Review: Epigenetic mechanisms in ocular disease

scientific article published on 21 March 2013

Review: Epigenetic mechanisms in ocular disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P932PMC publication ID3611946
P698PubMed publication ID23559860

P2093author name stringXiaohua Li
David R Hinton
Shikun He
Nymph Chan
P2860cites workApolipoprotein J inhibits the migration and adhesion of endothelial cells.Q50504280
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Epigenetics and cardiovascular diseaseQ85768193
MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cellsQ21135545
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brainQ22065852
An integrated encyclopedia of DNA elements in the human genomeQ22122150
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1Q24316558
Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanomaQ24606279
The role of epigenetics in the pathology of diabetic complicationsQ24609124
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineQ24614582
MicroRNAs regulate ocular neovascularizationQ24631030
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNAQ24632387
Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathwayQ24634357
Mechanisms of age-related macular degenerationQ27000182
MicroRNA-target interactions: new insights from genome-wide approachesQ27000642
Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activityQ28274440
Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activityQ28506707
Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleationQ28588453
Functions of DNA methylation: islands, start sites, gene bodies and beyondQ29547260
Cancer epigenetics: from mechanism to therapyQ29614799
Epigenetic modifications and human diseaseQ29619753
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genesQ33347134
Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosisQ33588162
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosisQ33643242
Epigenetic regulation of latent HSV-1 gene expressionQ33729340
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndromeQ33741025
DNA methylation is associated with altered gene expression in AMD.Q33939754
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genesQ33941116
Inhibition of histone deacetylase protects the retina from ischemic injuryQ33994208
Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenonQ34009114
Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cellsQ34194436
Epigenomics reveals a functional genome anatomy and a new approach to common diseaseQ34207844
Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.Q34221312
Histone deacetylase: a potential therapeutic target for fibrotic disordersQ34257607
Epigenetic regulation of the immune system in health and diseaseQ37807995
Epigenetic mechanisms in inflammationQ37823067
Role of xenobiotic metabolism in cancer: involvement of transcriptional and miRNA regulation of P450sQ37823851
Inflammatory memories: is epigenetics the missing link to persistent stromal cell activation in rheumatoid arthritis?Q37865848
Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugsQ37878207
Epigenetics: new questions on the response to hypoxiaQ37918376
An epigenetic approach toward understanding ocular α-herpesvirus pathogenesis and treatment.Q37928331
Small RNAs have a large impact: circulating microRNAs as biomarkers for human diseasesQ38018832
MicroRNAs in cancers and neurodegenerative disordersQ38051332
Long noncoding RNAs in cardiac development and pathophysiologyQ38056111
Epigenetic inactivation of RASSF1a in uveal melanoma.Q38434326
The role of RASSF1A in uveal melanomaQ39373975
A novel retinoblastoma therapy from genomic and epigenetic analysesQ39413689
Status of RASSF1A in uveal melanocytes and melanoma cells.Q39501081
MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic ratsQ39557657
Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulationQ39738064
Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse modelQ40132971
Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosaQ40150974
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cellsQ40251101
The inhibition of angiogenesis by antisense oligonucleotides to clusterinQ40347656
A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retinaQ41853631
Selective transcription and cellular proliferation induced by PDGF require histone deacetylase activityQ42804078
Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivationQ43021329
Methylation status of RASSF1A and DAPK promoter in retinoblastomaQ43231036
Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cellsQ43244783
Altered microRNA expression profiles in retinas with diabetic retinopathyQ43894251
Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell linesQ44453093
Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.Q45921402
Emerging roles of non-coding RNAs in brain evolution, development, plasticity and diseaseQ34289150
Histone deacetylases and cancer.Q34298745
Histone deacetylase inhibitors induce reactivation of herpes simplex virus type 1 in a latency-associated transcript-independent manner in neuronal cellsQ34338452
Regulated nucleosome mobility and the histone code.Q34364723
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.Q34488424
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.Q34545446
A twin approach to unraveling epigeneticsQ34713637
MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathyQ34718910
DICER1 deficit induces Alu RNA toxicity in age-related macular degenerationQ34796058
Cataracts associated with systemic disorders and syndromesQ35004228
Dark matters in AMD genetics: epigenetics and stochasticityQ35005822
MicroRNA-mediated posttranscriptional regulation is required for maintaining undifferentiated properties of blastoderm and primordial germ cells in chickensQ35081691
Therapeutic challenges to retinitis pigmentosa: from neuroprotection to gene therapy.Q35092187
Zebularine suppresses TGF-beta-induced lens epithelial cell-myofibroblast transdifferentiation by inhibiting MeCP2.Q35531772
SirT1--a sensor for monitoring self-renewal and aging process in retinal stem cells.Q35638950
Advances in epigenetics and epigenomics for neurodegenerative diseasesQ35709124
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patientsQ35874941
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retinaQ35886487
Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)Q35887465
A unique regulatory phase of DNA methylation in the early mammalian embryoQ35903352
Basic concepts of epigenetics: impact of environmental signals on gene expressionQ35911124
The genetic and epigenetic journey of embryonic stem cells into mature neural cells.Q35969352
Experimental murine myopia induces collagen type Iα1 (COL1A1) DNA methylation and altered COL1A1 messenger RNA expression in sclera.Q36015813
SNP rs1533428 at 2p16.3 as a marker for late-onset primary open-angle glaucoma.Q36073878
Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial geneticsQ36405448
Hypomethylation of the IL17RC promoter associates with age-related macular degenerationQ36442673
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.Q36693824
Epigenetics in inflammatory rheumatic diseasesQ36985127
Histone modifications and chromatin remodeling during bacterial infectionsQ37240625
Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesisQ37310665
Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiationQ37468782
Regulatory role of HIF-1alpha in the pathogenesis of age-related macular degeneration (AMD).Q37546290
Epigenetics and gene expressionQ37749500
Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transportersQ37791990
Epigenetic regulation of aging.Q37793425
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectregulation of gene expressionQ411391
eye diseaseQ3041498
genetic epigenesisQ64443099
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)665-674
P577publication date2013-03-21
P1433published inMolecular VisionQ6895981
P1476titleReview: Epigenetic mechanisms in ocular disease
P478volume19

