Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk

scientific article published on 25 February 2013

Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1055-9965.EPI-12-1248
P932PMC publication ID3616836
P698PubMed publication ID23441100

P50authorMark LathropQ6768494
John P KempQ30348320
Richard M MartinQ52574555
Carolina BonillaQ55174109
Jenny L DonovanQ58658676
Freddie HamdyQ67482650
David M. EvansQ30348322
Nicholas J. TimpsonQ30348324
Sarah J LewisQ37613585
David E. NealQ42941105
P2093author name stringWilliam D Fraser
Rebecca Gilbert
Smith George Davey
P2860cites work‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*Q22066036
Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylaseQ24562083
Lactase persistence-related genetic variant: population substructure and health outcomesQ24601219
Common genetic determinants of vitamin D insufficiency: a genome-wide association studyQ24602058
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypesQ24635938
Low wintertime vitamin D levels in a sample of healthy young adults of diverse ancestry living in the Toronto area: associations with vitamin D intake and skin pigmentationQ24646037
Principal components analysis corrects for stratification in genome-wide association studiesQ27860975
Metabolism of vitamin D3 by cytochromes P450Q28296000
Prostate cancer risk: associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypesQ28364894
Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin DQ28729831
Genome-wide association studies of pigmentation and skin cancer: a review and meta-analysisQ28744574
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiologyQ57108274
Unreliability of Self-reported Burning Tendency and Tanning AbilityQ68387616
Exposure to ultraviolet radiation: association with susceptibility and age at presentation with prostate cancerQ74446416
Pigmentation and vitamin D metabolism in Caucasians: low vitamin D serum levels in fair skin types in the UKQ30871474
Life course sun exposure and risk of prostate cancer: population-based nested case-control study and meta-analysis.Q33864647
Genome-wide association study of circulating vitamin D levelsQ33904451
Associations of circulating 25-hydroxyvitamin D with prostate cancer diagnosis, stage and gradeQ34228158
Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancerQ34426763
The validity and practicality of sun-reactive skin types I through VI.Q34687744
Vitamin D level in summer and winter related to measured UVR exposure and behaviorQ34999632
Vitamin d, sunlight and prostate cancer riskQ35207472
International variationQ35868021
Does sunlight have a beneficial influence on certain cancers?Q36440653
Considering the potential benefits as well as adverse effects of sun exposure: can all the potential benefits be provided by oral vitamin D supplementation?Q36449910
Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?Q37014218
Environmental exposures and prostate cancerQ37990121
Ultraviolet radiation: effects on risks of prostate cancer and other internal cancers.Q38514921
Human skin pigmentation, migration and disease susceptibilityQ39097638
The New American Joint Committee on Cancer and International Union Against Cancer TNM classification of prostate cancer. Clinicopathologic correlationsQ39370194
Outcome in prostate cancer associations with skin type and polymorphism in pigmentation-related genesQ43726273
Association of 25-hydroxyvitamin D3)levels in adult New Zealanders with ethnicity, skin color and self-reported skin sensitivity to sun exposureQ43817586
Susceptibility to prostate cancer: studies on interactions between UVR exposure and skin typeQ47938233
Prostate cancer risk and exposure to ultraviolet radiation: further support for the protective effect of sunlightQ48001820
Does a high UV environment ensure adequate vitamin D status?Q50463610
Association between quantitative measures of skin color and plasma 25-hydroxyvitamin DQ50638765
Measurement of plasma 1,25 dihydroxyvitamin D using a novel immunoextraction technique and immunoassay with iodine labelled vitamin D tracer.Q52253508
P433issue4
P921main subjectvitamin DQ175621
prostate cancerQ181257
exposure assessmentQ4008388
causal relationshipQ130278256
P304page(s)597-606
P577publication date2013-02-25
P1433published inCancer Epidemiology, Biomarkers & PreventionQ326334
P1476titleUsing genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk
P478volume22

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cites work (P2860)
Q38676502Adding Mendelian randomization to a meta-analysis-a burgeoning opportunity
Q51764870Associations between sun sensitive pigmentary genes and serum prostate specific antigen levels.
Q34983624Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case-control study
Q58752317Correlating blood-based DNA methylation markers and prostate cancer risk in African-American men
Q45777210Identification of low oxygen-tolerating bacteria in prostate secretions of cancer patients and discussion of possible aetiological significance.
Q35796865Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy
Q64958736Mendelian randomization studies of cancer risk: a literature review.
Q26999349Mendelian randomization studies: a review of the approaches used and the quality of reporting
Q64971077PAX3 is a biomarker and prognostic factor in melanoma: Database mining.
Q92718647PCaLiStDB: a lifestyle database for precision prevention of prostate cancer
Q58783378Pigmentation phototype and prostate and breast cancer in a select Spanish population-A Mendelian randomization analysis in the MCC-Spain study
Q33992469Polymorphisms in vitamin D-related genes and risk of uterine leiomyomata.
Q33792547Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children
Q48188531Whither the genotype-phenotype relationship? An historical and methodological appraisal.

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