scholarly article | Q13442814 |
P2093 | author name string | Hozumi Motohashi | |
James Douglas Engel | |||
Lihong Shi | |||
Masayuki Yamamoto | |||
Osamu Tanabe | |||
Mikiko Suzuki | |||
Harumi Y Mukai | |||
Hiromi Yamazaki | |||
P2860 | cites work | The product of the mammalian orthologue of the Saccharomyces cerevisiae HBS1 gene is phylogenetically related to eukaryotic release factor 3 (eRF3) but does not carry eRF3-like activity | Q22008594 |
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin | Q24293797 | ||
An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer | Q24537021 | ||
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13 | Q24633081 | ||
Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation | Q24646904 | ||
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium | Q24655591 | ||
Sickle-cell disease | Q28287003 | ||
Developmental and species-divergent globin switching are driven by BCL11A | Q28506497 | ||
Bcl11a is essential for normal lymphoid development | Q28511014 | ||
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen | Q29615061 | ||
c-Myb is critical for B cell development and maintenance of follicular B cells | Q30438061 | ||
c-Myb is essential for early T cell development | Q30448775 | ||
A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene | Q33961661 | ||
Genome-wide association study of hematological and biochemical traits in a Japanese population | Q34097468 | ||
Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts | Q34102833 | ||
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. | Q34674466 | ||
A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression | Q35001653 | ||
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium | Q35025798 | ||
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development | Q35759986 | ||
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults | Q36090188 | ||
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis | Q36136740 | ||
Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation | Q37099963 | ||
MYB function in normal and cancer cells | Q37198576 | ||
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis | Q38335144 | ||
Transgene insertion in proximity to the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation | Q39124965 | ||
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. | Q39908659 | ||
Thalassemia: recent insights into molecular mechanisms | Q40128610 | ||
Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4. | Q40146211 | ||
An erythroid specific enhancer upstream to the gene encodin the cell-type specific transcription factor GATA-1 | Q40507505 | ||
c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression. | Q42946150 | ||
KLF1 regulates BCL11A expression and γ- to β-globin gene switching | Q42950072 | ||
A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo | Q44251132 | ||
The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells | Q45853151 | ||
Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene. | Q47962866 | ||
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans. | Q53533032 | ||
cMYB is involved in the regulation of fetal hemoglobin production in adults. | Q54591078 | ||
Mortality in sickle cell disease. Life expectancy and risk factors for early death. | Q55065788 | ||
Beta-thalassaemia intermedia: is it possible consistently to predict phenotype from genotype? | Q74122253 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Hereditary persistence of fetal hemoglobin | Q4351777 |
P304 | page(s) | 1687-1695 | |
P577 | publication date | 2013-02-19 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model | |
P478 | volume | 33 |
Q47261747 | A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression |
Q33850615 | An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference |
Q37071189 | Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease |
Q38167823 | Diagnosis and prevention of thalassemia |
Q37517470 | Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia |
Q26822810 | Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathies |
Q38995849 | Fetal hemoglobin regulation in β-thalassemia: heterogeneity, modifiers and therapeutic approaches |
Q50061134 | Genetic Basis and Genetic Modifiers of β-Thalassemia and Sickle Cell Disease |
Q51080070 | Genetic Variants at BCL11A and HBS1L-MYB loci Influence Hb F Levels in Chinese Zhuang β-Thalassemia Intermedia Patients. |
Q35087288 | Genotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach |
Q38592271 | HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers |
Q36777717 | Hydroxyurea down-regulates BCL11A, KLF-1 and MYB through miRNA-mediated actions to induce γ-globin expression: implications for new therapeutic approaches of sickle cell disease |
Q89184052 | Impact of Genetic Determinants of HbA1c on Type 2 Diabetes Risk and Diagnosis |
Q39399184 | Molecular basis of β thalassemia and potential therapeutic targets |
Q41232448 | Multiple Testing in the Context of Gene Discovery in Sickle Cell Disease Using Genome-Wide Association Studies. |
Q47447659 | Ribosomopathies: There's strength in numbers. |
Q35656305 | Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1. |
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