Inhibition of endotoxin-induced hepatotoxicity by melatonin in rats

scientific article published on June 2008

Inhibition of endotoxin-induced hepatotoxicity by melatonin in rats is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID3614694
P698PubMed publication ID23675075

P2093author name stringKanwaljit Chopra
Praveen Rishi
Sushma Bharrhan
Ashwani Koul
Manmeet Pal Singh Bhalla
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Nitric oxide: physiology, pathophysiology, and pharmacologyQ26778243
Mechanisms of hepatotoxicityQ28216749
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Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharideQ33205953
Actions of melatonin in the reduction of oxidative stress. A reviewQ34074485
Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesisQ34335212
Antibiotic-induced release of endotoxin: a reappraisalQ35535602
Regulation of antioxidant enzymes: a significant role for melatoninQ35607606
Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humansQ35636677
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progressionQ36368539
Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidenceQ36582757
Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutaseQ39184357
Multiple system organ failureQ40150241
Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions.Q40281050
Protection of lethal toxicity of endotoxin by Salvia miltiorrhiza BUNGE is via reduction in tumor necrosis factor alpha release and liver injuryQ40302774
Pathophysiology of septic shock and implications for therapy.Q40710793
Neutrophil depletion protects against liver injury from bacterial endotoxinQ41112827
Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation.Q41575182
Mechanisms of lipid peroxide formation in animal tissuesQ42588469
Melatonin prevents endotoxin-induced circulatory failure in ratsQ43584548
N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.Q43711897
Endotoxemia in human septic shockQ44348668
Influence of pro-inflammatory (IL-1 alpha, IL-6, TNF-alpha, IFN-gamma) and anti-inflammatory (IL-4) cytokines on chondrocyte functionQ44572438
Melatonin protects against pro‐oxidant enzymes and reduces lipid peroxidation in distinct membranes induced by the hydroxyl and ascorbyl radicals and by peroxynitriteQ44604274
Melatonin protects against oxidative organ injury in a rat model of sepsis.Q45204404
Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metaboliteQ47865379
Melatonin increases gene expression for antioxidant enzymes in rat brain cortexQ48506270
NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged ratsQ48566117
Melatonin attenuates lipopolysaccharide (LPS)-induced apoptotic liver damage in D-galactosamine-sensitized mice.Q51748095
Lipopolysaccharide-induced hepatotoxicity is inhibited by the antioxidant melatonin.Q54598527
Intra- and intermolecular cross-linking of membrane proteins in intact erythrocytes and ghosts by SH-oxidizing agentsQ67673484
Characterization of hepatic nitric oxide synthase: identification as the cytokine-inducible form primarily regulated by oxidantsQ71239613
Gadolinium chloride inhibits Kupffer cell nitric oxide synthase (iNOS) inductionQ71669092
Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in ratsQ78176418
[Melatonin as a corrector of free radical oxidation processes during toxic damage of liver in rat]Q80083839
P433issue2
P921main subjectendotoxinsQ319997
hepatotoxicityQ1349821
P304page(s)103-112
P577publication date2008-06-01
P1433published inInternational Journal of Biomedical ScienceQ26842285
P1476titleInhibition of endotoxin-induced hepatotoxicity by melatonin in rats
P478volume4

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