Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding

scientific article published on October 1991

Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.35.10.2085
P8608Fatcat IDrelease_3spoyghbhbacfaftx4qvg7ikmq
P932PMC publication ID245330
P698PubMed publication ID1759831
P5875ResearchGate publication ID21395621

P2093author name stringCarbon C
Potel G
Fantin B
Vallois JM
Chau NP
Pangon B
Faurisson F
P2860cites workMethod of reliable determination of minimal lethal antibiotic concentrationsQ30451398
Experimental endocarditis. II. Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heartQ34228754
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Comparative efficacy of cefotiam, cefmenoxime, and ceftriaxone in experimental endocarditis and correlation with pharmacokinetics and in vitro efficacyQ35538447
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Examination of gram-negative bacilli from meningitis patients who failed or relapsed on moxalactam therapyQ35641081
Ciprofloxacin penetration into extravascular spaces in a rabbit modelQ35641275
Role of serum protein binding and multiple antibiotic doses in the extravascular distribution of ceftizoxime and cefotaximeQ35761282
Impact of dosage schedule on the efficacy of gentamicin, tobramycin, or amikacin in an experimental model of Serratia marcescens endocarditis: in vitro-in vivo correlationQ36752610
Evaluation of antibiotic diffusion into cardiac vegetations by quantitative autoradiographyQ41265449
A study of amikacin given once versus twice daily in serious infectionsQ41274203
Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection modelsQ42169493
Gentamicin, netilmicin, dibekacin, and amikacin nephrotoxicity and its relationship to tubular reabsorption in rabbitsQ42929705
Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal modelQ43617611
Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentrationQ44483617
Pefloxacin in rabbits: protein binding, extravascular diffusion, urinary excretion and bactericidal effect in experimental endocarditisQ45166730
The Influence of Dosage Regimen on Experimental Gentamicin Nephrotoxicity: Dissociation of Peak Serum Levels from Renal FailureQ45199122
Single, large, daily dosing versus intermittent dosing of tobramycin for treating experimental pseudomonas pneumoniaQ46611376
Once-daily vs. continuous aminoglycoside dosing: efficacy and toxicity in animal and clinical studies of gentamicin, netilmicin, and tobramycinQ46984010
Treatment failures of cefotaxime and latamoxef in meningitis caused by Enterobacter and Serratia spp.Q54395890
Antibiotic therapy of infections due to Pseudomonas aeruginosa in normal and granulocytopenic mice: comparison of murine and human pharmacokineticsQ68857516
Kinetics and bactericidal effect of gentamicin and latamoxef (moxalactam) in experimental Escherichia coli endocarditisQ68872822
Experimental infection with Streptococcus pneumoniae in mice: correlation of in vitro activity and pharmacokinetic parameters with in vivo effect for 14 cephalosporinsQ69572281
The importance of pharmacodynamics in determining the dosing interval in therapy for experimental pseudomonas endocarditis in the ratQ69989265
Penetration of 14C-Ro 13-9904 into tissue cage fluid in rabbitsQ70824524
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectantibioticQ12187
P304page(s)2085-2090
P577publication date1991-10-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleSingle daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding
P478volume35