Preventive Effect of Geraniol on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats

scientific article published on March 2016

Preventive Effect of Geraniol on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4816747
P698PubMed publication ID27046949

P2093author name stringRyo Abe
Hajime Isomoto
Jun-Ichi Okano
Yoshikazu Murawaki
Ryu Imamoto
Shintaro Sawada
Masahiko Koda
Yuki Yasunaka
P2860cites workN-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiationQ28296366
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Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 SignalingQ28546382
Hepatocellular carcinoma pathogenesis: from genes to environmentQ29615767
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Regulation of glutathione transferase P: a tumor marker of hepatocarcinogenesisQ36791976
Development of evidence-based clinical guidelines for the diagnosis and treatment of hepatocellular carcinoma in JapanQ37014868
Chemoprevention against hepatocellular carcinomaQ38550165
Suppression by geraniol of the growth of A549 human lung adenocarcinoma cells and inhibition of the mevalonate pathway in culture and in vivo: potential use in cancer chemotherapyQ38990351
Inhibitory effect of geraniol in combination with gemcitabine on proliferation of BXPC-3 human pancreatic cancer cellsQ39134968
Transcriptional and posttranscriptional inhibition of HMGCR and PC biosynthesis by geraniol in 2 Hep-G2 cell proliferation linked pathwaysQ39152808
Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell lineQ39511345
Sequential analysis of diethylnitrosamine-induced hepatocarcinogenesis in ratsQ39554423
Total numbers of undiagnosed carriers of hepatitis C and B viruses in Japan estimated by age- and area-specific prevalence on the national scale.Q39765312
Null anticarcinogenic effect of silymarin on diethylnitrosamine-induced hepatocarcinogenesis in ratsQ41918847
Validation and limitation of age-period-cohort model in simulating mortality due to hepatocellular carcinoma from 1940 to 2010 in JapanQ42260526
Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathwaysQ42726926
Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced ratsQ44812837
Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenograftsQ45063728
Geraniol attenuates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced oxidative stress and inflammation in mouse skin: possible role of p38 MAP Kinase and NF-κB.Q46588819
Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductaseQ46839455
Original Article: Investigation of Bcl-2 and PCNA in Hepatocellular Carcinoma: Relation to Chronic HCV.Q46961899
Chemoprevention of Diethylnitrosamine-Initiated and Phenobarbital-Promoted Hepatocarcinogenesis in Rats by Sulfated Polysaccharides and Aqueous Extract of Ulva lactuca.Q53217138
Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis.Q54499899
Geraniol, an inhibitor of mevalonate biosynthesis, suppresses the growth of hepatomas and melanomas transplanted to rats and miceQ71512013
Chemopreventive effects of β-ionone and geraniol during rat hepatocarcinogenesis promotion: distinct actions on cell proliferation, apoptosis, HMGCoA reductase, and RhoAQ84143002
P433issue1
P304page(s)37-43
P577publication date2016-03-01
P1433published inYonago Acta MedicaQ15765174
P1476titlePreventive Effect of Geraniol on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats
P478volume59