Reverse relations

cites work (P2860)
Q33784315Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration
Q35679227An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina
Q89767028Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression
Q41717727DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders
Q35017752Diabetes and retinal vascular dysfunction
Q37280210Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
Q38244141Epigenetic modifications and potential new treatment targets in diabetic retinopathy
Q64109825Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia
Q39140153Epigenetics and Signaling Pathways in Glaucoma
Q48097604Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury
Q36129769Histone Deacetylase Inhibition Restores Retinal Pigment Epithelium Function in Hyperglycemia
Q64052110Identification of altered microRNAs in retinas of mice with oxygen-induced retinopathy
Q37612377Instability in X chromosome inactivation patterns in AMD: a new risk factor?
Q38173896Mechanism of inflammation in age-related macular degeneration: an up-to-date on genetic landmarks.
Q38170901Mobilizing endogenous stem cells for retinal repair
Q93184233Modulating Ocular Scarring in Glaucoma Filtration Surgery Using the Epigenetic Adjunct Suberoylanilide Hydroxamic Acid
Q35577823Molecular mechanisms of subretinal fibrosis in age-related macular degeneration.
Q89687599Polypoidal Choroidal Vasculopathy in Congolese Patients
Q34411723Resveratrol based oral nutritional supplement produces long-term beneficial effects on structure and visual function in human patients
Q38963936Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine
Q38252350The role of epigenetics in age-related macular degeneration
Q28393006Thioredoxin Interacting Protein (TXNIP) and Pathogenesis of Diabetic Retinopathy
Q91717473Tumour Expression of Histone Deacetylases in Uveal Melanoma

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