A functional genomics screen for microRNA regulators of NF-kappaB signaling

scientific article published on 28 February 2013

A functional genomics screen for microRNA regulators of NF-kappaB signaling is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1006041788
P356DOI10.1186/1741-7007-11-19
P932PMC publication ID3621838
P698PubMed publication ID23448136
P5875ResearchGate publication ID235754996

P2093author name stringJohn B Hogenesch
Michal A Elovitz
Lauren Anton
Yih-Chii Hwang
Anthony O Olarerin-George
P2860cites workPrinciples of microRNA-target recognitionQ21146368
Multiple nuclear factors interact with the immunoglobulin enhancer sequencesQ24296245
ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaBQ24336707
MicroRNA targeting specificity in mammals: determinants beyond seed pairingQ24607724
miRBase: integrating microRNA annotation and deep-sequencing dataQ24615914
Genomic screening with RNAi: results and challengesQ24626537
MicroRNAs in NF-kappaB signalingQ24630097
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIPQ24630900
MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517aQ36924035
Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the diseaseQ37295740
What have RNAi screens taught us about viral-host interactions?Q37540874
microRNA: a master regulator of cellular processes for bioengineering systemsQ37736481
Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.Q38330353
MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.Q39430328
Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell linesQ39561328
Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cellsQ39773001
Rel/NF-kappa B and I kappa B proteins: an overviewQ41595423
Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumorsQ41817349
microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophagesQ47781337
Underexpression of 4 placenta-associated microRNAs in complete hydatidiform molesQ84309104
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAsQ24635151
Argonaute HITS-CLIP decodes microRNA-mRNA interaction mapsQ24645826
ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic developmentQ24653526
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesQ24670080
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammalsQ24680274
The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABINQ24682087
Mammalian microRNAs predominantly act to decrease target mRNA levelsQ27860535
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsQ27861053
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosisQ28190313
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
Identification of hundreds of conserved and nonconserved human microRNAsQ28257480
Introduction to NF-kappaB: players, pathways, perspectivesQ28271022
NF-kappaB and the immune responseQ28271031
Specificity of microRNA target selection in translational repressionQ28776123
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21Q28975612
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolutionQ29616370
Suppression of TNF-alpha-induced apoptosis by NF-kappaBQ29618717
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shockQ29619768
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanismQ29619866
A functional map of NFkappaB signaling identifies novel modulators and multiple system controlsQ30482040
NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responsesQ30972954
Human villous trophoblasts express and secrete placenta-specific microRNAs into maternal circulation via exosomesQ33459716
Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cellsQ33889371
STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to CancerQ34088885
Genetic variation in microRNA networks: the implications for cancer researchQ34177121
miR-301a as an NF-κB activator in pancreatic cancer cellsQ34485753
Mutations in the NF-kappaB signaling pathway: implications for human diseaseQ34577553
MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loopQ35640588
MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)Q35974211
MicroRNA-181b regulates NF-κB-mediated vascular inflammationQ36005391
IkappaB kinase complexes: gateways to NF-kappaB activation and transcriptionQ36637874
Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.Q36637897
P921main subjectgenomicsQ222046
microRNAQ310899
NF-κBQ411114
functional genomicsQ1068690
P304page(s)19
P577publication date2013-02-28
P1433published inBMC BiologyQ2545642
P1476titleA functional genomics screen for microRNA regulators of NF-kappaB signaling
P478volume11

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