymphocytes in vivo and in vitroQ72738296
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)3711-3718
P577publication date1991-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes
P478volume11

Reverse relations

cites work (P2860)
Q39242603Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor
Q40442271Cell cycle checkpoints and DNA repair preserve the stability of the human genome
Q40580197Cellular radiosensitivity in ataxia-telangiectasia
Q30442180Chromosome architecture can dictate site-specific initiation of DNA replication in Xenopus egg extracts
Q71953379Colcemid alters S phase and other parameters in skin during chronic exposure to benzo(a)pyrene
Q34249547Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes
Q24792540DNA and the chromosome - varied targets for chemotherapy
Q64389076DNA signals for G2 checkpoint response in diploid human fibroblasts
Q36647845DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways
Q41078479DNA topoisomerase II mutations and resistance to anti-tumor drugs
Q41137233Damage-sensing mechanisms in human cells after ionizing radiation
Q42054523Functional interactions of DNA topoisomerases with a human replication origin
Q41144438Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?
Q36559209Human chromosome 3 mediates growth arrest and suppression of apoptosis in microcell hybrids.
Q28214430Regulation of cellular and SV40 virus origins of replication by Chk1-dependent intrinsic and UVC radiation-induced checkpoints
Q36797925Regulation of the cell cycle following DNA damage in normal and Ataxia telangiectasia cells
Q28534955Role of minor groove width and hydration pattern on amsacrine interaction with DNA
Q33500497The bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitor
Q35950241The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses
Q34061976Topoisomerase I-mediated DNA damage
Q73784013Topoisomerase II cleavable complex formation within DNA loop domains
Q28378884Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I
Q40852912UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35.
Q37152060Wild-type p53 is a cell cycle checkpoint determinant following irradiation
Q41715281p53--an acrobat in tumorigenesis

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