Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

scientific article published on January 1994

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1460-2075.1994.TB06267.X
P932PMC publication ID394814
P698PubMed publication ID8313879

P50authorJean-Philippe PinQ33113596
P2093author name stringS F Heinemann
J Bockaert
C Joly
P2860cites workFunctional analysis of the cytoplasmic domains of the human thyrotropin receptor by site-directed mutagenesis.Q38337870
Chimeric muscarinic cholinergic: beta-adrenergic receptors that activate Gs in response to muscarinic agonistsQ38341216
Structural basis of beta-adrenergic receptor function.Q41235089
Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4.Q41562071
Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysisQ41643392
Two adjacent cysteine residues in the C-terminal cytoplasmic fragment of bovine rhodopsin are palmitylatedQ44241904
Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengersQ44850402
G protein-bound conformation of mastoparan-X, a receptor-mimetic peptideQ46477155
Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brainQ48224778
Neurotensin and acetylcholine evoke common responses in frog oocytes injected with rat brain messenger ribonucleic acidQ48262329
The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells.Q48329514
Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine.Q48370279
In Vitro and In Vivo Pharmacology oftrans-andcis-(±)-1-Amino-1,3-Cyclopentanedicarboxylic Acid: Dissociation of Metabotropic and Ionotropic Excitatory Amino Acid Receptor EffectsQ48733375
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmittersQ48876688
Quisqualate receptor-mediated depression of calcium currents in hippocampal neuronsQ49014674
G0 is a major growth cone protein subject to regulation by GAP-43.Q49017518
Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptorsQ50800154
L-AP4 inhibits calcium currents and synaptic transmission via a G- protein-coupled glutamate receptorQ67490169
Detection of G protein-activator regions in M4 subtype muscarinic, cholinergic, and alpha 2-adrenergic receptors based upon characteristics in primary structureQ67845721
Specific activation of Gs by synthetic peptides corresponding to an intracellular loop of the beta-adrenergic receptorQ67914000
Coupling of a mutated form of the human beta 2-adrenergic receptor to Gi and Gs. Requirement for multiple cytoplasmic domains in the coupling processQ67914017
Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylationQ68260026
A simple structure encodes G protein-activating function of the IGF-II/mannose 6-phosphate receptorQ68473070
Activation of a Large-conductance Ca2+-Dependent K+ Channel by Stimulation of Glutamate Phosphoinositide-coupled Receptors in Cultured Cerebellar Granule CellsQ74430073
Rhodopsin mutants that bind but fail to activate transducinQ24300261
A simple method for displaying the hydropathic character of a proteinQ26778481
Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptorQ28251690
Sequence and expression of a metabotropic glutamate receptorQ28280066
Glutamate stimulates inositol phosphate formation in striatal neuronesQ28282165
A new type of glutamate receptor linked to inositol phospholipid metabolismQ28282769
Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cellsQ28326925
L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclaseQ28327851
Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transductionQ28564903
Molecular diversity of glutamate receptors and implications for brain functionQ28611078
Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytesQ31001629
A family of metabotropic glutamate receptorsQ31159811
Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypesQ33923611
Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341.Q34042138
Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).Q34167134
Three cytoplasmic loops of rhodopsin interact with transducinQ34302756
Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological functionQ34629220
Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificityQ34681325
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsQ35227301
Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates FunctionQ35229110
The hydrophobic moment detects periodicity in protein hydrophobicityQ36245139
Pharmacological and functional characteristics of metabotropic excitatory amino acid receptorsQ37566538
Analysis of stimulation-G protein subunit coupling by using active insulin-like growth factor II receptor peptideQ37592553
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous systemQ38272501
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)342-348
P577publication date1994-01-01
P1433published inThe EMBO JournalQ1278554
P1476titleDomains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors
P478volume13